■颌骨成釉细胞瘤的手术治疗由于其变异的复发率不同,仍然存在争议,肿瘤的局部侵袭行为,以及外科医生对邻近健康组织的切除程度缺乏共识。
■确定成釉细胞瘤的复发率及其与切除边缘的关系。
■这是一项回顾性队列研究,对接受颌骨手术切除作为成釉细胞瘤主要治疗方式的患者的医疗记录。对26年的临床数据进行年龄分析,性别,病变部位,尺寸,射线照相外观,组织病理学亚型,以及治疗后复发的发生率。计算描述性和双变量统计量。
■研究中纳入了234例典型(实性/多囊性)成釉细胞瘤病例的回顾性审核。患者年龄20~66岁,平均年龄33.4±9.6岁,男女比例为1.2:1(P=0.52)。卵泡和丛状类型占组织病理学变异的大多数(89.8%;P=0.000)。总的来说,6.8%的病例在初次手术后复发。切除边缘为1.0或1.5cm比2.0cm的复发率高(P=0.001)。切除边缘为2.5cm,未见复发病例。
■在我们的一系列病例中发现了6.8%的低复发率。建议在邻近的健康组织中切除2.5cm宽的切缘。
UNASSIGNED: The surgical treatment of ameloblastoma of the
jaws remains contentious due to the variable recurrence rate amongst its variants, the tumor\'s local invasive behavior, and the lack of consensus among surgeons concerning the extent of resection in the contiguous healthy tissues.
UNASSIGNED: To determine the recurrence rate of ameloblastoma and its association with the resection margins.
UNASSIGNED: This is a retrospective cohort study of the medical records of patients who underwent surgical resection of the
jaws as the primary modality of treatment for ameloblastoma. Clinical data over the 26 years were analyzed for age, gender, site of the lesion, size, radiographic appearance, histopathological sub-type, and the incidence of recurrence post-treatment. Descriptive and bivariate statistics were computed.
UNASSIGNED: A retrospective audit of 234 cases was included in the study that was typical (solid/multicystic) ameloblastoma. The age of patients ranged from 20 to 66 years with a mean age of 33.4 ± 9.6 years, and a male-to-female ratio of 1.2: 1 (P = 0.52). The follicular and plexiform types accounted for the majority of histopathological variants (89.8%; P = 0.000). Overall, 6.8% of cases relapsed after the initial primary surgery. The rate of recurrence was high with a resection margin of 1.0 or 1.5 cm than 2.0 cm (P = 0.001). No case of recurrence was seen with a resection margin of 2.5 cm margin.
UNASSIGNED: A low recurrence rate of 6.8% was noted in our series of cases. A wide 2.5 cm resection margin is recommended in the adjacent healthy tissues.