背景:乙酰白藜芦醇(AC-Res),到目前为止,是有机地产生或作为植物防御系统的组成部分的强大的二苯乙烯植物抗毒素,是重要的植物酚类化学部分,并作为许多疾病的治疗选择进行了研究。由于其稳定性不足和相当大的构象刚度,AC-Res作为药物的效用是有限的。
目的:当前的评论文章概述了AC-Res的结构,他们的活动方法,以及这些分子管理的最新技术进步。可以想象得出AC-Res对感染细胞的细胞功能具有多种后果。
方法:本文的文献调查来自各种同行评审出版商发布的真实数据,这些出版商采用GoogleScholar和PubMedprioritizingScopus和WebofScience索引期刊作为搜索平台,专注于AC-Res药理作用,尤其是英语。
结果:尽管其广泛的生物和治疗应用,AC-Res已成为日益关注的来源。取决于研究人员,AC-Res具有防辐射功能,心脏保护,神经学,抗炎,和抗微生物潜力。它还具有抗癌和抗氧化特性。
结论:为了避免非特异性细胞毒性,优化工作目前正在强调基于纳米晶体的AC-Res的可能使用,纳米粒子和树枝状聚合物,和纳米晶体。最后,虽然在生物学中使用AC-Res还有很长的路要走,研究人员一致认为,如果他们继续探索它,AC-Res和类似部件将被认为是未来几年内各种事物的实际可能性。
BACKGROUND: Acetylresveratrol (AC-Res), to date, is a powerful stilbene phytoalexin generated organically or as a component of a plant\'s defensive system, is a significant plant phenolic chemical portion and is investigated as a therapy option for a number of disorders. Owing to its inadequate stabilisation and considerable conformation rigidity, the utility of AC-Res as a medication is limited.
OBJECTIVE: The current review article outlined the structure of AC-Res, their methods of activity, and the latest technological progress in the administration of these molecules. It is conceivable to deduce that AC-Res has a variety of consequences for the cellular functions of infected cells.
METHODS: The literature survey for the present article was gathered from the authentic data published by various peer-reviewed publishers employing Google Scholar and PubMedprioritizing Scopus and Web of Science indexed journals as the search platform focusing on AC-Res pharmacological actions, particularly in the English language.
RESULTS: Despite its extensive spectrum of biological and therapeutic applications, AC-Res has become a source of increasing concern. Depending on the researchers, AC-Res possesses radioprotective, cardioprotective, neurological, anti-inflammatory, and anti-microbial potential. It also has anti-cancer and antioxidant properties.
CONCLUSIONS: To avoid non-specific cytotoxicity, optimization efforts are presently emphasizing the possible usage of AC-Res based on nanocrystals, nanoparticles and dendrimers, and nanocrystals. Finally, while using AC-Res in biology is still a way off, researchers agree that if they continue to explore it, AC-Res and similar parts will be recognized as actual possibilities for a variety of things in the next years.