Becker's nevus

贝克尔痣
  • 文章类型: Case Reports
    自出生以来,单侧的面部色素沉着过度病变是一种罕见且具有挑战性的皮肤病学异常,可能是遗传和非遗传的。本文旨在提供病因的详尽概述,临床表现,鉴别诊断,以及这些先天性病变的管理策略。单侧面部色素沉着过度病变可由多种情况引起,如先天性黑素细胞痣,贝克尔的痣,太田痣,线形表皮痣,和咖啡-au-lait黄斑。准确的诊断需要细致的检查,皮肤镜,和组织病理学评估。观察,局部治疗,手术切除,和激光治疗是可用的治疗选择之一。治疗决定应受到病变特征等因素的影响,美学问题,和患者偏好。长期监督和社会心理支持是综合治理不可或缺的要素。我们介绍了一个12岁的患者,其面部右侧的色素沉着病变逐渐增加,自出生以来就存在一个间歇性的正常皮肤区域。皮肤镜检查揭示了一个不规则的,深棕色颜料网络,组织病理学评估显示真皮中黑素细胞数量增加。此案例突出了此类病变的诊断挑战,并强调了多学科方法对准确评估和管理的重要性。本文旨在涵盖自出生以来有关单侧面部色素沉着过度病变的现有知识空白,并指导未来的诊断和治疗干预研究工作。
    Facial hyperpigmented lesions that are unilateral are a rare and challenging dermatological anomaly since birth which can be genetic and non-genetic. This paper seeks to provide an exhaustive overview of the etiology, clinical presentation, differential diagnosis, and management strategies for these congenital lesions. Unilateral facial hyperpigmented lesions can be caused by a number of conditions, such as congenital melanocytic nevi, Becker\'s nevus, nevus of Ota, linear epidermal nevi, and café-au-lait macules. Accurate diagnosis requires meticulous examination, dermoscopy, and histopathological evaluation. Observation, topical therapies, surgical excision, and laser therapy are among the available treatment options. Treatment decisions should be influenced by factors such as lesion characteristics, aesthetic concerns, and patient preferences. Long-term supervision and psychosocial support are indispensable elements of comprehensive management. We present a case of a 12-year-old patient with a progressively growing hyperpigmented lesion on the right side of the face, present since birth with an intermittent area of normal skin in between. Dermoscopy unveiled an irregular, dark brown pigment network, and histopathological evaluation showed an increased number of melanocytes in the dermis. This case highlights the diagnostic challenges of such lesions and underscores the significance of a multidisciplinary approach for accurate evaluation and management. This paper aims to cover existing knowledge gaps regarding unilateral facial hyperpigmented lesions since birth and direct future research efforts for diagnostic and therapeutic interventions.
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  • 文章类型: Case Reports
    痣是一组黑素细胞,它们一起生长,在皮肤上形成良性生长。通常是黑色病变,可能从皮肤突出。Becker痣是一种先天性或获得性色素沉着过度病变。随着时间的推移,色素沉着和异常高的头发生长可能会变得更暗。贝克尔的痣,可以互换称为贝克尔黑变病,是一种罕见的疾病,通常由男性出现。以下病例是一名21岁的男性,他的右臂上有色素沉着过度的病变。病变始于16岁,大小逐渐增加;它累及右肘关节的屈肌表面,并显示多毛症,边缘不规则。在检查中,顶部的真皮含有黑色素细胞,基底层色素沉着过多。根据临床表现和检查,贝克尔的痣被诊断出来了.
    Nevus is a group of melanocytes that grow together to form a benign growth on the skin. It is often a black lesion that may protrude from the skin. Becker\'s nevus is a hyperpigmented lesion that presents congenitally or is acquired. The pigmentation and unusually high hair growth might grow darker with time. Becker\'s nevus, which can interchangeably be called Becker\'s melanosis, is a rare disease usually presented by men. The following case is of a 21-year-old male who presented with a hyperpigmented lesion on his right arm. The lesion started at age 16 and increased in size gradually; it involved the flexor surface of the right elbow joint and showed hypertrichosis with irregular margins. On examination, the top dermis contained melanophages, and the basal layer was hyperpigmented. Based on clinical appearance and examination, Becker\'s nevus was diagnosed.
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  • 文章类型: Case Reports
    贝克尔痣(BN)是皮肤错构瘤病变之一,通常表现为获得性,上躯干的单个单侧色素毛斑,肩胛骨区域,或上臂。在此,我们介绍一个13岁的女孩,具有多重获得性的BN的不寻常表现,色素性毛斑六个月,没有任何肌肉骨骼或发育参与。在仔细查阅文献后,据我们所知,这是伊朗在这方面的第一例。
    Becker\'s nevus (BN) is one of the cutaneous hamartomatous lesions that often presents as an acquired, single unilateral pigmented hairy patch on the upper trunk, scapular region, or upper arm. Hereby we introduce a 13-year-old girl with the unusual manifestation of BN with multiple acquired, pigmented hairy patches for six months without any musculoskeletal or developmental involvements. After carefully reviewing the literature, to the best of our knowledge, this is the first case in this regard in Iran.
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  • 文章类型: Case Reports
    Becker\'s nevus (BN) is an acquired unilateral hyperpigmented hairy macule, whereas morphea is a chronic connective tissue disease of unknown etiology, characterized by skin thickening with increased quantities of collagen in the indurated lesion, usually involving the upper trunk and proximal extremity. The occurrence of both disease in the same anatomical site and individual was not reported previously. We report this rare case in a 17-year-old, Indian girl and was diagnosed after clinical histopathology and dermoscopic correlation. Morphea can be an interesting incidental occurrence within a large plaque of BN.
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  • 文章类型: Journal Article
    BACKGROUND: Becker\'s nevus is a common skin disorder. Lasers and light instruments are the major modalities for the treatment of Becker\'s nevus, but the outcomes were mixed.
    OBJECTIVE: To evaluate the efficacy of the intense pulsed light for Becker\'s nevus in a large Chinese cohort.
    METHODS: We retrospectively analyzed the efficacy of the intense pulsed light for Becker\'s nevus in a single center.
    RESULTS: A total of 45 patients, including 26 males and 19 females (male to female ratio = 1.4), aged 5-42 years, were included in this analysis. Twenty-seven patients (60%) were with hypertrichosis. Treatments with intense pulsed light resulted in over 75% improvements in pigmentation and hair density in 1 and 2 cases, respectively. One patient displayed 51%-75% reductions in hair density. The rest displayed ≤50% improvements in pigmentation and hair density. Recurrence occurred in all cases within 6 months after the last treatment. Adverse reactions were temporary and mild hypopigmentation, hyperpigmentation, hypertrophic scar, pain, and erythema.
    CONCLUSIONS: Intense pulsed light does not exhibit long-term benefits for Becker\'s nevus. Further studies in the large cohort are still required to validate the present results. Moreover, whether changes in the treatment parameters can improve the efficacy of intense pulsed light remains to be explored.
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  • 文章类型: Case Reports
    贝克尔的痣,也被称为色素毛状表皮痣,被描述为单方面的,毛茸茸的,浅至深棕色斑疹,轮廓清晰但边界不规则。Becker痣的病因尚不清楚。一些作者先前已经描述了滤泡周围的色素沉着。但是,尚未描述仅表现为滤泡性病变的Becker痣。我们正在报告一系列Becker痣伴滤泡性病变的患者。所有患者均经临床病理对照诊断。卵泡上皮可能在Becker痣的发病机制中起重要作用。
    Becker\'s nevus, also known as pigmented hairy epidermal nevus, is characteristically described as a unilateral, hairy, light to dark brown macule with sharply outlined but irregular border. The etiopathogenesis of Becker\'s nevus is still not clearly understood. Perifollicular pigmentation has been described earlier by some authors. But, Becker\'s nevus presenting exclusively with follicular lesions has not been described. We are reporting a series of patients of Becker\'s nevus with follicular lesions. The diagnosis in all the patients was made after clinicopathological correlation. Follicular epithelium may hold a significant role in the etiopathogenesis of Becker\'s nevus.
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  • 文章类型: Journal Article
    UNASSIGNED: Becker\'s Nevus (BN) is a benign hamartoma with an esthetically troublesome condition secondary to hyperpigmentation and hypertrichosis. Many treatment modalities have been utilized with variable outcomes.
    UNASSIGNED: To evaluate the efficacy and safety of intense pulsed light (IPL) in the treatment of BN.
    UNASSIGNED: IPL was used at filter of 590 nm, fluence of 18-22 J/cm2, double-pulse mode (pulse width of 3-10 ms, pulse delay of 20-30 ms) at 3-month intervals. Final evaluations were performed by physician global assessment and patient satisfaction. Side effects were monitored at each treatment session and follow-up visit.
    UNASSIGNED: Twenty-four patients (9 females, 15 males) with BN (16 hypertrichotic, 8 atrichotic) completed the study. The mean number of treatment sessions was 5 ± 2.17. The improvement in atrichotic BN group (4.87 ± 0.35) was significantly greater than that observed in hypertrichotic BN group (3.63 ± 0.89) (p = .001). Hair density simultaneously decreased with treatment in hypertrichotic BN. The mean satisfaction score was 5.75 ± 2.05 and 8 ± 0.93 in hypertrichotic and atrichotic BN groups respectively (p = .002). No repigmentation was noted during the follow-up period. No permanent side effects were observed.
    UNASSIGNED: IPL is an effective and well-tolerated treatment option for patients with hypertrichotic and atrichotic BN.
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  • 文章类型: Journal Article
    BACKGROUND: Patients with epidermal nevi strongly demand cosmetic improvement. Laser treatment appears appealing and is frequently used in clinical practice. Nevertheless, large series with long-term follow-up are missing, preventing definitive conclusions about its real benefit.
    OBJECTIVE: To evaluate the long-term effectiveness and safety of lasers for epidermal nevi.
    METHODS: Bicentric, retrospective, cohort study, including all patients treated with a laser for an epidermal nevus with more than a 1-year follow-up.
    RESULTS: Seventy patients were treated for different types of epidermal nevi, mostly with ablative lasers: 23 verrucous epidermal nevi, 16 nevi sebaceous, 26 Becker nevi, 2 inflammatory linear verrucous epidermal nevi, 1 smooth-muscle hamartoma, 1 rounded and velvety epidermal nevus, and 1 nevus lipomatosus superficialis. The follow-up period was a median of 37 months (range, 12-127 months). Better results, fewer recurrences, and higher patient satisfaction were noted in treatments for verrucous epidermal nevi than for nevi sebaceous. Q-switched lasers failed to show any degree of improvement in almost all patients with Becker nevus.
    CONCLUSIONS: The retrospective nature of the study.
    CONCLUSIONS: Ablative lasers can treat verrucous epidermal nevi with good long-term esthetic results but have limited long-term efficacy for nevus sebaceous. Q-switched lasers failed to improve Becker nevi.
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  • 文章类型: Case Reports
    Several dermatoses have been reported in association with Becker\'s nevus. Eczematous dermatitis associated with Becker\'s nevus is extremely rare, described in only two previous case reports. We report a case of 21-year-old male with recurrent eczema lesions which were always localized within the underlying Becker\'s nevus lesion. This case may be explained as a Wolf\'s isotopic response-like phenomenon.
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  • 文章类型: Journal Article
    BACKGROUND: Facial hypermelanosis is a significant cause of cosmetic disfigurement, social embarrassment and psychological morbidity affecting quality of life.
    OBJECTIVE: To study clinicoepidemlogic patterns of facial hypermelanoses among men.
    METHODS: Medical records of all adult males presenting with facial hypermelanoses were analyzed for this retrospective cross sectional study for demographic details, duration, cosmetic usage, sun exposure, drug intake, infections, systemic or cutaneous diseases, and family history of hypermelanotic dermatosis. Laboratory investigations and skin biopsy were performed when deemed necessary.
    RESULTS: These were 300 Indian men aged 18 to 74 (mean 37.35) years with 121 (40.3%) individuals aged 31-50 years. Various patterns of melasma in 230 (76.7%) patients were the major cause of facial hypermelanosis. Periorbital hypermelanosis was observed in 32 (10.7%), freckles and lentigens in 26 (8.7%), acanthosis nigricans in 12 (4%) and lichen planus pigmentosus in 10 (3.3%), pigmented cosmetic contact dermatitis in 7, and nevus of Ota in 6 persons. The 71 (30.8%) patients with melasma had a history of frequent sun exposure, 9 (3.9%) patients had systemic comorbidities. Family history of periorbital melanosis was present in 7 (21.8%), personal or family history of atopy in 5 (15.6%) patients. Acanthosis nigricans was associated with obesity in 9 (75%) of patients and with diabetes mellitus in 4 (33.3%) cases.
    CONCLUSIONS: Melasma, periorbital hypermelanosis, acanthosis nigricans and lichen planus pigmentosus remain the predominant causes for facial hypermelanosis in men.
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