%0 Journal Article
%T Cardiac imageology changes in patients with mild obstructive sleep apnea without cardiovascular disease.
%A Hong Z
%A Ou Q
%A Cheng Y
%A Xu Y
%A Fei H
%A Liu H
%J Sleep Breath
%V 0
%N 0
%D Jun 2021 29
%M 34185231
%F 2.655
%R 10.1007/s11325-021-02421-0
%X <B>OBJECTIVE: </B>This study aims to assess changes in cardiac imageology of patients with mild obstructive sleep apnea (OSA) without cardiovascular disease.<BR><B>METHODS: </B>All enrolled participants underwent polysomnography (PSG). Some participants underwent transthoracic echocardiography, speckle tracking echocardiography, and cardiac-enhanced magnetic resonance imaging (MRI) if they were willing. They were divided into three groups according to PSG results: non-OSA, mild OSA, and moderate-to-severe OSA. Imageology parameters were compared, and the relationship between OSA severity and imageology indices was analyzed by correlation analysis and multiple linear regression.<BR><B>RESULTS: </B>Of the 352 enrolled participants, 274 participants with OSA had an apnea-hypopnea index (AHI) of ≥ 5 (86 mild OSA and 188 moderate-to-severe OSA cases), and 78 participants with non-OSA had an AHI of < 5. Transthoracic echocardiography showed that E/A and E'/A' values were lower in the mild OSA group than in the non-OSA group (1.12 ± 0.37 vs 1.27 ± 0.45 and 0.83 ± 0.33 vs 0.99 ± 0.42, respectively, p < 0.05). The aorta and ascending aorta widths were smaller in the mild OSA group than in the moderate-and-severe OSA groups (27.36 ± 2.87 mm vs 28.87 ± 2.95 mm and 30.27 ± 3.79 mm vs 31.63 ± 3.74 mm, respectively, p < 0.05). A regression analysis showed that cardiac function changes in patients with OSA may be related to age, obesity, and OSA severity.<BR><B>CONCLUSIONS: </B>Patients with mild OSA without cardiovascular disease displayed changes in cardiac structure and function on transthoracic echocardiography.