Successful aging

成功老化
  • 文章类型: Journal Article
    目标:尽管先前的研究已经确定了成功衰老(SA)中的种族/族裔和性别差异,组内的异质性很少被研究。因此,我们探索了老年黑人女性的各种衰老经历。
    方法:我们使用了2010/2012年美国健康与退休研究,对完成心理社会留守问卷的黑人女性进行限制性分析(N=1,186)。我们使用身体健康指标进行了潜在类别分析(LCA),心理健康,社会支持/紧张,和社会参与。
    结果:根据其独特特征,确定并标记了六个SA潜在类别:虚弱,孤立的,征税,独立,活泼的,和强大的。体弱多病的阶级身体都不好,孤立的阶级虽然身体健康状况不佳,但也缺乏社会关系。虽然两人都有平均的身体健康和心理健康,与高支持(和无合作)的独立阶级相比,纳税阶级经历了高水平的社会支持和社会压力。活泼健壮的班级表现出很高的身体健康和心理健康,高社会支持/低社会压力,和高度的社会参与,但活泼的女性(23%的受访者)没有伴侣,健壮的女性(16%的受访者)有伴侣.健壮的班级拥有最高的身体和心理健康,以及所有阶层的最佳社会关系。
    结论:使用具有全国代表性的数据,我们揭示了黑人女性衰老经历的显著异质性。尽管许多人面临艰难的衰老经历,39%的老年黑人女性很适合SA框架。未来的工作应该认识到,黑人女性的衰老经历不是同质的。
    OBJECTIVE: Although prior research has identified racial/ethnic and gender differences in successful aging (SA), heterogeneity within groups has been little examined. We consequently explore the variety of aging experiences among older Black women.
    METHODS: We used the 2010/2012 U.S. Health and Retirement Study, limiting analyses to Black women who completed the Psychosocial Leave-Behind Questionnaire (N = 1,186). We conducted latent class analysis (LCA) using indicators of physical health, psychological well-being, social support/strain, and social engagement.
    RESULTS: Six SA latent classes were identified and labeled according to their distinctive characteristics: infirm, isolated, taxed, independent, vivacious, and robust. The infirm class had uniformly poor health, while the isolated class was in poor physical health but also lacked social relations. Although both had average physical health and psychological well-being, the taxed class experienced high levels of social support and social strain compared to the high support (and unpartnered) independent class. The vivacious and robust classes exhibited high physical health and psychological well-being, high social support/low social strain, and high social engagement, but vivacious women (23% of respondents) were unpartnered and robust women (16% of respondents) were partnered. The robust class had the highest physical and psychological well-being, and best social relations across all classes.
    CONCLUSIONS: Using nationally representative data, we reveal significant heterogeneity in Black women\'s aging experiences. Although many face difficult aging experiences, 39% of older Black women fit the SA framework well. Future work should recognize that Black women\'s aging experiences are not homogenous.
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  • 文章类型: Journal Article
    目标:退伍军人的衰老经历为成功的衰老提供了重要的见解,并为受不同健康和社会需求限制的后期生活环境提供了手段。当退伍军人承受如此多的压力并对以后的生活产生严重的健康和社会后果时,他们可以成功地衰老吗?退伍军人可以为开发完善成功衰老的综合方法提供宝贵的经验教训,确保不同老年人群的包容性。基于Rowe和Kahn关于成功衰老的想法,我们利用“主动衰老”的互补概念来探索是否有独特的因素,特点,以及支持退伍军人积极衰老的干预措施,与非退伍军人相比。
    方法:在医学的9个数据库中进行了快速回顾和证据综合,心理学,人类学,社会学,和公共卫生,以搜索同行评审的文章和研究报告。
    结果:研究结果表明,将健康和社会层面联系起来的计划可以支持退伍军人的积极老龄化,即促进积极的身体和认知生活方式以及社会联系和参与的干预措施。此类计划和干预措施有助于预防和打击身心健康下降,并提高生活质量和福祉。
    结论:研究结果对更广泛的退伍军人和非退伍军人人群都有影响,因为即使人们有独特的健康和社会需求,他们也可以积极地衰老。
    OBJECTIVE: The aging experiences of military veterans provide critical insights into what successful aging is and means for later life contexts constrained by distinct health and social needs. Can veterans \'successfully\' age when they are exposed to so many stressors with serious health and social consequences for later life? Veterans can offer valuable lessons for developing comprehensive approaches to refining successful aging, ensuring inclusivity of different older populations. Building on Rowe and Kahn\'s idea of successful aging, we utilize the complementary concept of \'active aging\' to explore if there are unique factors, characteristics, and interventions that support active aging in veterans, compared to non-veteran populations.
    METHODS: A rapid review and evidence synthesis was conducted across 9 databases in medicine, psychology, anthropology, sociology, and public health to search for peer-reviewed articles and research reports.
    RESULTS: Findings suggest that programs linking health and social dimensions can support the active aging of veterans, namely interventions promoting active physical and cognitive lifestyle as well as social connectedness and engagement. Such programs and interventions help prevent and combat mental and physical health decline and increase quality of life and well-being.
    CONCLUSIONS: Findings have implications for veteran and non-veteran populations more broadly, as people can actively age even when they have unique health and social needs.
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    文章类型: Journal Article
    Computerized cognitive training (CCT) is a rapidly developing area of cognitive rehabilitation at the intersection of information technology and healthcare, the constantly updated results of which can be successfully translated into practical application in clinical medicine and in particular in gerontology. The basis of CCT, as a non-invasive method of influencing the functional activity of the brain and the processes of neuroplasticity, is software for stimulating cognitive functions in order to improve their productivity. The level of scientific and practical interest in CCP technology is growing rapidly. The article reports on the current state of research on the use of CCT aimed at correcting cognitive impairment. The purpose of this work is to systematize the available scientific data in this area, as well as to promote further integration of research in the field of information technology into clinical practice, in particular, to study the potential of CCT as a promising therapeutic tool in the paradigm of successful aging and prevention of the progression of cognitive impairment. This noninvasive intervention may improve global cognitive function in patients with clinically defined impairments and during normal aging in cognitively healthy older adults. However, new studies with fully comparable protocols are needed to evaluate in more detail the duration of the effect and the effectiveness of CCT in preventing cognitive decline in the long term.
    Компьютеризированный когнитивный тренинг (ККТ) представляет собой быстро развивающееся направление когнитивной реабилитации на пересечении информационных технологий и здравоохранения, постоянно обновляемые результаты которого возможно с успехом транслировать в сферу практического применения в клинической медицине и, в частности, в геронтологии. Основу ККT, как неинвазивного метода воздействия на функциональную активность мозга и процессы нейропластичности, составляет программное обеспечение для стимуляции когнитивных функций с целью улучшения их продуктивности. Научный и практический интерес к технологии ККТ растет быстрыми темпами, и в определенной степени он даже больше, чем к некоторым другим областям реабилитации, ориентированным на здоровое старение. В статье сообщается о современном состоянии исследований применения ККТ, направленного на коррекцию когнитивных нарушений. Цель настоящей работы — не только систематизировать имеющиеся научные данные в этой области, но также способствовать дальнейшей интеграции быстро развивающихся исследований в области информационных технологий в клиническую практику. В частности, необходимо изучить потенциал ККТ как перспективного терапевтического инструмента в парадигме успешного старения и профилактики прогрессирования когнитивных нарушений. Проведенный анализ показывает, что такое вмешательство может улучшить глобальные когнитивные функции у пациентов с клинически установленными нарушениями и в процессе нормального старения у когнитивно-здоровых людей пожилого возраста. Однако необходимы новые исследования с максимально сопоставимыми протоколами, чтобы более детально оценить длительность эффекта и результативность ККТ для предотвращения снижения когнитивных функций в долгосрочной перспективе.
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  • 文章类型: Journal Article
    这项研究旨在确定成功衰老(SA)的患病率,并检查2016年至2020年之间SA指标变化与SA状态变化的关联。该研究包括548名韩国虚弱和衰老队列研究(KFACS)参与者。与2016年获得SA的参与者相比(N=393,71.7%),2020年,患有SA的老年人数量减少了7.8%.在保留SA的老年人中(SA→SA组,54%),成功维持指标的老年人数量相对较少,包括慢性病(不→不,9.5%),就业(是→是,12.2%),和志愿者活动(是→是,2.9%)。我们的研究结果表明,需要采取干预措施来加强老年人的身体和心理功能,需要保证社会支持,以提高老年人的社会参与度。
    This study aims to determine the prevalence of successful aging (SA) and examine the association of changes in the indicators of SA and variations in SA status between 2016 and 2020. The study included 548 participants recruited for the Korean Frailty and Aging Cohort Study (KFACS). Compared to participants who achieved SA in 2016 (N = 393, 71.7%), the number of older adults with SA decreased by 7.8% in 2020. Among older adults preserving SA (SA→SA group, 54%), there were relatively small numbers of older adults who successfully maintained indicators, including chronic diseases (no→no, 9.5%), employment (yes→yes, 12.2%), and volunteer activities (yes→yes, 2.9%). Our findings suggest that interventions to strengthen the physical and psychological function of older adults are needed, and social support needs to be guaranteed to improve social engagement for older adults.
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  • 文章类型: Journal Article
    目的:成功衰老是老年学文献的支柱,但这并不是没有批评,包括研究和测量的通常有限的方式,以及在其表述和理解中排除老年人的声音。这项研究试图通过对多个国家的定性调查来解决这些问题。
    方法:这是一种混合方法,横截面,探索性研究,使用在线调查。接受调查的国家包括澳大利亚,新西兰,联合王国,爱尔兰,加拿大,和美国。65岁及以上的参与者被要求在一个开放式调查项目中描述成功的衰老对他们意味着什么。使用总结性内容分析来检查答复。
    结果:1,994名参与者定义了成功的衰老,发现了六个主题和20个子主题。与成功衰老完全或主要与没有疾病和衰退有关的观念相反,这项研究中最突出的主题是“积极,独立,并参与“作为成功的标志。
    结论:虽然健康和健康维护存在于其他主题中,这些发现支持了成功老龄化的多维定义,该定义促进了老年人的观点.未来的研究应该寻求进一步调查环境因素影响成功衰老定义的方式,包括文化,性别和性别认同,种族和民族,社会经济背景。
    OBJECTIVE: Successful aging is a mainstay of the gerontological literature, but it is not without criticism, including the often-limited way that it is studied and measured as well as the exclusion of older adults\' voices in its formulation and understanding. This study sought to address these issues through a qualitative investigation across multiple countries.
    METHODS: This was a mixed-methods, cross-sectional, exploratory study, using an online survey. Nations that received the survey included Australia, New Zealand, the United Kingdom, Ireland, Canada, and the Unites States. Participants aged 65 and older were asked to describe what successful aging means to them in an open-ended survey item. Summative content analysis was utilized to examine the responses.
    RESULTS: Successful aging was defined by 1,994 participants, and six themes along with 20 subthemes were found. In contrast to conception that successful aging is solely or predominantly related to the absence of disease and decline, the most prominent theme in this study was \"active, independent, and engaged\" as the hallmark of success.
    CONCLUSIONS: While health and health maintenance were present in other themes, these findings support a multidimensional definition of successful aging that promotes the perspectives of older people. Future research should seek to further investigate the ways in which person-in-environment factors influence definitions of successful aging, including culture, gender and gender identity, race and ethnicity, and socioeconomic background.
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  • 文章类型: Journal Article
    目标:人类历史上第一次,老年人的数量将超过儿童,而且越来越多的人将独自生活,缺乏一个或多个核心家庭纽带。这种前所未有的转变需要重新评估现有的“成功老化”模型,特别是在长期护理政策方面。
    方法:本文借鉴了来自多个公开来源的国家级数据(例如,世界银行,经济合作与发展组织,我们的数据世界,和世界价值观调查)来研究跨国发展模式,健康,人口统计学,资源和政策,和文化价值观低,middle-,和高收入国家。
    结果:尽管各国之间存在很大的异质性,国家层面的模式说明了独自生活的经济特权和“成功老龄化”机会在高收入国家的主导地位。关于家庭的文化价值观反映了经济发展的标准模式,然而,友谊成为一种特别一致的全球价值。在国家一级,在收入较高的国家,独居和健康与国内不平等程度较低相关。
    结论:在某些情况下,老化“单独”是一个风险因素,也是他人特权的标志。“成功老龄化”的模式在低收入国家或高度不平等国家在很大程度上是无法获得的,因此,需要彻底结合全球现实,或最终放弃,转而支持更细微的结构观点。假设有家庭存在的长期护理政策将在所有全球背景下随着时间的推移产生越来越大的风险,并且是未来健康老龄化政策的一个关键脆弱性。
    OBJECTIVE: For the first time in human history, older adults will outnumber children and a substantial and growing proportion will live alone and lack one or more nuclear family tie. Such unprecedented shifts require a reevaluation of existing models of \"successful aging\", particularly in terms of long-term care policies.
    METHODS: This paper draws on country-level data from multiple publicly available sources (e.g., World Bank, Organization for Economic Cooperation and Development, Our World in Data, and the World Values Survey) to examine cross-national patterns of development, health, demography, resources and policies, and cultural values in low-, middle-, and high-income countries.
    RESULTS: Although there exists substantial heterogeneity across countries, country-level patterns illustrate the economic privilege of living alone and the dominance of \"successful aging\" opportunities in high income countries. Cultural values about family reflect standard patterns of economic development, yet friendship emerges as a particularly consistent global value. At the country-level, living alone and health are associated in higher income countries with lower within-country inequality.
    CONCLUSIONS: Aging \"alone\" is a risk factor in some contexts, yet a marker of privilege in others. Models of \"successful aging\" are largely unobtainable in lower income countries or high inequality countries, and therefore require a thorough incorporation of global realities, or final abandonment in favor of more nuanced structural perspectives. Long-term care policies that assume the presence of family will yield increasing risk over time across all global contexts and represent a key vulnerability in the future of healthy aging policy.
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  • 文章类型: Journal Article
    由于衰老和COVID-19大流行导致的合并症预计会导致老年人的死亡焦虑。这项研究旨在评估死亡焦虑的患病率及其对患有慢性病的老年人的心理健康和成功衰老的影响。对79名患有慢性病的老年人进行了横断面相关调查,采用分层随机抽样方法绘制。自我报告测量用于评估死亡焦虑,心理健康,和成功的衰老。据报道,老年人中死亡焦虑的患病率很高。这些老年人的心理健康和成功衰老与死亡焦虑显著负相关。Further,死亡焦虑对患有慢性疾病的老年人的心理健康和成功衰老具有显著的预测价值.研究结果强烈主张并呼吁对患有慢性病的老年人进行及时的干预计划,以减少他们的死亡焦虑,以增强心理健康并促进成功衰老。
    Comorbidities due to aging and the COVID-19 pandemic together are expected to cause death anxiety among older adults. This study aimed to assess the prevalence of death anxiety and its impact on psychological well-being and successful aging of older adults with chronic illness. A cross-sectional correlational survey was conducted on 79 older adults with chronic illness, drawn with a stratified random sampling method. Self-report measures were used to assess death anxiety, psychological well-being, and successful aging. A high prevalence of death anxiety was reported among older adults. Psychological well-being and successful aging in these older adults were significantly and negatively associated with death anxiety. Further, death anxiety showed substantial predictive valence for psychological well-being and successful aging of older adults with chronic illness. Findings strongly advocate and call for timely intervention programs for chronically ill older adults to reduce their death anxiety for enhanced psychological well-being and promote successful aging.
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  • 文章类型: Journal Article
    目的:研究衰老中韧性表型的决定因素,作为认知的维持,物理,和心理健康在非常老的人(80+),我们调查了主要的韧性增强因素的结构和相互关联的影响,通常在不同的研究领域进行研究。
    方法:参与者是未参加第五波InveCe的痴呆的老年人。基于Ab人群的队列研究(83-87岁)。多维评估包括血液采样,社会和生活方式调查,老年和神经心理学评估。我们将有弹性的个体归类为表现出正常的认知,功能独立,和心理健康。首先,我们进行了探索性因素分析(EFA)来检查相关认知的潜在结构,生活方式,物理,和心理韧性增强因素。将获得的因素作为弹性表型的预测因子纳入逻辑回归模型,控制社会人口统计学和累积暴露于身体和心理社会压力源,包括COVID-19感染。
    结果:在404名注册参与者中,153(38%)表现出弹性表型。EFA导致6个因素的识别(差异的59%):认知储备,情感储备,不安全的附件,当前的生活方式,实物储备,和回避的依恋。在这些因素中,认知储备,情感储备,和当前的生活方式显著和独立预测的弹性状态,控制与年龄相关的应激源和COVID-19感染的累积暴露。
    结论:我们的研究结果表明,即使在很老的时候,早期和晚期可改变的因素都会影响个体适应衰老过程的能力,从而证实了在老年人口改善健康结果的生命历程方法的重要性.
    OBJECTIVE: To investigate the determinants of resilience phenotype in aging, operationalized as the maintenance of cognitive, physical, and psychological health in very old individuals (80+), we investigated the structure and interrelated impact of the main resilience-enhancing factors, which are usually studied in separate research fields.
    METHODS: Participants were older adults without dementia recruited for the fifth wave of the InveCe.Ab population-based cohort study (aged 83-87 years). Multidimensional evaluation comprised blood sampling, social and lifestyle survey, geriatric and neuropsychological assessment. We classified resilient individuals as displaying normal cognition, functional independence, and mental health. First, we performed exploratory factor analysis (EFA) to examine the underlying structure of the relevant cognitive, lifestyle, physical, and psychological resilience-enhancing factors. The factors obtained were included as predictors of the resilience phenotype in the logistic regression model, controlling for sociodemographic and cumulative exposure to physical and psychosocial stressors, including COVID-19 infection.
    RESULTS: Among the 404 enrolled participants, 153 (38%) exhibited the resilience phenotype. EFA resulted in the identification of 6 factors (59% of variance): cognitive reserve, affective reserve, insecure attachment, current lifestyle, physical reserve, and avoidant attachment. Among these factors, cognitive reserve, affective reserve, and current lifestyle significantly and independently predicted resilience status, controlling for cumulative exposure to age-related stressors and COVID-19 infection.
    CONCLUSIONS: Our findings showed that, even in very old age, both early and late life modifiable factors affect individuals\' ability to adapt to the aging process, thus confirming the importance of a life-course approach to improve health outcomes in the aged population.
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  • 文章类型: Journal Article
    成功的认知衰老通常被认为是对病理积累的抵抗的结果,抵御病理性积累的影响,或者两者的某种组合。虽然在典型的老龄化人群中发现了韧性的证据,最古老的老人为我们提供了一个独特的窗口,了解病理积累在影响认知中的作用。这里,我们旨在利用阿尔茨海默病神经影像学计划(ADNI年龄:60-89岁)和90+研究(年龄:90-101岁)的数据,评估老年组淀粉样蛋白和tau指标的组间差异.此外,使用ADNI数据集,我们对区域扣带AV-45SUVR进行了探索性分析,以评估特定区域的淀粉样蛋白负荷是否与顶级认知表现(TCP)相关.与文献一致,结果表明,淀粉样蛋白SUVR在区域和整个皮质中都没有组间差异。对于具有AV-1451的tau,我们还观察到Braak复合SUVR没有差异。有趣的是,这些关系一直存在于最古老的时代。这表明,在整个衰老过程中,最高认知表现并不反映对淀粉样蛋白和tau负担的抵抗力,但其他机制可能与防止淀粉样蛋白和tau蛋白相关的神经变性有关。
    Successful cognitive aging is often thought to result from resistance to the accumulation of pathology, resilience to the effects of pathological accumulation, or some combination of the two. While evidence for resilience has been found in typical aging populations, the oldest-old provide us with a unique window into the role of pathological accumulation in impacting cognition. Here, we aimed to assess group differences in measures of amyloid and tau across older age groups using data from the Alzheimer\'s Disease Neuroimaging Initiative (ADNI age: 60-89) and The 90+ Study (age: 90-101). Additionally, using the ADNI dataset, we performed exploratory analyses of regional cingulate AV-45 SUVRs to assess if amyloid load in particular areas was associated with Top Cognitive Performance (TCP). Consistent with the literature, results showed no group differences in amyloid SUVRs both regionally and in the whole cortex. For tau with AV-1451, we also observed no differences in Braak composite SUVRs. Interestingly, these relationships persisted in the oldest-old. This indicates that Top Cognitive Performance throughout aging does not reflect resistance to amyloid and tau burden, but that other mechanisms may be associated with protection against amyloid and tau related neurodegeneration.
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  • 文章类型: Journal Article
    了解高阶神经认知网络的功能连通性(FC)与年龄相关的认知能力下降之间的关系是一个复杂且不断发展的研究领域。FC的减少与阿尔茨海默病和相关痴呆(ADRD)患者的认知能力下降有关。然而,在典型的认知衰老中,FC的贡献并不那么简单.一些研究表明,神经认知网络中相对稳健的FC将异常成功的认知衰老与平均衰老区分开来,而其他人没有。数据处理的方法学局限性和“成功老化”定义的不同可能是迄今为止结果不一致的原因。本研究旨在通过优化的MRI方法来解决以前的局限性,以检查已建立的SuperAging表型中的FC,根据年龄和认知表现定义为80岁及以上的个体,其情景记忆表现等于或优于50至60岁。使用静息状态功能MRI(rs-fMRI)从一次访问中比较了24个SuperAgers和16个认知平均老年对照(OAC)的大规模神经认知网络的网络内和网络间FC。群体分类是根据情景记忆的度量确定的,执行功能,口头流畅性和图片命名。纳入标准要求两次访问的认知状态稳定。首先,我们从一个常见的地图集分组中调查了七个静息态网络内部和之间的FC。还比较了组间网络隔离的单独指数。第二,我们研究了默认模式网络(DMN)的六个子组件之间的FC,ADRD患者的神经认知网络通常与记忆表现相关,并被破坏。对于每个分析,使用双样本独立t检验对各组进行比较,并对多重比较进行校正。在包括年龄在内的人口统计学特征上没有显著的组间差异,性和教育。在集团层面,网络内FC,网络间FC,和七个大规模网络的隔离测量,包括DMN的子组件,不是认知平均衰老和超衰老表型之间的主要区别。因此,大型网络内部或之间的FC似乎不是SuperAgers中观察到的出色内存性能的主要驱动因素。这些结果对于区分与认知衰老相关的FC变化与与ADRD相关的FC变化的作用具有相关性。
    Understanding the relationship between functional connectivity (FC) of higher-order neurocognitive networks and age-related cognitive decline is a complex and evolving field of research. Decreases in FC have been associated with cognitive decline in persons with Alzheimer\'s disease and related dementias (ADRD). However, the contributions of FC have been less straightforward in typical cognitive aging. Some investigations suggest relatively robust FC within neurocognitive networks differentiates unusually successful cognitive aging from average aging, while others do not. Methodologic limitations in data processing and varying definitions of \'successful aging\' may have contributed to the inconsistent results to date. The current study seeks to address previous limitations by optimized MRI methods to examine FC in the well-established SuperAging phenotype, defined by age and cognitive performance as individuals 80 and older with episodic memory performance equal to or better than 50-to-60-year-olds. Within- and between-network FC of large-scale neurocognitive networks were compared between 24 SuperAgers and 16 cognitively average older-aged control (OACs) with stable cognitive profiles using resting-state functional MRI (rs-fMRI) from a single visit. Group classification was determined based on measures of episodic memory, executive functioning, verbal fluency and picture naming. Inclusion criteria required stable cognitive status across two visits. First, we investigated the FC within and between seven resting-state networks from a common atlas parcellation. A separate index of network segregation was also compared between groups. Second, we investigated the FC between six subcomponents of the default mode network (DMN), the neurocognitive network commonly associated with memory performance and disrupted in persons with ADRD. For each analysis, FCs were compared across groups using two-sample independent t-tests and corrected for multiple comparisons. There were no significant between-group differences in demographic characteristics including age, sex and education. At the group-level, within-network FC, between-network FC, and segregation measurements of seven large-scale networks, including subcomponents of the DMN, were not a primary differentiator between cognitively average aging and SuperAging phenotypes. Thus, FC within or between large-scale networks does not appear to be a primary driver of the exceptional memory performance observed in SuperAgers. These results have relevance for differentiating the role of FC changes associated with cognitive aging from those associated with ADRD.
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