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Abstract：
BACKGROUND: This study aimed to investigate the clinicopathological features of metastases in the oral and maxillofacial regions.
METHODS: In this retrospective study, biopsy records were obtained from referral centers for oral and maxillofacial diagnosis in Brazil, Guatemala, Mexico, and South Africa.
RESULTS: A total of 120 cases were evaluated. Of these, 53.78% affected female patients, with a mean age of 57.64 years. Intraosseous lesions were more frequent, particularly in the posterior region of the mandible (49.58%). Clinically, most cases presented with symptomatic swelling, with an average evolution time of 25 months. The clinical diagnostic hypothesis in most instances was that of a malignant lesion. Breast cancer was the most common primary tumor location in females, while lung origin was most common in males. In most cases, the primary cancer was an adenocarcinoma (44.73%). The follow-up period was available for 29 cases, and out of these, 20 had died due to the disease.
CONCLUSIONS: Although this is a rare condition, clinicians should be aware that any oral lesions have the possibility of being metastatic, particularly in individuals with a previous history of cancer. The findings from this study could assist clinicians in prompt diagnosing these lesions and subsequent conducting oncologic assessments and treatment.
METHODS: In this retrospective study, biopsy records were obtained from referral centers for oral and maxillofacial diagnosis in Brazil, Guatemala, Mexico, and South Africa.
RESULTS: A total of 120 cases were evaluated. Of these, 53.78% affected female patients, with a mean age of 57.64 years. Intraosseous lesions were more frequent, particularly in the posterior region of the mandible (49.58%). Clinically, most cases presented with symptomatic swelling, with an average evolution time of 25 months. The clinical diagnostic hypothesis in most instances was that of a malignant lesion. Breast cancer was the most common primary tumor location in females, while lung origin was most common in males. In most cases, the primary cancer was an adenocarcinoma (44.73%). The follow-up period was available for 29 cases, and out of these, 20 had died due to the disease.
CONCLUSIONS: Although this is a rare condition, clinicians should be aware that any oral lesions have the possibility of being metastatic, particularly in individuals with a previous history of cancer. The findings from this study could assist clinicians in prompt diagnosing these lesions and subsequent conducting oncologic assessments and treatment.
摘要：
背景：本研究旨在探讨口腔颌面部转移瘤的临床病理特征。
方法：在这项回顾性研究中，活检记录来自巴西口腔颌面诊断转诊中心，危地马拉,墨西哥,和南非。
结果：共评估120例。其中,53.78%受影响的女性患者，平均年龄为57.64岁。骨内病变更常见，特别是在下颌骨的后部（49.58％）。临床上,大多数病例表现为症状性肿胀，平均进化时间为25个月。在大多数情况下，临床诊断假设是恶性病变。乳腺癌是女性最常见的原发肿瘤,而肺起源在男性中最常见。在大多数情况下,原发癌为腺癌(44.73%).随访期29例，在这些之外，20人因疾病死亡。
结论：虽然这是一种罕见的情况，临床医生应该意识到任何口腔病变都有转移的可能性，特别是在有癌症病史的个体中。这项研究的发现可以帮助临床医生及时诊断这些病变并随后进行肿瘤学评估和治疗。
方法：在这项回顾性研究中，活检记录来自巴西口腔颌面诊断转诊中心，危地马拉,墨西哥,和南非。
结果：共评估120例。其中,53.78%受影响的女性患者，平均年龄为57.64岁。骨内病变更常见，特别是在下颌骨的后部（49.58％）。临床上,大多数病例表现为症状性肿胀，平均进化时间为25个月。在大多数情况下，临床诊断假设是恶性病变。乳腺癌是女性最常见的原发肿瘤,而肺起源在男性中最常见。在大多数情况下,原发癌为腺癌(44.73%).随访期29例，在这些之外，20人因疾病死亡。
结论：虽然这是一种罕见的情况，临床医生应该意识到任何口腔病变都有转移的可能性，特别是在有癌症病史的个体中。这项研究的发现可以帮助临床医生及时诊断这些病变并随后进行肿瘤学评估和治疗。
