PDF(Pubmed)
Abstract：
UNASSIGNED: Extra-adrenal myelolipomas (EAMs) are rare benign tumors composed of both mature adipose and hematopoietic tissues with unclear etiology. There have been only sporadic case reports about the clinical characteristics and management of EAMs. Here we present our experience and practice in the clinical diagnosis and treatment of 11 consecutive patients with EAMs.
UNASSIGNED: We retrospectively reviewed 11 consecutive patients, who received surgeries in our department and were confirmed as having EAMs by postoperative histopathology from April 2016 to December 2021. Clinical information and follow-up data of all patients were collected and analyzed afterwards.
UNASSIGNED: Of the 11 EAM patients (7 male and 4 female) with a mean age of 47.6 years, 3 were asymptomatic and 8 were symptomatic with a mean symptom duration of 6.07 months. EAMs were found in the thoracic spine in 4 cases, paravertebral mediastinal regions in 3 cases, ilium in 2 cases, humerus in 1 case, and rib in 1 case. All patients were initially misdiagnosed as other tumors by radiologists. All 11 patients received gross total excision or curettage with a mean intraoperative blood loss of 781.82 ± 1143.3 ml and a mean operation duration of 180.91 ± 98.41 min. Patients\' Frankel scores and Karnofsky Performance Status score were improved or at least preserved postoperatively. No significant complications occurred postoperatively. All the 11 patients survived, and no local recurrence or distant metastasis occurred during the mean follow-up period of 42.0 months.
UNASSIGNED: The surgical outcome and prognosis of EAMs are excellent and surgery can serve as the method of radical treatment.
UNASSIGNED: We retrospectively reviewed 11 consecutive patients, who received surgeries in our department and were confirmed as having EAMs by postoperative histopathology from April 2016 to December 2021. Clinical information and follow-up data of all patients were collected and analyzed afterwards.
UNASSIGNED: Of the 11 EAM patients (7 male and 4 female) with a mean age of 47.6 years, 3 were asymptomatic and 8 were symptomatic with a mean symptom duration of 6.07 months. EAMs were found in the thoracic spine in 4 cases, paravertebral mediastinal regions in 3 cases, ilium in 2 cases, humerus in 1 case, and rib in 1 case. All patients were initially misdiagnosed as other tumors by radiologists. All 11 patients received gross total excision or curettage with a mean intraoperative blood loss of 781.82 ± 1143.3 ml and a mean operation duration of 180.91 ± 98.41 min. Patients\' Frankel scores and Karnofsky Performance Status score were improved or at least preserved postoperatively. No significant complications occurred postoperatively. All the 11 patients survived, and no local recurrence or distant metastasis occurred during the mean follow-up period of 42.0 months.
UNASSIGNED: The surgical outcome and prognosis of EAMs are excellent and surgery can serve as the method of radical treatment.
摘要：
■肾上腺外骨髓脂肪瘤（EAMs）是罕见的良性肿瘤，由成熟的脂肪和造血组织组成，病因不明。关于EAM的临床特征和管理只有零星的病例报告。在这里，我们介绍了我们在11例连续EAM患者的临床诊断和治疗中的经验和实践。
■我们回顾性回顾了11例连续患者，从2016年4月至2021年12月,患者在我们部门接受了手术,并通过术后组织病理学证实患有EAMs.收集所有患者的临床资料及随访资料并进行分析。
■在11例EAM患者（7例男性和4例女性）中，平均年龄为47.6岁，3例无症状，8例有症状，平均症状持续时间为6.07个月。4例在胸椎发现EAM，椎旁纵隔3例,髂骨2例，一例肱骨,和肋骨在1个案例中。所有患者最初被放射科医生误诊为其他肿瘤。所有11例患者均接受了大体全切除或刮宫术，术中平均失血量为781.82±1143.3ml，平均手术时间为180.91±98.41min。患者的Frankel评分和Karnofsky表现状态评分在术后得到改善或至少得到保留。术后无明显并发症发生。11名患者全部存活,平均随访42.0个月,无局部复发或远处转移。
■EAM的手术效果和预后良好，手术可作为根治性治疗的方法。
■我们回顾性回顾了11例连续患者，从2016年4月至2021年12月,患者在我们部门接受了手术,并通过术后组织病理学证实患有EAMs.收集所有患者的临床资料及随访资料并进行分析。
■在11例EAM患者（7例男性和4例女性）中，平均年龄为47.6岁，3例无症状，8例有症状，平均症状持续时间为6.07个月。4例在胸椎发现EAM，椎旁纵隔3例,髂骨2例，一例肱骨,和肋骨在1个案例中。所有患者最初被放射科医生误诊为其他肿瘤。所有11例患者均接受了大体全切除或刮宫术，术中平均失血量为781.82±1143.3ml，平均手术时间为180.91±98.41min。患者的Frankel评分和Karnofsky表现状态评分在术后得到改善或至少得到保留。术后无明显并发症发生。11名患者全部存活,平均随访42.0个月,无局部复发或远处转移。
■EAM的手术效果和预后良好，手术可作为根治性治疗的方法。
