{Reference Type}: Journal Article
{Title}: Surgical management and outcome of Extra-adrenal myelolipomas at unusual locations: A report of 11 cases in a single center.
{Author}: Cao J;Huang X;Cui N;Wang X;You C;Ni X;Gao X;Wang J;Liu T;
{Journal}: J Bone Oncol
{Volume}: 35
{Issue}: 0
{Year}: Aug 2022
暂无{DOI}: 10.1016/j.jbo.2022.100438
{Abstract}: UNASSIGNED: Extra-adrenal myelolipomas (EAMs) are rare benign tumors composed of both mature adipose and hematopoietic tissues with unclear etiology. There have been only sporadic case reports about the clinical characteristics and management of EAMs. Here we present our experience and practice in the clinical diagnosis and treatment of 11 consecutive patients with EAMs.
UNASSIGNED: We retrospectively reviewed 11 consecutive patients, who received surgeries in our department and were confirmed as having EAMs by postoperative histopathology from April 2016 to December 2021. Clinical information and follow-up data of all patients were collected and analyzed afterwards.
UNASSIGNED: Of the 11 EAM patients (7 male and 4 female) with a mean age of 47.6 years, 3 were asymptomatic and 8 were symptomatic with a mean symptom duration of 6.07 months. EAMs were found in the thoracic spine in 4 cases, paravertebral mediastinal regions in 3 cases, ilium in 2 cases, humerus in 1 case, and rib in 1 case. All patients were initially misdiagnosed as other tumors by radiologists. All 11 patients received gross total excision or curettage with a mean intraoperative blood loss of 781.82 ± 1143.3 ml and a mean operation duration of 180.91 ± 98.41 min. Patients' Frankel scores and Karnofsky Performance Status score were improved or at least preserved postoperatively. No significant complications occurred postoperatively. All the 11 patients survived, and no local recurrence or distant metastasis occurred during the mean follow-up period of 42.0 months.
UNASSIGNED: The surgical outcome and prognosis of EAMs are excellent and surgery can serve as the method of radical treatment.