本研究的目的是探讨颅内恶性黑色素瘤的临床诊断和治疗。为此,临床表现,标志,脑脊液(CSF)内容物,意象学,病理特征,分析中国人民解放军总医院7例颅内恶性黑色素瘤的治疗及预后,中国)从1996年到2013年。所有黑色素瘤病例均经组织病理学证实,脑脊液细胞病理学检查显示原发性恶性黑色素瘤5例,继发性恶性黑色素瘤2例。在患者中,4在皮肤中呈现>1色素痣,1例皮肤黑色素瘤。颅内恶性黑色素瘤主要影响中年男性。CSF细胞病理学和影像学(特别是增强磁共振),是诊断疾病的重要工具。特别是,当患者出现皮肤色素痣和大脑异常病变时,应考虑颅内恶性黑色素瘤的诊断。
The aim of the present study was to investigate the clinical diagnosis and treatment of intracranial malignant melanoma. For this purpose, the clinical manifestation, signs, cerebrospinal fluid (CSF) contents,
imageology, pathological features, treatment and prognosis of 7 cases of intracranial malignant melanoma were analyzed in The Chinese PLA General Hospital (Beijing, China) from 1996 to 2013. All the melanoma cases were confirmed by histopathology, and CSF cytopathology demonstrated that there were 5 cases of primary malignant melanoma and 2 cases of secondary malignant melanoma. Among the patients, 4 presented with >1 pigmented nevus in the skin, and 1 presented with skin melanoma. Intracranial malignant melanoma mostly affects middle-aged males. CSF cytopathology and
imageology (particularly enhanced magnetic resonance), are important tools in the diagnosis of the disease. Particularly, when a patient presents with a pigmented nevus in the skin and an abnormal lesion in the brain, a diagnosis of intracranial malignant melanoma should be considered.