Becker's nevus

贝克尔痣
  • 文章类型: Case Reports
    贝克尔痣的卵泡变异体是一个报道不足的实体。我们介绍了7例患者中罕见的滤泡Becker痣的发生,通过皮肤镜检查和组织病理学检查证实。皮肤镜检查显示卵泡周围色素沉着不足,周围有明确定义的网状色素沉着,临床上与卵泡中心性黄斑的存在相对应。组织学显示毛囊周围突出的基底和基底上黑化,对应于在皮肤镜上看到的明确定义的网状色素沉着。然而,黑化不会沿着卵泡上皮的整个长度延伸,从而在皮肤镜检查中导致卵泡周围色素沉着不足。虽然活检是确证的,通常没有必要。
    The follicular variant of Becker\'s nevus is an under-reported entity. We present the rare occurrence of follicular Becker\'s nevus in 7 patients, confirmed through dermoscopy and histopathological examination. Dermoscopy shows perifollicular hypopigmentation surrounded by a well-defined net-like pigmentation corresponding clinically to the presence of folliculocentric macules. Histology shows prominent basal and suprabasal melanization surrounding the follicle, corresponding to well-defined net-like pigmentation seen on dermoscopy. However, the melanization does not extend along the entire length of the follicular epithelium leading to perifollicular hypopigmentation on dermoscopy. Though biopsy is confirmatory, it is not usually necessary.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Case Reports
    自出生以来,单侧的面部色素沉着过度病变是一种罕见且具有挑战性的皮肤病学异常,可能是遗传和非遗传的。本文旨在提供病因的详尽概述,临床表现,鉴别诊断,以及这些先天性病变的管理策略。单侧面部色素沉着过度病变可由多种情况引起,如先天性黑素细胞痣,贝克尔的痣,太田痣,线形表皮痣,和咖啡-au-lait黄斑。准确的诊断需要细致的检查,皮肤镜,和组织病理学评估。观察,局部治疗,手术切除,和激光治疗是可用的治疗选择之一。治疗决定应受到病变特征等因素的影响,美学问题,和患者偏好。长期监督和社会心理支持是综合治理不可或缺的要素。我们介绍了一个12岁的患者,其面部右侧的色素沉着病变逐渐增加,自出生以来就存在一个间歇性的正常皮肤区域。皮肤镜检查揭示了一个不规则的,深棕色颜料网络,组织病理学评估显示真皮中黑素细胞数量增加。此案例突出了此类病变的诊断挑战,并强调了多学科方法对准确评估和管理的重要性。本文旨在涵盖自出生以来有关单侧面部色素沉着过度病变的现有知识空白,并指导未来的诊断和治疗干预研究工作。
    Facial hyperpigmented lesions that are unilateral are a rare and challenging dermatological anomaly since birth which can be genetic and non-genetic. This paper seeks to provide an exhaustive overview of the etiology, clinical presentation, differential diagnosis, and management strategies for these congenital lesions. Unilateral facial hyperpigmented lesions can be caused by a number of conditions, such as congenital melanocytic nevi, Becker\'s nevus, nevus of Ota, linear epidermal nevi, and café-au-lait macules. Accurate diagnosis requires meticulous examination, dermoscopy, and histopathological evaluation. Observation, topical therapies, surgical excision, and laser therapy are among the available treatment options. Treatment decisions should be influenced by factors such as lesion characteristics, aesthetic concerns, and patient preferences. Long-term supervision and psychosocial support are indispensable elements of comprehensive management. We present a case of a 12-year-old patient with a progressively growing hyperpigmented lesion on the right side of the face, present since birth with an intermittent area of normal skin in between. Dermoscopy unveiled an irregular, dark brown pigment network, and histopathological evaluation showed an increased number of melanocytes in the dermis. This case highlights the diagnostic challenges of such lesions and underscores the significance of a multidisciplinary approach for accurate evaluation and management. This paper aims to cover existing knowledge gaps regarding unilateral facial hyperpigmented lesions since birth and direct future research efforts for diagnostic and therapeutic interventions.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    痣是一组黑素细胞,它们一起生长,在皮肤上形成良性生长。通常是黑色病变,可能从皮肤突出。Becker痣是一种先天性或获得性色素沉着过度病变。随着时间的推移,色素沉着和异常高的头发生长可能会变得更暗。贝克尔的痣,可以互换称为贝克尔黑变病,是一种罕见的疾病,通常由男性出现。以下病例是一名21岁的男性,他的右臂上有色素沉着过度的病变。病变始于16岁,大小逐渐增加;它累及右肘关节的屈肌表面,并显示多毛症,边缘不规则。在检查中,顶部的真皮含有黑色素细胞,基底层色素沉着过多。根据临床表现和检查,贝克尔的痣被诊断出来了.
    Nevus is a group of melanocytes that grow together to form a benign growth on the skin. It is often a black lesion that may protrude from the skin. Becker\'s nevus is a hyperpigmented lesion that presents congenitally or is acquired. The pigmentation and unusually high hair growth might grow darker with time. Becker\'s nevus, which can interchangeably be called Becker\'s melanosis, is a rare disease usually presented by men. The following case is of a 21-year-old male who presented with a hyperpigmented lesion on his right arm. The lesion started at age 16 and increased in size gradually; it involved the flexor surface of the right elbow joint and showed hypertrichosis with irregular margins. On examination, the top dermis contained melanophages, and the basal layer was hyperpigmented. Based on clinical appearance and examination, Becker\'s nevus was diagnosed.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    目的:评估1927-nm激光激光分割治疗Becker痣的疗效和安全性。
    方法:对采用1927nm激光点阵的Becker痣患者进行回顾性分析。根据医生对前后照片的全球评估,每季度确定一次减轻等级(I:<25%;II:25%-50%;III:51%-75%;IV:>75%用于明显的减轻)。使用10位皮肤科医生之间的观察者内部和观察者之间的一致性分析进行分级验证,以确定一致性百分比和组内相关系数。I级和II级被分类为治疗失败。
    结果:共招募21名患者进行分析。平均每个患者的治疗次数为2.1次。共有13名患者获得了成功的结果(III级和IV级),而8名患者经历了治疗失败(I级和II级)。部分复发和邻近皮肤短暂色素沉着不足是主要不良反应。只有一名患者报告痣恶化。评估者对结果的总体一致性从“非常好”到“优秀”,“和组内相关系数,kappa,是0.8
    结论:1927nm激光激光可以有效改善Becker痣的色素并达到可接受的美容效果。然而,需要在这方面进行进一步的研究,以改进和优化结果。
    To assess the efficacy and safety of a 1927-nm fractional thulium fiber laser treatment for Becker\'s nevus.
    A retrospective analysis of patients with Becker\'s nevus who were treated with a 1927-nm fractional thulium fiber laser was conducted. Grading for lightening was set quarterly by physician global assessment of the pre- and postphotographs (I: <25%; II: 25%-50%; III: 51%-75%; and IV: >75% for marked lightening). Grading validation was exercised using intra- and interobserver agreement analysis among 10 dermatologists to determine the percent of agreement and the intraclass correlation coefficient. Grades I and II were classified as treatment failure.
    A total of 21 patients were recruited for analysis. The average number of treatment sessions was 2.1 per patient. A total of 13 patients achieved successful outcomes (grades III and IV) while 8 patients experienced treatment failure (grades I and II). Partial recurrence and transient hypopigmentation on adjacent skin were the main adverse effects. Only one patient reported worsening of the nevus. Overall agreement among the raters for the outcomes was graded from \"very good\" to \"excellent,\" and the intraclass correlation coefficient, kappa, was 0.8.
    A 1927-nm fractional thulium fiber laser may be effective to ameliorate the pigment of Becker\'s nevus and achieve acceptable cosmetic outcomes. However, further studies are required in this area to improve and optimize the results.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Case Reports
    目的:Becker痣是一种美容上令人讨厌的良性错构瘤,通常与基底层色素沉着和多毛症有关。我们在此介绍了最大的病例系列,这些病例描述了1550nm非烧蚀性分数表面置换和激光脱毛(长脉冲掺钕钇铝石榴石或翠绿宝石)联合治疗Becker痣的治疗参数和临床结果。这也是Fitzpatrick皮肤V型和VI型Becker痣的最大病例系列激光治疗。
    方法:我们对2016年至2021年接受治疗的患者进行了回顾性分析。临床照片由三位独立的医生使用5点视觉模拟量表进行评分。
    结果:12名患者(平均年龄:24.8岁,Fitzpatrick皮肤III-VI型)治疗Becker痣的面部(4)或躯干和/或四肢(8)。4例患者为FitzpatrickV型或VI型皮肤。平均而言,患者每1-4个月接受5.3次治疗.12名患者中有10名在当天非消融性局部表面置换之前同时进行了激光脱毛(n=7,长脉冲1064nm掺钕钇铝石榴石,n=3,长脉冲755nm翠绿宝石)。每种方式的治疗次数取决于患者对色素沉着过度和多毛症改善的满意度。在后续行动中,从6到40周(平均10.5周),患者的平均改善评分为51%-75%.两组均未发生长期不良事件。局限性包括样本量小和缺乏长期随访。
    结论:1550nm非消融性分数表面置换和激光脱毛组合在减少与Becker痣相关的色素沉着和多毛症的美容方面是安全有效的,包括那些与Fitzpatrick皮肤类型V和VI。
    Becker\'s nevus is a cosmetically bothersome benign hamartoma typically associated with basal layer hyperpigmentation and hypertrichosis. We herein present the largest case series characterizing treatment parameters and clinical outcomes of combined 1550 nm non-ablative fractional resurfacing and laser hair removal (long-pulsed neodymium-doped yttrium aluminum garnet or alexandrite) in the treatment of Becker\'s nevus. This is also the largest case series of laser treatment of Becker\'s nevus in Fitzpatrick skin types V and VI.
    We performed a retrospective review of patients treated between 2016 and 2021. Clinical photographs were graded by three independent physicians using a 5-point visual analog scale.
    Twelve patients (mean age: 24.8 years, Fitzpatrick skin types III-VI) were treated for Becker\'s nevus on the face (4) or the trunk and/or extremities (8). Four patients were Fitzpatrick skin types V or VI. On average, patients received 5.3 treatments in 1-4-month intervals. Ten of the 12 patients had concomitant laser hair removal preceding same-day non-ablative fractional resurfacing (n = 7 with long-pulsed 1064 nm neodymium-doped yttrium aluminum garnet and n = 3 with long-pulsed 755 nm alexandrite). The number of treatments with each modality was determined by patient satisfaction with improvement in hyperpigmentation and hypertrichosis. At follow-up, which ranged from 6 to 40 weeks (mean 10.5 weeks), patients were given a mean improvement score of 51%-75%. No long-term adverse events were encountered in either group. Limitations include a small sample size and a lack of long-term follow-up.
    Combination 1550 nm non-ablative fractional resurfacing and laser hair removal is safe and efficacious in the cosmetic reduction of hyperpigmentation and hypertrichosis associated with Becker\'s nevus, including those with Fitzpatrick skin types V and VI.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    贝克尔的痣(BN)表现为色素沉着过度,有时在胸部和肩膀上出现多毛斑块/斑块,属于良性皮肤错构瘤。BN具有网状脊的伸长和融合,角化堵塞,皮脂腺增生,平滑肌增生,和组织学上基底/上层的色素沉着过度。本文重点介绍了与BN的发病机制和治疗方案有关的所有问题。根据目前的研究,合子后ACTB突变可诱导BN和Becker痣综合征(BNS)。尽管使用了几种治疗策略来治疗BN的色素性和多毛性方面,目前还没有确定明确的标准治疗方法,需要进一步的研究来更好地教育BN护理。
    Becker\'s nevus (BN) manifests as a hyperpigmented, sometimes hypertrichotic plaque/patch over the chest and shoulder, and it is in the category of benign cutaneous hamartomas. BN has elongation and fusion of the rete ridge, keratotic plugging, sebaceous hyperplasia, smooth muscle hyperplasia, and hyperpigmentation of the basal/suprabasal layer histologically. This article highlights all issues involved in pathogenesis and treatment options of BN. According to current research, postzygotic ACTB mutations induce BN and Becker\'s nevus syndrome (BNS). Although several therapy strategies were utilized to treat the pigmentary and hypertrichotic aspects of BN, no definitive standard treatment was identified to far, and further research is needed to better educate BN care.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Case Reports
    贝克尔痣(BN)是皮肤错构瘤病变之一,通常表现为获得性,上躯干的单个单侧色素毛斑,肩胛骨区域,或上臂。在此,我们介绍一个13岁的女孩,具有多重获得性的BN的不寻常表现,色素性毛斑六个月,没有任何肌肉骨骼或发育参与。在仔细查阅文献后,据我们所知,这是伊朗在这方面的第一例。
    Becker\'s nevus (BN) is one of the cutaneous hamartomatous lesions that often presents as an acquired, single unilateral pigmented hairy patch on the upper trunk, scapular region, or upper arm. Hereby we introduce a 13-year-old girl with the unusual manifestation of BN with multiple acquired, pigmented hairy patches for six months without any musculoskeletal or developmental involvements. After carefully reviewing the literature, to the best of our knowledge, this is the first case in this regard in Iran.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • DOI:
    文章类型: Case Reports
    贝克尔痣是一种主要的表皮黑色素沉着症,通常出现在青春期,虽然儿童期病例较少见。先天性病例很少报道。痣通常是单侧的,色素沉着增加,其特征是多毛症。它通常表现为背面的补丁,上肢近端,手臂和上躯干。贝克尔的痣表现为双侧不对称斑块是罕见的。报告一例23岁男性背部双侧色素沉着过度斑块。组织学检查建立了贝克尔痣的临床假设。
    Becker\'s nevus is a main epidermal hypermelanotic condition that usually presents in adolescence, though childhood cases are seen less commonly. Congenital cases have been rarely reported. Nevus is usually unilateral having increased pigmentation and is characterized by hypertrichosis. It usually presents as a patch on back, proximal upper extremities, arms and upper trunk. Becker\'s Nevus presenting as bilateral asymmetrical patch is rare. A case of 23 year\'s old male with bilateral hyperpigmentad patch over the back has been reported. The histological exams established the clinical hypothesis of Becker\'s Nevus.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Case Reports
    Becker\'s nevus (BN) is an acquired unilateral hyperpigmented hairy macule, whereas morphea is a chronic connective tissue disease of unknown etiology, characterized by skin thickening with increased quantities of collagen in the indurated lesion, usually involving the upper trunk and proximal extremity. The occurrence of both disease in the same anatomical site and individual was not reported previously. We report this rare case in a 17-year-old, Indian girl and was diagnosed after clinical histopathology and dermoscopic correlation. Morphea can be an interesting incidental occurrence within a large plaque of BN.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Sci-hub)

       PDF(Pubmed)

  • 文章类型: Journal Article
    BACKGROUND: Becker\'s nevus is a common skin disorder. Lasers and light instruments are the major modalities for the treatment of Becker\'s nevus, but the outcomes were mixed.
    OBJECTIVE: To evaluate the efficacy of the intense pulsed light for Becker\'s nevus in a large Chinese cohort.
    METHODS: We retrospectively analyzed the efficacy of the intense pulsed light for Becker\'s nevus in a single center.
    RESULTS: A total of 45 patients, including 26 males and 19 females (male to female ratio = 1.4), aged 5-42 years, were included in this analysis. Twenty-seven patients (60%) were with hypertrichosis. Treatments with intense pulsed light resulted in over 75% improvements in pigmentation and hair density in 1 and 2 cases, respectively. One patient displayed 51%-75% reductions in hair density. The rest displayed ≤50% improvements in pigmentation and hair density. Recurrence occurred in all cases within 6 months after the last treatment. Adverse reactions were temporary and mild hypopigmentation, hyperpigmentation, hypertrophic scar, pain, and erythema.
    CONCLUSIONS: Intense pulsed light does not exhibit long-term benefits for Becker\'s nevus. Further studies in the large cohort are still required to validate the present results. Moreover, whether changes in the treatment parameters can improve the efficacy of intense pulsed light remains to be explored.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Sci-hub)

公众号