laryngology

喉科
  • 文章类型: Journal Article
    背景:在急诊科(ED),有预先组装的扁桃体出血托盘,用于治疗扁桃体切除术后出血和扁桃体周围脓肿。使用后,托盘被送到医疗器械再处理(MDR)部门进行净化,灭菌,和重组,所有这些都给医院和环境带来了巨大的成本。
    目的:该项目的目标是在1年内将扁桃体出血盘上不必要的器械减少30%,并报告相关成本和二氧化碳(CO2)排放量的节省。
    方法:这个质量改进项目是根据医疗保健改进研究所的改进模型制定的。对ED和耳鼻咽喉头颈外科工作人员和居民进行了调查,以确定扁桃体出血托盘上的哪些仪器被定期使用。根据结果,开发了一个新的托盘,并使用MDR数据和现有的CO2排放计算与旧托盘进行了比较。
    结果:托盘优化导致每年每个托盘的总成本从1092.63美元降低到330.21美元,将每个托盘的处理时间从12分钟减少到6-8分钟,新旧托盘的二氧化碳排放量从每年6.11千克减少到2.85千克,分别。总的来说,新的托盘包含一半数量的仪器,组装需要一半的时间,减少50%的二氧化碳排放量,并将在10年内为医院节省约10万美元。
    结论:医疗成本和环境可持续性是集体责任。手术和手术托盘的优化是一个简单的,有效,和可扩展的生态行动形式。
    BACKGROUND: In the emergency department (ED), there are pre-assembled tonsillar hemorrhage trays for management of post-tonsillectomy hemorrhage and peritonsillar abscess. After use, the tray is sent to the medical device reprocessing (MDR) department for decontamination, sterilization, and re-organization, all at a significant cost to the hospital and environment.
    OBJECTIVE: The goal of this project was to reduce unnecessary instruments on the tonsil hemorrhage tray by 30% by 1 year and report on the associated cost and carbon dioxide (CO2) emissions savings.
    METHODS: This quality improvement project was framed according to the Institute for Healthcare Improvement\'s Model for Improvement. ED and Otolaryngology-Head & Neck Surgery staff and residents were surveyed to determine which instruments on the tonsil hemorrhage trays were used regularly. Based on results, a new tray was developed and compared to the old tray using MDR data and existing CO2 emissions calculations.
    RESULTS: Tray optimization resulted in a total cost reduction from $1092.63 to $330.21 per tray per year, decreased processing time from 12 to 6-8 minutes per tray, and decreased CO2 emissions from 6.11 to 2.85 kg per year for the old versus new tray, respectively. Overall, the new tray contains half the number of instruments, takes half the time to assemble, produces 50% less CO2 emissions, and will save the hospital approximately $100,000 over 10 years.
    CONCLUSIONS: Healthcare costs and environmental sustainability are collective responsibilities. Surgical and procedure tray optimization is a simple, effective, and scalable form of eco-action.
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  • 文章类型: Journal Article
    人们越来越关注用于医学教育的高质量模拟模型的开发。尸体模型,虽然被认为更现实,可能很难获得,而且成本很高。三维(3D)打印的出现提供了低成本,可靠,和可重复的替代品。这项研究旨在比较3D打印与尸体模型在经皮注射喉成形术(TIL)训练中的实用性。
    采用了交叉设计的模拟课程。视频喉镜用于3D和尸体模型,以评估注入声带的准确性。进行了术前和术后调查,以1-10的Likert量表评估理解和舒适度。每个模型还在1-5李克特量表上对自我效能感进行了评估,保真度,和教育价值。
    调查前后的数据由15名耳鼻喉科住院医师和医学生完成。研讨会前的平均理解力和舒适度分别为3.7和2.2,与使用3D模型后的6.9和5.9(p<0.05)以及使用尸体模型后的6.4和4.7(p<0.05)相比。在比较3D和尸体模型时,在自我效能感方面没有观察到显著差异,保真度,和教育价值。
    使用3D和尸体模型后,理解和舒适度也有类似的平均增加。3D打印可以提供一个很好的辅助,最终可能替代医学教育中的动手尸体培训,特别是TIL。
    三级。
    UNASSIGNED: There is increasing focus on the development of high-quality simulation models for medical education. Cadaveric models, although considered more realistic, may be difficult to obtain and costly. The advent of three-dimensional (3D) printing has offered a low-cost, reliable, and reproducible alternative. This study sought to compare the utility of 3D-printed to cadaveric models for training in transcutaneous injection laryngoplasty (TIL).
    UNASSIGNED: A simulation course with a cross-over design was employed. Video laryngoscopes were utilized for both the 3D and cadaveric models to assess the accuracy of injection into the vocal fold. Pre-procedure and post-procedure surveys were administered to evaluate understanding and comfort level on a Likert scale of 1-10. Each model was also rated on a 1-5 Likert scale for self-efficacy, fidelity, and educational value.
    UNASSIGNED: Pre- and post-survey data were completed by 15 otolaryngology residents and medical students. Mean pre-seminar understanding and comfort level were 3.7 and 2.2, respectively, compared to 6.9 and 5.9 (p < .05) following use of the 3D model and 6.4 and 4.7 (p < .05) following use of the cadaver model. When comparing 3D and cadaveric models, no significant differences were observed regarding self-efficacy, fidelity, and educational value.
    UNASSIGNED: There was a similar mean increase in understanding and comfort following use of the 3D and cadaveric models. 3D-printing can provide an excellent adjunct to, and eventually a potential replacement for hands-on cadaveric training in medical education, particularly for TIL.
    UNASSIGNED: Level III.
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  • 文章类型: Journal Article
    本研究旨在对Reinke\'s水肿(RE)患者的水肿程度进行分类,并使用客观和主观评估方法检查其对其语音参数的影响。
    回顾性评估了2018年至2021年间诊断为RE的104例患者的客观和主观语音数据。RE分为4组(类型1、2、3和4)。评估包括电视喉镜检查,声学语音分析,和空气动力学测量,GRBAS,语音障碍索引-10(VHI-10),语音相关生活质量量表(V-RQOL)和反流中隔指数(RSI)。
    1型RE患者的平均年龄明显低于3-4型RE患者。尽管两组之间的声学和空气动力学参数没有显着差异,观察到F0和最大发声时间随着水肿程度的增加而减少。GRBASTotal,G,1型和2型的R得分明显低于3型和4型,1型S的得分也明显低于3型和4型。在VHI-10、V-RQOL、和RSI分数。
    已经观察到,随着RE严重程度的增加,语音感知和质量(尤其是类型3和4)受到负面影响。确定水肿的程度将指导临床医生规划介入阶段和随访阶段。
    UNASSIGNED: This study aimed to classify the degree of edema in patients with Reinke\'s edema (RE) and examine its impact on their voice parameters using both objective and subjective assessment methods.
    UNASSIGNED: Objective and subjective voice data of 104 patients diagnosed with RE between 2018 and 2021 were evaluated retrospectively. RE is classified into 4 groups (types 1, 2, 3, and 4). The evaluation included videolaryngostroboscopic examination, acoustic voice analysis, and aerodynamic measurements, GRBAS, Voice Handicap Index-10 (VHI-10), Voice-Related Quality of Life Scale (V-RQOL), and Reflux Septum Index (RSI).
    UNASSIGNED: Patients with type 1 RE had a significantly lower mean age than those with types 3-4. Although there were no significant differences in acoustic and aerodynamic parameters between the groups, it was observed that F0 and the maximum phonation time decreased as the degree of edema increased. The GRBASTotal, G, and R scores of types 1 and 2 were significantly lower than those of types 3 and 4, as were the scores of type 1 S. There were no statistically significant differences between the RE groups in terms of VHI-10, V-RQOL, and RSI scores.
    UNASSIGNED: It has been observed that as the severity of RE increases, voice perception and quality (especially types 3 and 4) are negatively affected. Determining the degree of edema will guide the clinician in both the planning of the intervention phase and the follow-up phase.
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  • 文章类型: Case Reports
    我们讨论了一种新的方法,通过直接喉镜检查结合内窥镜和显微喉镜技术切除1.5厘米大的索内神经鞘瘤。在直接喉镜检查期间,去除声带软组织内相对庞大的肿块可能是困难的手术视野可视化的次要挑战。我们描述了一种情况,其中通过内窥镜和显微喉镜联合技术通过直接喉镜清除了庞大的非典型梭形细胞神经鞘瘤。肿瘤阻塞了喉镜视野的40%。在这种情况下,一名44岁的女性出现在头颈部外科诊所,1.5年的进行性声音嘶哑。在纤维喉镜检查中,注意到一个肿块中介了正确的真实声带。患者接受手术,并在用Dedo喉镜插管和悬吊后,通过喉镜经口切除肿块,同时使用刚性和柔性内窥镜以及显微镜进行观察.虽然使用直接喉镜有时可以减少可视化,在某些情况下,可以对相对较大的喉部肿块进行手术切除,而无需经宫颈接近肿块。
    We discuss a novel approach to resecting a large 1.5 cm intracordal schwannoma via direct laryngoscopy with combined endoscopic and microlaryngoscopic techniques. Removing relatively bulky masses within the vocal cord soft tissue can be challenging secondary to difficult visualization of the operative field during direct laryngoscopy. We describe a case where a bulky atypical spindle cell schwannoma was removed via direct laryngoscopy via combined endoscopic and microlaryngoscopic techniques. The tumor obstructed 40% of the visual field of the laryngoscope. In this case, a 44-year-old female presented to the head and neck surgery clinic with 1.5 years of progressive hoarseness. On fiberoptic laryngoscopy, a mass was noted medializing the right true vocal cord. The patient was taken to surgery and after intubation and suspension with a Dedo laryngoscope, the mass was removed trans-orally through the laryngoscope with visualization using a combination of rigid and flexible endoscopy as well as with a microscope. Although visualization can sometimes be reduced using direct laryngoscopy, surgical excision of relatively large laryngeal masses can be performed in selected cases without the need to approach the masses trans-cervically.
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  • 文章类型: Journal Article
    2019年冠状病毒病(COVID-19)大流行的发作改变了整个医学的实践模式。这项研究的目的是评估COVID-19发病后喉科手术的体积和位置设置的变化。
    回顾性数据库队列研究。
    Reg-ENT注册表。
    2017年至2022年对接受了喉科手术的患者进行了回顾性审查,这些患者按服务场所代码“门诊手术”和“办公室”设置进行了分类。以2020年3月为临界点,该程序被指定为前COVID和COVID时间段。
    共有5989名患者接受了喉科手术。在COVID期间(n=3780)进行的手术比在COVID之前(n=2209)多42%。前COVID,在办公室和门诊手术设置之间的程序分布为70%(n=1546),而30%(663)。在COVID期间,这一比例分别上升到77%(n=2920)和23%(n=860),P=.9。在研究期间,与喉科手术相关的最常见诊断是声带麻痹47%(n=2831),发声障碍33%(n=1392),喉气管狭窄14%(n=838)。这些趋势在COVID前和COVID时间段都保持不变。大流行开始后,在接受喉科手术的患者中,喉气管狭窄的诊断增加了93%(n=284-549),发声障碍增加70%(n=520-882例),声带麻痹增加69%(n=1054-1777)。
    在COVID-19大流行爆发后,喉科手术的增加被确定为整体手术转向办公室设置。
    UNASSIGNED: The onset of the coronavirus disease 2019 (COVID-19) pandemic changed practice patterns throughout medicine. The purpose of this study is to evaluate changes in the volume and location setting of laryngology procedures after the onset of COVID-19.
    UNASSIGNED: Retrospective database cohort study.
    UNASSIGNED: Reg-ENT registry.
    UNASSIGNED: Retrospective review from 2017 to 2022 of patients who underwent a laryngology procedure identified by procedure code categorized by site of service code-\"ambulatory surgical\" versus \"office\" setting. Based on March 2020 as the cutoff point, the procedures were designated as pre-COVID versus COVID time period.
    UNASSIGNED: A total of 5989 patients underwent laryngology procedures. Forty-two percent more procedures were performed in the COVID period (n = 3780) versus pre-COVID (n = 2209). Pre-COVID, the procedure distribution between office and ambulatory surgical setting was 70% (n = 1546) compared with 30% (663). This shifted to 77% (n = 2920) and 23% (n = 860) during COVID, P = .9. The most common diagnoses associated with laryngology procedures during the study period were vocal fold paralysis 47% (n = 2831), dysphonia 33% (n = 1392), and laryngotracheal stenosis 14% (n = 838). These trends remained in both pre-COVID and COVID time periods. After the start of the pandemic, among patients undergoing laryngology procedures, there was a 93% increase (n = 284-549) in the diagnosis of laryngotracheal stenosis, 70% increase (n = 520-882 patients) in dysphonia and 69% increase (n = 1054-1777) in vocal fold paralysis.
    UNASSIGNED: An increase in laryngology procedures performed after the onset of the COVID-19 pandemic was identified with an overall procedural shift to the office-setting.
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  • 文章类型: Journal Article
    背景:ChatGPT是最流行的大型语言模型(LLM)之一,在各种标准化测试中表现出熟练程度,包括多项选择的医学委员会检查。然而,其在耳鼻咽喉头颈外科(OHNS)认证考试和开放式医疗委员会认证考试中的表现尚未报告。
    目的:我们旨在评估ChatGPT在OHNS板考试中的表现,并提出一种新颖的方法来评估AI模型在开放式医学板考试问题上的表现。
    方法:在2023年4月11日,加拿大皇家内科医生和外科医生学院的样本检查中采用了21个开放式问题来查询ChatGPT,有提示和无提示。一个新的模型,名为和谐,有效性,安全,能力(CVSC),是为了评估其性能而开发的。
    结果:在开放式问题评估中,ChatGPT在尝试中获得了通过分数(在3次试验中平均为75%),并在提示下表现出更高的准确性。该模型具有较高的一致性(92.06%)和令人满意的有效性。虽然在重新生成答案方面表现出相当大的一致性,它通常只提供部分正确的回答。值得注意的是,有关的特征,如幻觉和自我冲突的答案被观察。
    结论:ChatGPT在样本检查中取得了及格分数,并证明了通过加拿大皇家内科医生和外科医生学院的OHNS认证考试的潜力。由于它的幻觉,仍然存在一些担忧,这可能会给患者安全带来风险。需要进一步调整,以便为临床实施提供更安全,更准确的答案。
    BACKGROUND: ChatGPT is among the most popular large language models (LLMs), exhibiting proficiency in various standardized tests, including multiple-choice medical board examinations. However, its performance on otolaryngology-head and neck surgery (OHNS) certification examinations and open-ended medical board certification examinations has not been reported.
    OBJECTIVE: We aimed to evaluate the performance of ChatGPT on OHNS board examinations and propose a novel method to assess an AI model\'s performance on open-ended medical board examination questions.
    METHODS: Twenty-one open-ended questions were adopted from the Royal College of Physicians and Surgeons of Canada\'s sample examination to query ChatGPT on April 11, 2023, with and without prompts. A new model, named Concordance, Validity, Safety, Competency (CVSC), was developed to evaluate its performance.
    RESULTS: In an open-ended question assessment, ChatGPT achieved a passing mark (an average of 75% across 3 trials) in the attempts and demonstrated higher accuracy with prompts. The model demonstrated high concordance (92.06%) and satisfactory validity. While demonstrating considerable consistency in regenerating answers, it often provided only partially correct responses. Notably, concerning features such as hallucinations and self-conflicting answers were observed.
    CONCLUSIONS: ChatGPT achieved a passing score in the sample examination and demonstrated the potential to pass the OHNS certification examination of the Royal College of Physicians and Surgeons of Canada. Some concerns remain due to its hallucinations, which could pose risks to patient safety. Further adjustments are necessary to yield safer and more accurate answers for clinical implementation.
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  • 文章类型: Journal Article
    目前的文献对声门鳞状细胞癌(SCC)经口激光显微手术(TLM)后阳性切缘(PM)的管理提供了有限的指导。探索通过初始观察和再次切除治疗PMs的长期数据有限。我们的目标是确定TLM治疗声门SCC后PM患者的最佳治疗方法。
    2007年至2018年在我们机构前瞻性收集了TLM治疗后患有PMs的声门SCC患者的临床信息。我们在初始TLM期间使用喉模板,其中概述了切除区域以供将来参考。将数据与单变量分析进行比较,并使用Kaplan-Meier方法生成生存图。
    总共29例PMs患者接受了再次切除治疗(19例患者),密切观察(6例),或单独辅助放射(4例)。重新切除的患者在初始边缘病理上有SCC或严重的异型增生,23%的早期疾病复发(T1-T2)。5例(83%)接受密切观察的患者根据临床怀疑复发(最终病理证实)需要再次切除。与再切除患者有显著差异(p<.05)。因此,停止密切观察作为PMs的管理。四名患者(21%)在再切除标本上没有残留恶性肿瘤。深边缘仅占所有PM的17%。所有PM患者5年的疾病特异性生存率为82.4%(SE9.6%,CI53.4%-91.6%)。
    我们用TLM治疗早期声门SCC的长期经验支持再次切除作为PMs病例的适当管理。
    4.
    UNASSIGNED: The current literature provides limited guidance on the management of positive margins (PMs) following transoral laser microsurgery (TLM) for glottic squamous cell carcinoma (SCC). Long-term data exploring the treatment of PMs with both initial observation and re-resection are limited. Our objective was to determine the optimal treatment for PM patients following TLM for glottic SCC.
    UNASSIGNED: Clinical information on glottic SCC patients with PMs following treatment with TLM was prospectively collected at our institution from 2007 to 2018. We use a laryngeal template during the initial TLM where the area of resection is outlined for future reference. Data were compared with univariate analysis and survival plots were generated using the Kaplan-Meier method.
    UNASSIGNED: A total of 29 patients with PMs were treated with either re-resection (19 patients), close observation (6 patients), or adjuvant radiation alone (4 patients). Re-resection patients had SCC or severe dysplasia on initial margin pathology and 23% with early-stage disease had recurrence (T1-T2). Five (83%) patients who underwent close observation required re-resection based on clinical suspicion of recurrence (confirmed on final pathology), which was significantly different from the re-resection patients (p < .05). Close observation was therefore discontinued as a management of PMs. Four patients (21%) had no residual malignancy on re-resection specimens. Deep margins only accounted for 17% of all PMs. Disease-specific survival for all PM patients at 5 years was 82.4% (SE 9.6%, CI 53.4%-91.6%).
    UNASSIGNED: Our long-term experience with treating early-stage glottic SCC with TLM supports re-resection as an appropriate management for cases of PMs.
    UNASSIGNED: 4.
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  • 文章类型: Journal Article
    目的:通过口咽部pH监测和胃蛋白酶唾液测量,探讨阻塞性睡眠呼吸暂停(OSA)与咽喉反流(LPR)之间的关系。
    方法:前瞻性非对照研究。
    方法:有睡眠障碍和反流症状的患者接受多导睡眠监测,24小时口咽pH监测和唾液胃蛋白酶收集。根据口咽pH监测和胃蛋白酶测量,对OSA患者的LPR患病率进行了调查。pH监测结果之间进行了相关性分析,胃蛋白酶唾液水平,反流症状评分-12(RSS-12),反流体征评估(RSA),呼吸暂停-呼吸不足指数(AHI),Epworth嗜睡量表,Pichot和唤醒发现。
    结果:37名患者完成了评估。在口咽pH监测和胃蛋白酶试验中,34/37(92%)和29/34(85%)患者检测到LPR,分别。在30例患者中检测到OSA(81%)。其中,28/30(93%)例检出LPR。咽部反流事件主要发生在OSA患者的夜间/仰卧位。Ryan评分和pH<6.5时仰卧反流时间均与BMI和RSA分和总分显著相关(p<0.02)。舌基肥大评分与微觉醒次数呈正相关(p=0.027);pH<6.5的仰卧百分比(p=0.030);早晨(p=0.030)和睡前胃蛋白酶唾液测量值(p=0.037)。睡前胃蛋白酶唾液水平与Ryan评分(p=0.047)、AHI(p=0.017)和睡眠饱和<90%时间(p=0.040)显著相关。早晨胃蛋白酶的唾液水平与最短的矛盾睡眠阶段有关(p=0.013)。
    结论:OSA患者在口咽部pH监测和高胃蛋白酶唾液测量中可能有较高的咽部反流事件发生率。口咽pH监测应有助于OSA患者的反流与睡眠结果之间的相关性。需要未来的大型队列对照研究来确定OSA和健康个体中LPR的患病率。
    OBJECTIVE: To investigate the association between obstructive sleep apnea (OSA) and laryngopharyngeal reflux (LPR) through oropharyngeal pH-monitoring and pepsin saliva measurements.
    METHODS: Prospective uncontrolled study.
    METHODS: Patients with sleep disturbances and reflux symptoms underwent polysomnography, 24-h oropharyngeal pH-monitoring and saliva pepsin collections. The prevalence of LPR was investigated in OSA patients according to oropharyngeal pH-monitoring and pepsin measurements. A correlation analysis was performed between pH-monitoring findings, pepsin saliva levels, reflux symptom score-12 (RSS-12), reflux sign assessment (RSA), Apnea-Hypopnea Index (AHI), Epworth Sleepiness Scale, Pichot and arousal findings.
    RESULTS: Thirty-seven patients completed the evaluations. LPR was detected in 34/37 (92%) and 29/34 (85%) patients at the oropharyngeal-pH monitoring and pepsin test, respectively. OSA was detected in 30 patients (81%). Among them, LPR was detected in 28/30 (93%) cases. Pharyngeal reflux events mainly occurred nighttime/supine in OSA patients. Both Ryan score and supine reflux time at pH < 6.5 were significantly associated with BMI and the RSA sub- and total scores (p < 0.02). Tongue-base hypertrophy score was positively associated with the number of micro-arousals (p = 0.027); the supine percent of pH < 6.5 (p = 0.030); morning (p = 0.030) and bedtime pepsin saliva measurements (p = 0.037). The bedtime pepsin saliva level was significantly associated with Ryan Score (p = 0.047); AHI (p = 0.017) and the sleep saturation < 90% time (p = 0.040). The saliva level of the morning pepsin was associated with a shortest paradoxical sleep phase (p = 0.013).
    CONCLUSIONS: OSA patients may have high prevalence of pharyngeal reflux events at the oropharyngeal pH-monitoring and high pepsin saliva measurements. Oropharyngeal pH-monitoring should be useful for the correlation between reflux and sleep findings in OSA patients. Future large cohort controlled studies are needed to determine the prevalence of LPR in OSA and healthy individuals.
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  • 文章类型: Journal Article
    目的:研究经口CO2激光显微手术(TLM)患者术后嗓音质量随年龄的变化。
    方法:前瞻性招募接受I至VI型TLM和术后言语治疗的患者。语音质量是预先评估的,1-,3-6-和12个月的治疗后语音障碍指数(VHI),发音困难,粗糙度,呼吸,虚弱,应变(GRBAS),最大发声时间(MPT),F0,F0标准偏差(STD),百分比抖动,微光百分比,噪声谐波比(NHR),声带振动评估和语音流畅性。考虑患者年龄,分析了嗓音结果的演变(<60vs.≥60岁)。
    结果:75名患者完成了评估。34例和41例患者<60岁或≥60岁,分别。主客观语音参数(VHI,G,R,B),在<60岁的个体中,从TLM后1到6个月,抖动和流畅度显着改善。在≥60yo组中,TLM后12个月的语音参数有所改善,但VHI在TLM后3个月有所改善。年龄和12个月NHR之间存在正相关,G和A参数。
    结论:术后语音质量参数的演变可能因患者年龄而异。术前VHI可预测12个月的主观和客观语音结果。
    OBJECTIVE: To study the post-operative evolution of voice quality of patients treated by transoral CO2 laser microsurgery (TLM) according to the age.
    METHODS: Patients treated by type I to VI TLM and post-operative speech therapy were prospectively recruited from our hospital. The voice quality was assessed pre-, 1-, 3- 6- and 12-month posttreatment with voice handicap index (VHI), dysphonia, roughness, breathiness, asthenia, strain (GRBAS), maximal phonation time (MPT), F0, F0 standard deviation (STD), percent jitter, percent shimmer, noise-to-harmonic ratio (NHR), vocal fold vibration assessment and speech fluency. Evolution of voice outcomes was analyzed considering age of patients (< 60 vs. ≥ 60 years).
    RESULTS: Seventy-five patients completed the evaluations. Thirty-four and forty-one patients were < 60 or ≥ 60 yo, respectively. Subjective and objective voice parameters (VHI, G, R, B), jitter and fluency significantly improved from 1- to 6-month post-TLM in < 60 yo individuals. The voice parameters improved 12-month post-TLM in the ≥ 60 yo group at the exception of VHI that improved 3-month post-TLM. There were positive associations between age and 12-month NHR, G and A parameters.
    CONCLUSIONS: The post-operative evolution of voice quality parameters may vary between patients according to the age. Preoperative VHI is predictive of 12-month subjective and objective voice outcomes.
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  • 文章类型: Journal Article
    背景和目的:研究禁闭对咽喉反流(LPR)患者饮食依从性和应激水平的影响。材料和方法:在下咽食管阻抗-pH监测中LPR诊断阳性的患者,从3个月的高蛋白治疗前到锁定期,低脂肪,碱性,植物性饮食,随着行为的改变,以及泮托拉唑(20MG/d)和藻酸盐(Gaviscon3/d)的联合。使用以下患者报告的结果问卷和发现工具:反流症状评分-12(RSS-12)和反流体征评估(RSA)。在后处理时间,邀请患者使用预定义的食物和饮料网格以及感知压力量表(PSS)评估封锁对饮食依从性和压力管理的影响,分别。结果:32例患者完成评估。RSS-12和RSA从基线到治疗后3个月显著改善。大多数患者在封锁结束时经历了轻度到重度的压力水平。由于封锁,11名患者(34%)的压力水平大幅增加,而11例患者(44%)没有改变。在11例(34%)中,患者报告说,由于封锁期,抗反流饮食的依从性比最初推测的要好,而44%(N=14)的人报告说封锁不会影响对饮食的依从性。PSS和RSS-12在大流行结束时显著相关(rs=0.681;p<0.001)。压力水平的增加与缺乏饮食依从性呈正相关(rs=0.367;p=0.039)。结论:在封锁期间,1/3的LPR患者的饮食习惯得到改善,44%的患者没有改变.三分之一的患者的压力水平增加,这与症状评分的增加有关。
    Background and Objective: To examine the effects of the lockdown on diet adherence and stress levels in patients with laryngopharyngeal reflux (LPR). Materials and Methods: Patients with a positive LPR diagnosis at the hypopharyngeal-esophageal impedance-pH monitoring were treated from a pre- to lockdown period with a 3-month high-protein, low-fat, alkaline, plant-based diet, with behavioral changes, and an association of pantoprazole (20 MG/d) and alginate (Gaviscon 3/d). The following patient-reported outcomes questionnaire and findings instrument were used: Reflux Symptom Score-12 (RSS-12) and Reflux Sign Assessment (RSA). At the posttreatment time, patients were invited to evaluate the impact of lockdown on diet adherence and stress management with a predefined grid of foods and beverages and the perceived stress scale (PSS), respectively. Results: Thirty-two patients completed the evaluations. RSS-12 and RSA significantly improved from baseline to 3-month posttreatment. Most patients experienced mild-to-severe stress levels at the end of the lockdown. The level of stress substantially increased in 11 patients (34%) due to the lockdown, while it did not change in 11 patients (44%). In 11 cases (34%), patients reported that the adherence to the anti-reflux diet was better than initially presumed thanks to the lockdown period, while 44% (N = 14) reported that the lockdown did not impact the adherence to a diet. PSS and RSS-12 were significantly correlated at the end of the pandemic (rs = 0.681; p < 0.001). The increase in stress level was positively associated with the lack of adherence to diet (rs = 0.367; p = 0.039). Conclusions: During the lockdown, the diet habits of LPR patients were improved in one-third and unchanged in 44% of cases. The stress level was increased in one-third of patients, which was associated with an increase in symptom scores.
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