背景:本研究分析了国家自然科学基金委员会(NSFC)在1986年至2022年之间提供的心脏移植资金。研究结果为心脏移植研究提供了客观科学的参考。
方法:使用CiteSpace可视化呈现心脏移植研究中的关键词。
结果:从1986年到2022年,NFSC支付了1.1768亿日元,资助了259个与心脏移植有关的项目。湖北,上海,北京,广东,黑龙江获得的资金最多。普通和青年科学基金项目分别占58.69%和30.50%,分别。主要学科范畴是器官移植和移植免疫,占40.93%。研究热点包括“免疫耐受,“\”拒绝反应,\"\"t细胞\"\"树突状细胞,\"\"干细胞,“和”移植耐受性。“研究重点是”排斥反应,心脏衰竭,“\”免疫耐受,心脏移植,\"\"干细胞,“\”抑制细胞,\"\"树突状细胞,扩张型心肌病,\"和\"t单元格。“在过去的5年里,研究前沿有针对性的“移植耐受,缺血再灌注损伤,“和”心脏移植。
结论:国家自然科学基金对心脏移植研究的持续资助促进了学科的发展和人才的培养。新技术(例如,人造心脏和供体维护)对心脏移植研究提出了新的要求。
This study analyzes heart transplantation funding provided by the National Natural Science Foundation of China (NSFC) between 1986 and 2022. The findings offer an objective and scientific reference for heart transplantation research.
CiteSpace visualization was used to present keywords in heart transplantation research.
From 1986 to 2022, the NFSC disbursed ¥117.68 million to fund 259 projects related to heart transplantation. Hubei, Shanghai, Beijing, Guangdong, and Heilongjiang received the most funding. General and youth science fund projects accounted for 58.69% and 30.50%, respectively. The main discipline category was organ transplantation and transplantation immunity, accounting for 40.93%. Research hotspots included \"immune tolerance,\" \"rejection reaction,\" \"t cell\" \"dendritic cell,\" \"stem cell,\" and \"transplantation tolerance.\" Research foci were \"rejection reaction,\" \"heart failure,\" \"immune tolerance,\" \"heart transplantation,\" \"stem cell,\" \"suppressor cell,\" \"dendritic cell,\" \"dilated cardiomyopathy,\" and \"t cell.\" In the past 5 years, the research frontier has targeted \"transplantation tolerance,\" \"ischemia-reperfusion injury,\" and \"heart transplantation.\"
Continuous NSFC funding for heart transplantation research has promoted the development of disciplines and cultivation of talent. Novel technologies (e.g., artificial hearts and donor maintenance) have generated new requirements for heart transplantation research.