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Abstract：
Aneurysmal bone cyst is a rare osteolytic lesion of uncertain etiology, commonly observed in the lower limbs, with only 1-2% of reports in gnathic bones. We present the case of a 27-year-old male patient referred to the oral and maxillofacial surgery and traumatology service due to complaints of paresthesia in the mental region and increased mandibular volume. Physical examination revealed midline shift and hard consistency. Imaging examinations demonstrated a radiolucent/hypodense lesion with disruption of the mandibular cortices. The histopathological examination of incisional biopsy material led to the diagnosis of a central giant cell lesion. The patient underwent surgical resection, and the histopathological analysis of the specimen revealed a predominantly solid lesion, characterized by blood-filled spaces of varying size, not covered by epithelium or endothelium, with the presence of spindle cells, multinucleated giant cells, and basophilic osteoid material, concluding the diagnosis of mixed-type aneurysmal bone cyst. Despite being uncommon, aneurysmal bone cysts should be considered in the differential diagnosis of volumetric increase in the gnathic bones of young patients.
摘要：
动脉瘤性骨囊肿是一种病因不明的罕见溶骨性病变，通常在下肢观察到，只有1-2%的报告在颌骨。我们介绍了一名27岁的男性患者的病例，该患者因精神区域感觉异常和下颌体积增加而转诊口腔颌面外科和创伤学服务。体格检查显示中线移位和硬一致性。影像学检查显示下颌皮质破裂，有射线可透/低密度病变。切开活检材料的组织病理学检查导致中央巨细胞病变的诊断。病人接受了手术切除,标本的组织病理学分析显示主要为实体病变，以不同大小的充满血液的空间为特征，不被上皮或内皮覆盖，随着梭形细胞的存在，多核巨细胞,和嗜碱性骨样物质，结论诊断为混合型动脉瘤样骨囊肿。尽管不常见，在年轻患者颌骨体积增加的鉴别诊断中，应考虑动脉瘤性骨囊肿。
