Abstract：
Traditional medicine systems around the globe, like Unani, Ayurveda and traditional Chinese medicine, include a number of sugar-based formulations, which contain a large amount of saccharide-containing sweetener, such as honey, sucrose or jaggery. With pervasive lifestyle disorders throughout the world, there have been discussions to consider alternative sweetening agents. Here, from the perspective of Unani medicine, we discuss how the saccharide-based sweeteners may be an essential component of these traditional preparations, like electuaries, which may be deprived of their bioactivities without these saccharides. With contemporary researches, it is known that apart from their own therapeutic effects, saccharides also form deep eutectic solvents which help in enhancing the bioactivity of other ingredients present in crude drugs. In addition, they provide energy for fermentation which is essential for biotransformation of compounds. Interestingly, the sugars also increase the shelf-life of these compound drugs and act as natural preservatives. On the basis of this review, we strongly believe that saccharide-based sweeteners are an essential component of traditional medicines and not merely an excipient.
摘要：
世界各地的传统医学系统，像Unani,阿育吠陀和中药，包括一些糖基配方，其中含有大量含糖甜味剂，比如蜂蜜,蔗糖或参差不齐。世界各地普遍存在的生活方式障碍，一直在讨论考虑替代甜味剂。这里,从Unani医学的角度来看，我们讨论了糖类甜味剂如何成为这些传统制剂的重要组成部分，像选民一样，如果没有这些糖，它们可能会被剥夺生物活性。随着当代研究，众所周知，除了它们自己的治疗效果，糖类也形成低共熔溶剂,其有助于增强原料药中存在的其他成分的生物活性。此外,它们为发酵提供能量，这对于化合物的生物转化至关重要。有趣的是,糖还增加了这些复合药物的保质期，并充当天然防腐剂。在此回顾的基础上,我们坚信糖基甜味剂是传统药物的重要组成部分，而不仅仅是赋形剂。
