Trastorno del espectro autista

  • 文章类型: Journal Article
    背景:心理理论(ToM)是人类感知的能力,解释,并归因于其他人的精神状态,这种认知功能的改变是自闭症谱系障碍(ASD)的核心症状。在其他神经发育障碍中,如儿童期发作的强迫症(OCD)和Tourette综合征(TS),可以表现为认知功能障碍,ToM的研究较少,尤其是在年轻人中。该研究的目的是比较被诊断患有强迫症的年轻人群体之间的高级ToM,TS,或ASD和对照组。
    方法:对年龄在11至17岁之间,主要诊断为强迫症的男性患者进行临床访谈(n=19),TS(n=14),或ASD(n=18),和对照组(n=20)。我们使用评估智商和精神症状严重程度的工具,以及评估ToM的任务(“日常生活中的故事”任务和“阅读眼睛中的心灵”测试)。
    结果:患有TS和ASD的年轻人在解决高级ToM任务方面存在相似的困难,而儿童期发病的强迫症患者的结果与对照组相似。
    结论:在ASD以外的其他神经发育障碍中,ToM发生改变,比如TS。
    BACKGROUND: Theory of mind (ToM) is the human ability to perceive, interpret, and attribute the mental states of other people, and the alteration of this cognitive function is a core symptom of autistic spectrum disorder (ASD). In such other neurodevelopmental disorders as childhood-onset obsessive-compulsive disorder (OCD) and Tourette syndrome (TS) that can present with cognitive dysfunctions, ToM has been less extensively studied, especially in the young population. The aim of the study was to compare advanced ToM between groups of young people diagnosed with OCD, TS, or ASD and a control group.
    METHODS: Clinical interviews were conducted with male patients aged between 11 and 17 years with a main diagnosis of OCD (n = 19), TS (n = 14), or ASD (n = 18), and a control group (n = 20). We administered instruments for estimating intelligence quotient and severity of psychiatric symptoms, and tasks to evaluate ToM (the \"Stories from everyday life\" task and the \"Reading the mind in the eyes\" test).
    RESULTS: Young people with TS and with ASD present similar difficulties in solving advanced ToM tasks, whereas patients with childhood-onset OCD present similar results to controls.
    CONCLUSIONS: ToM is altered in other neurodevelopmental disorders beyond ASD, such as TS.
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  • 文章类型: Systematic Review
    背景:沟通和语言技能是自闭症谱系障碍(ASD)患者受影响最严重的领域之一。当被诊断患有ASD的孩子生活在双语环境中时,父母经常担心他们的孩子是否应该同时学习两种语言,向专家寻求建议。尽管缺乏任何负面影响的证据,一些专业人士在这个问题上意见不一。在这篇系统综述中,我们研究了双语是否会影响ASD儿童的语言发展。
    方法:我们回顾了在4个不同数据库中发表的文献。应用一系列选择标准后,我们选择了12篇科学文章,包括328名被诊断患有ASD的儿童(169名双语和159名单语),年龄从3到12岁不等。使用涵盖多个领域的不同接受和表达性语言评估工具对这些患者进行了评估。评估是直接对孩子们进行的,尽管在一些研究中也对父母进行了间接评估.
    结论:关于双语不会给3岁以下ASD儿童的语言发展带来任何额外困难的说法,似乎已经达成共识。
    BACKGROUND: Communication and language skills are among the most severely affected domains in individuals with autistic spectrum disorder (ASD). When a child diagnosed with ASD lives in a bilingual environment, the parents often express concerns about whether their child should learn both languages simultaneously, turning to specialists for advice. Despite the lack of evidence of any negative effect, some professionals disagree on this subject. In this systematic review we study whether bilingualism affects language development in children with ASD.
    METHODS: We reviewed the literature published in 4 different databases. After applying a series of selection criteria, we selected 12 scientific articles, including a total of 328 children diagnosed with ASD (169 bilingual and 159 monolingual), with ages ranging from 3 to 12 years. These patients were evaluated with different receptive and expressive language assessment instruments covering several areas. The assessments were performed directly on the children, although indirect assessment of parents was also performed in some studies.
    CONCLUSIONS: There seems to be consensus regarding the assertion that bilingualism does not entail any additional difficulty for language development in children with ASD from the age of 3.
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  • 文章类型: Systematic Review
    自闭症谱系障碍(ASD)具有不同的特征,对社会产生影响,交流和感觉运动(SM)水平。SM特征是姿势控制(PC)问题。有各种运动干预策略(MIS),但相对于LC的好处是没有被广泛分析的。目的是在ASD儿童和青少年的PC上描述MIS及其结果。搜索PubMed,Scopus,进行了WebofScience和Cochrane。共有8篇文章符合资格标准。所有MIS对PC的改进均显示出有益的结果。管理信息系统性质各异(舞蹈练习,个性化的身体活动,视频游戏,太极拳,跆拳道和虚拟现实)。有必要改进设计并考虑偏差的风险,因为它们限制了结果的范围。
    Autism spectrum disorder (ASD) has varied characteristics with an impact at the social, communicative and sensorimotor (SM) level. An SM feature is postural control (PC) problems. There are various motor intervention strategies (MIS), but the benefit over LC is something that has been analyzed less extensively. The objective was to describe the MIS and its results on the PC of children and adolescents with ASD. A search of PubMed, Scopus, Web of Science and Cochrane was performed. A total of eight articles met the eligibility criteria. All MIS showed beneficial results on the improvement of PC. The MIS were of a varied nature (dance practice, personalized physical activity, video games, Tai Chi Chuan, Taekwondo and virtual reality). It is necessary to improve the designs and consider the risks of bias, since they limit the scope of the results.
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  • 文章类型: Journal Article
    背景:心理理论(ToM)是人类感知的能力,解释,并归因于其他人的精神状态,这种认知功能的改变是自闭症谱系障碍(ASD)的核心症状。在其他神经发育障碍中,如儿童期发作的强迫症(OCD)和Tourette综合征(TS),可以表现为认知功能障碍,ToM的研究较少,尤其是在年轻人中。该研究的目的是比较被诊断患有强迫症的年轻人群体之间的高级ToM,TS,或ASD和对照组。
    方法:对年龄在11至17岁之间,主要诊断为强迫症的男性患者进行临床访谈(n=19),TS(n=14),或ASD(n=18),和对照组(n=20)。我们使用评估智商和精神症状严重程度的工具,以及评估ToM的任务(“日常生活中的故事”任务和“阅读眼睛中的心灵”测试)。
    结果:患有TS和ASD的年轻人在解决高级ToM任务方面存在相似的困难,而儿童期发病的强迫症患者的结果与对照组相似。
    结论:在ASD以外的其他神经发育障碍中,ToM发生改变,比如TS。
    BACKGROUND: Theory of mind (ToM) is the human ability to perceive, interpret, and attribute the mental states of other people, and the alteration of this cognitive function is a core symptom of autistic spectrum disorder (ASD). In such other neurodevelopmental disorders as childhood-onset obsessive-compulsive disorder (OCD) and Tourette syndrome (TS) that can present with cognitive dysfunctions, ToM has been less extensively studied, especially in the young population. The aim of the study was to compare advanced ToM between groups of young people diagnosed with OCD, TS, or ASD and a control group.
    METHODS: Clinical interviews were conducted with male patients aged between 11 and 17 years with a main diagnosis of OCD (n=19), TS (n=14), or ASD (n=18), and a control group (n=20). We administered instruments for estimating intelligence quotient and severity of psychiatric symptoms, and tasks to evaluate ToM (the \"Stories from everyday life\" task and the \"Reading the mind in the eyes\" test).
    RESULTS: Young people with TS and with ASD present similar difficulties in solving advanced ToM tasks, whereas patients with childhood-onset OCD present similar results to controls.
    CONCLUSIONS: ToM is altered in other neurodevelopmental disorders beyond ASD, such as TS.
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  • 文章类型: Journal Article
    背景:沟通和语言技能是自闭症谱系障碍(ASD)患者受影响最严重的领域之一。当被诊断患有ASD的孩子生活在双语环境中时,父母经常担心他们的孩子是否应该同时学习两种语言,向专家寻求建议。尽管缺乏任何负面影响的证据,一些专业人士在这个问题上意见不一。在这篇系统综述中,我们研究了双语是否会影响ASD儿童的语言发展。
    方法:我们回顾了在4个不同数据库中发表的文献。应用一系列选择标准后,我们选择了12篇科学文章,包括328名被诊断患有ASD的儿童(169名双语和159名单语),年龄从3到12岁不等。使用涵盖多个领域的不同接受和表达性语言评估工具对这些患者进行了评估。评估是直接对孩子们进行的,尽管在一些研究中也对父母进行了间接评估.
    结论:关于双语不会给3岁以下ASD儿童的语言发展带来任何额外困难的说法,似乎已经达成共识。
    BACKGROUND: Communication and language skills are among the most severely affected domains in individuals with autistic spectrum disorder (ASD). When a child diagnosed with ASD lives in a bilingual environment, the parents often express concerns about whether their child should learn both languages simultaneously, turning to specialists for advice. Despite the lack of evidence of any negative effect, some professionals disagree on this subject. In this systematic review we study whether bilingualism affects language development in children with ASD.
    METHODS: We reviewed the literature published in 4 different databases. After applying a series of selection criteria, we selected 12 scientific articles, including a total of 328 children diagnosed with ASD (169 bilingual and 159 monolingual), with ages ranging from 3 to 12 years. These patients were evaluated with different receptive and expressive language assessment instruments covering several areas. The assessments were performed directly on the children, although indirect assessment of parents was also performed in some studies.
    CONCLUSIONS: There seems to be consensus regarding the assertion that bilingualism does not entail any additional difficulty for language development in children with ASD from the age of 3.
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  • 文章类型: Journal Article
    背景:新冠肺炎大流行产生了前所未有的多模式(健康,职业,经济,和社会危机,这将影响发展中国家。作为一种预防措施的约束本身就是一种威胁,会产生社会影响。大流行和禁闭已成为影响家庭及其子女的社会心理逆境因素。大流行期间,患有精神疾病的儿童和青少年可能会出现症状恶化。然而,对此知之甚少,因为在大流行期间对这一人群的研究很少。
    目的:回顾当前文献中有关大流行对先前患有精神疾病的儿童和青少年的影响的数据。
    方法:使用PubMed进行了文献检索,Scielo和,由于大流行情况的特殊情况,直接使用互联网搜索引擎。包括英语和西班牙语论文。
    结果:发现的信息在以下部分中介绍:大流行期间的家庭和儿童,大流行期间儿童和青少年精神障碍的评估,大流行期间预先存在的精神疾病,和心灵感应护理。提供了关于注意力缺陷多动障碍的具体信息,自闭症谱系障碍,智力残疾,焦虑症,强迫症,和创伤后应激障碍。目前由COVID-19和监禁引起的大流行是一种社会心理逆境,威胁着家庭的稳定。这种压力源可以导致先前精神障碍的症状恶化。患有精神疾病的儿童和青少年是弱势群体,需要专门护理。Telepsychiatry正在成为一种具有多种优势的方式。
    BACKGROUND: The Covid-19 pandemic has generated an unprecedented multimodal (health, occupational, economic, and social crisis, which will impact developing countries. Confinement as a preventive measure is itself a threat that produces a social impact. Pandemic and confinement have become a psychosocial adversity factor that affects families and their children. During the pandemic, children and adolescents with a psychiatric disorder may experience exacerbation of their symptoms. However, little is known about this, since studies on this population during the pandemic are scarce.
    OBJECTIVE: To review the data available in the current literature on the effect of the pandemic on children and adolescents with a previous psychiatric disorder.
    METHODS: A literature search was carried out using PubMed, Scielo and, due to the exceptional conditions of the pandemic situation, directly using internet search engines. Both English and Spanish papers were included.
    RESULTS: The information found is presented in the following sections: family and children during the pandemic, evaluation of mental disorders in children and young people during the pandemic, pre-existing psychiatric disorders during the pandemic, and telepsychiatric care. Specific information is presented on attention deficit hyperactivity disorder, autism spectrum disorder, intellectual disability, anxiety disorder, obsessive compulsive disorder, and post-traumatic stress disorder. The current pandemic due to COVID-19 and confinement are a psychosocial adversity that threatens the stability of the family. Such a stressor can cause exacerbation of symptoms of a previous mental disorder. Children and adolescents with psychiatric disorders are a vulnerable population and require specialised care. Telepsychiatry is becoming a modality with multiple advantages.
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  • 文章类型: Journal Article
    In recent years, there has been an increase in studies of the implications of the gut microbiota (GM) in children with autism spectrum disorder (ASD). There is a hypothesis which propose a relationship between the emotional state and the abundance of intestinal microbes through the so-called microbiota-intestine-brain axis. In this sense, dysbiotic GM could be a contributing factor to the appearance of ASD. This systematic review article analyzes the results of the intervention using prebiotics (carrot powder, vitamin A, partially hydrolyzed guar gum, galactooligosaccharides, etc.), probiotics (mainly: Lactobacillus, Bifidobacterium, etc.) and transplantation of fecal microbiota in ASD children. In conclusion, the results of the initial studies suggest changes in ASD symptoms, gastro-intestinal symptoms and GM composition after the interventions. However, the results should be taken with caution because there are very few studies that analyze the efficacy of long-term treatments and the different combinations of them.
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  • 文章类型: Journal Article
    背景:自闭症谱系障碍(ASD)的特征是社交交流中的普遍缺陷,刻板印象,和有限的利益。ASD患有其他精神疾病,使其日常功能恶化,降低了他们及其家人的生活质量。
    方法:为了确定可能影响其他精神疾病的家庭环境特征,这项研究的重点是父母压力和心理困扰作为可能的危险因素。在ASD学龄前儿童(2-6岁)中,对父母的压力与心理困扰之间的关系及其与共存的心理病理学之间的关系进行了横断面研究。
    结论:父母的高水平压力和心理困扰已经相关,从童年开始,伴随着精神症状,特别是情绪和行为问题(p<0.05)。然而,需要进一步的纵向研究才能更好地理解这些变量之间的因果关系及其可能的双向关系.
    BACKGROUND: The Autistic Spectrum Disorders (ASD) are characterised by general deficits in social communication, stereotypes, and restricted interests. The ASD have a high prevalence of additional psychiatric disorders that make their daily functioning worse, and reduces the quality of life of them and their families.
    METHODS: In an effort to identify family environmental characteristics that may influence in the course of additional psychiatric disorders, this study has focused on the symptoms of parental stress and psychological distress as possible risk factors. A cross-section study was carried out on the relationship between the stress and psychological distress of the parents and its relationship with co-existing psychopathology in a population of pre-school children with ASD (2-6 years).
    CONCLUSIONS: High levels of stress and psychological distress of the parents arealready associated, since early childhood, with co-existing psychiatric symptoms, specifically with emotional and behavioural problems (p < 0.05). However, further longitudinal studies are needed for a better understanding of the causal relationship between these variables and their possible bidirectional relationship.
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  • 文章类型: Journal Article
    Disruptive behaviors can be of comparable or greater concern to parents than the core symptoms of Autism Spectrum Disorder (ASD). Provision of effective interventions to address these behaviors within the first year of initial diagnosis holds great potential for improving the child\'s, parents\', and family\'s functioning. We piloted a four-session, manualized, positive parenting program on 21 parents of newly diagnosed children ages 2 through 12 years using a mixed methods design. Seventy-five percent of parents completed four sessions, with 100% reporting high levels of service satisfaction. Preliminary results indicated clinically and statistically significant reductions in child maladaptive behaviors, as well as improvements in parental and family functioning. Practitioners and parents identified several potential implementation adaptations, including additional sessions to focus on ASD education and real-time parent-child interactions. Taken as a whole, these data suggest that a brief positive parenting intervention may be a feasible way to improve child, parent, and family functioning during the first year of ASD diagnosis. Findings point to the need for additional research to determine treatment efficacy and to assist with the identification of moderators and mediators of effects.
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  • 文章类型: Journal Article
    Autism Spectrum Disorders (ASD) are characterized by impairments in communication and social interaction, as well as restricted and repetitive patterns of behavior. They have a prevalence of 0.6% in the general population, although there are no national statistics. Even though their evolution is variable, it has been observed that early intervention is an important factor determining prognosis. The aim of this study is to update concepts regarding the current available evidence on the importance of early intervention. After analyzing the collected information, the importance of early intervention programs for children with ASD is confirmed, as well as the role of pediatricians and other health professionals in the early detection of these disorders.
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