Fracture

骨折
  • 文章类型: Journal Article
    患者的主要原因之一,尤其是老年人,被带到骨科急诊室的是桡骨末端的骨折。在这项研究中,将桡骨远端骨折的新牵引方法与手动复位进行了比较。
    在这项临床试验中使用了人口普查方法,以研究2021年转诊到HamedanBesat医院的45名患者(46只手)。患者被随机分为两组。在A组中实施了手动降低(由助手和医生进行压力和牵引)方法,在B组中进行了新的牵引程序(通过硬件或设备进行压力和牵引)。在手术后的第1周和第6周,对两组的减少的影像学结果进行了调查和比较。
    在术后第六周的新和手动组中观察到以下结果:平均掌侧倾斜:4.19±3.79和4.08±3.88(p=0.926),径向角度:2.18±1.27和2.21±1.35(p=0.934),径向缩短:10.52±0.65和10.56±0.68(p=0.828),径向倾角:22.52±2.46和22.71±2.01(p=0.787),背角:-5.89±0.33和5.22±-1.91(p=1.00),尺骨方差:1.66±0.90和1.67±0.81(p=0.958),平均疼痛评分:2.40±0.68和2.47±0.73(p=0.737)。
    桡骨远端骨折患者的新的硬件复位程序在影像学改变和骨折部位的疼痛评分方面显示出与传统的基于助手和医生的压力和牵引方法相同的效果。
    UNASSIGNED: One of the leading reasons that patients, particularly older persons, are brought to the orthopedic emergency room is a fracture at the end of the radius. In this study, a new traction method for distal radius fractures was compared with manual reduction.
    UNASSIGNED: The census method was used in this clinical trial to study 45 patients (46 hands) who were referred to Hamedan Besat Hospital in 2021. Patients were randomly assigned to two groups. The manual reduction (pressure and traction by an assistant and a doctor) method was implemented in Group A, and the new traction procedure (pressure and traction by hardware or a device) was performed in Group B. The radiographic results of reduction in both groups were investigated and compared immediately and in the first and 6 weeks after surgery.
    UNASSIGNED: The following results were observed in the new and manual groups in the sixth week after surgery: average volar tilt: 4.19 ± 3.79 and 4.08 ± 3.88 (p = 0.926), radial angulation: 2.18 ± 1.27 and 2.21 ± 1.35 (p = 0.934), radial shortening: 10.52 ± 0.65 and 10.56 ± 0.68 (p = 0.828), radial inclination: 22.52 ± 2.46 and 22.71 ± 2.01 (p = 0.787), dorsal angulation: -5.89 ± 0.33 and 5.22 ± -1.91 (p = 1.00), ulnar variance: 1.66 ± 0.90 and 1.67 ± 0.81 (p = 0.958), and average pain score: 2.40 ± 0.68 and 2.47 ± 0.73 (p = 0.737).
    UNASSIGNED: The new reduction procedure with hardware in patients with distal radius fractures showed the same effect as the traditional method based on pressure and traction by the assistant and doctor in terms of radiographic changes and pain score of the fracture site.
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  • 文章类型: Case Reports
    小儿创伤中的骨盆骨折占总住院人数的0.5-1%,而髋臼骨折的发生率为每100,000名儿童中1例;其发生率较低是由于其独特的特点.这个年龄段的标准化管理是不可能的。保守治疗已被普遍使用,但手术矫正已获得普及。这项研究的目的是报告作者使用有限的髂腹股沟入路治疗两名幼儿不稳定骨盆骨折的经验。
    案例研究描述。
    这里,我们描述了两名患者的治疗:一名男性患者被车辆撞击(年龄为1岁零7个月)和一名女性患者被汽车逐出(年龄为2岁零1个月)。在改良的Torode和Zieg分类中,他们维持了不稳定的IV型骨折。使用有限的髂腹股沟入路进行手术治疗,并使用3.5-mm重建板实现稳定。无医源性神经损伤或感染。该女性患者在手术后2个月出现左髋关节脱位,不幸失去随访。男性患者实现放射学骨愈合,没有差异,在平均18个月的随访期间,没有减轻或疼痛的证据。
    儿童骨盆骨折是罕见的。根据断裂模式,手术稳定可能是必要的,以防止短期的重大并发症,中等,或长期。有限的髂腹股沟入路被证明是治疗年龄<3岁儿童不稳定骨盆骨折的可行替代方法,血液最少,手术时间短。允许更多的解剖和稳定的减少。
    UNASSIGNED: Pelvic fractures in pediatric trauma account for 0.5-1 % of total hospital admissions, whereas acetabular fracture occurs at a rate of one case per 100,000 children; the low presentation rate is due to its unique characteristics. Standardized management for this age group is impossible. Conservative treatment has been commonly used but surgical correction has gained popularity. The purpose of this study was to report the authors\' experience using a limited ilioinguinal approach for unstable pelvic fracture in two toddlers.
    UNASSIGNED: Description of case studies.
    UNASSIGNED: Herein, we describe the treatment of two patients: a male patient struck by a vehicle (aged 1 year and 7 months) and a female patient ejected from a motor vehicle (aged 2 years and 1 month). They sustained an unstable type IV fracture in the modified Torode and Zieg classification. Surgical treatment was performed using a limited ilioinguinal approach, and stabilization was achieved using 3.5-mm reconstruction plate. There were no iatrogenic nerve injuries or infection. The female patient had left hip dislocation 2 months post-surgery and was unfortunately lost to follow-up. The male patient achieved radiological bone union without discrepancy, with no loss of reduction or evidence of pain during the mean follow-up period of 18 months.
    UNASSIGNED: Pelvic fracture in children is rare. Based on fracture patterns, surgical stabilization may be necessary to prevent major complications in the short, medium, or long term. The limited ilioinguinal approach was proven to be a viable alternative for managing unstable pelvic fracture in children aged <3 years with minimal blood lo and shorter operative time, allowing more anatomical and stable reduction.
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  • 文章类型: Case Reports
    道路交通事故后,成年人经常遇到多处骨折。一名32岁男性右下肢多处骨折,包括股骨干骨折,胫骨和腓骨远端第三骨折,还有跟骨骨折.患者提供了指示道路交通事故的历史。对两个髋关节进行了X射线检查,两个膝关节,还有踝关节.治疗包括股骨切开复位和内固定(ORIF)带锁钉,胫骨,和腓骨,与ORIF一起使用螺钉外固定(SOS)和空心松质骨(CC)螺钉固定治疗跟骨骨折。此外,Ilizarov手术是在右脚清创术后进行的.手术后,患者出现髋关节疼痛和髋关节活动受限的主要症状。发起物理治疗以解决这些问题。对结局指标的评估表明关节疼痛减轻,关节活动度显著增强,和肌肉力量的增加。
    Multiple fractures are frequently encountered in adults following road traffic accidents. A 32-year-old male presented with multiple fractures in his right lower extremity, including a femoral shaft fracture, distal third fractures of the tibia and fibula, as well as a calcaneal fracture. The patient provided a history indicative of a road traffic accident. X-rays were performed on both hip joints, both knee joints, and the ankle joints. Treatment involved open reduction and internal fixation (ORIF) with interlocking nailing for the femur, tibia, and fibula, alongside ORIF with plating using a screw-out set (SOS) and cannulated cancellous (CC) screw fixation for the calcaneal fracture. Additionally, the Ilizarov procedure was conducted following debridement over the right foot. Post-surgery, the patient experienced primary symptoms of hip joint pain and restricted hip joint movement. Physiotherapy was initiated to address these issues. Evaluation of outcome measures indicated a reduction in joint pain, significant enhancement in joint mobility, and an increase in muscle strength.
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  • 文章类型: Case Reports
    范可尼综合征(FS)可表现为低磷酸盐血症,肾性糖尿,低尿酸血症和氨基酸尿症。磷酸盐消耗是FS的最关键的临床方面,因为它导致骨软化症。一些患者出现与低磷血症性骨软化症(HO)相关的症状和体征。因此,这些患者出现这些症状并被误诊。通过对已发表文献的调查,发现HO症状是非特异性的,因此在各个中心被误诊。本研究描述了一名46岁的FS男性,该男性患有关节痛并首次被误诊。在他被转诊到提交人的医院后,对他的案件进行了评估,并考虑了评估结果,他被诊断为特发性FS伴多发性骨质疏松性骨折。此外,本研究进行了简短的文献回顾,还讨论了其他误诊的患者病例,这些患者的症状后来被发现是由于HO引起的。希望本研究可以提高医生对HO的认识,并可能有助于引起人们对出现非特异性症状的此类患者的注意。
    Fanconi syndrome (FS) can present with hypophosphatemia, renal glycosuria, hypouricemia and aminoaciduria. Phosphate depletion is the most critical clinical aspect of FS as it leads to osteomalacia. Some patients present with symptoms and signs related to hypophosphatemic osteomalacia (HO). Thus, these patients present with these symptoms and are misdiagnosed. From an investigation of the published literature, HO symptoms are found to be non-specific and were thus misdiagnosed in various centers. The present study describes the case of a a 46-year-old male with FS who suffered from joint pain and was first misdiagnosed. After he was referred to the authors\' hospital, his case was evaluated and following a consideration of the results of this evaluation, he was diagnosed with idiopathic FS with multiple osteoporotic fractures. Furthermore, the present study performs a brief literature review other cases of patients that were misdiagnosed and whose symptoms were later found to be due to HO are also discussed. It is hoped that the present study may increase the awareness of HO among physicians and may help to draw attention to such cases of patients presenting with non-specific symptoms.
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  • 文章类型: Journal Article
    背景:股骨颈骨折(FNF)约占全身所有骨折的3.58%,呈现逐年增长的趋势。根据一项调查,1990年,全世界男性和女性的髋部骨折总数分别约为338,000和917,000.在中国,FNFs占髋部骨折的48.22%。目前,已经对FNF患者的出院后死亡率和死亡风险进行了许多研究.然而,目前尚无关于重症监护病房重症FNF患者院内死亡率及其影响因素的确切研究.
    目的:在本文中,采用3种机器学习方法构建重症监护病房患者院内死亡预测模型,以辅助临床医师早期临床决策。
    方法:使用来自重症监护医学信息集市III的FNF患者的信息进行回顾性分析。在使用合成少数过采样技术算法平衡数据集之后,患者随机分为70%的训练集和30%的测试集进行开发和验证,分别,预测模型。随机森林,极端梯度增强,并以医院死亡为结果构建反向传播神经网络预测模型。使用接收器工作特性曲线下的面积评估模型性能,准确度,精度,灵敏度,和特异性。通过与传统logistic模型的对比,验证了模型的预测价值。
    结果:共选择366名FNFs患者,其中48例(13.1%)住院死亡。通过将数据集与院内死亡组和生存组的平衡为1:1来获得来自636名患者的数据。3种机器学习模型表现出很高的预测精度,和随机森林的接收器工作特性曲线下的面积,极端梯度增强,和反向传播神经网络分别为0.98、0.97和0.95,均具有比传统逻辑回归模型更高的预测性能。对特征变量的重要性进行排名,对预测患者院内死亡风险有意义的前10个特征变量是简化急性生理学评分II,乳酸,肌酐,性别,维生素D,钙,肌酸激酶,肌酸激酶同工酶,白细胞,和年龄。
    结论:利用机器学习构建的死亡风险评估模型对预测重症患者院内死亡率具有积极意义,为降低院内死亡率、改善患者预后提供有效依据。
    BACKGROUND: Femoral neck fracture (FNF) accounts for approximately 3.58% of all fractures in the entire body, exhibiting an increasing trend each year. According to a survey, in 1990, the total number of hip fractures in men and women worldwide was approximately 338,000 and 917,000, respectively. In China, FNFs account for 48.22% of hip fractures. Currently, many studies have been conducted on postdischarge mortality and mortality risk in patients with FNF. However, there have been no definitive studies on in-hospital mortality or its influencing factors in patients with severe FNF admitted to the intensive care unit.
    OBJECTIVE: In this paper, 3 machine learning methods were used to construct a nosocomial death prediction model for patients admitted to intensive care units to assist clinicians in early clinical decision-making.
    METHODS: A retrospective analysis was conducted using information of a patient with FNF from the Medical Information Mart for Intensive Care III. After balancing the data set using the Synthetic Minority Oversampling Technique algorithm, patients were randomly separated into a 70% training set and a 30% testing set for the development and validation, respectively, of the prediction model. Random forest, extreme gradient boosting, and backpropagation neural network prediction models were constructed with nosocomial death as the outcome. Model performance was assessed using the area under the receiver operating characteristic curve, accuracy, precision, sensitivity, and specificity. The predictive value of the models was verified in comparison to the traditional logistic model.
    RESULTS: A total of 366 patients with FNFs were selected, including 48 cases (13.1%) of in-hospital death. Data from 636 patients were obtained by balancing the data set with the in-hospital death group to survival group as 1:1. The 3 machine learning models exhibited high predictive accuracy, and the area under the receiver operating characteristic curve of the random forest, extreme gradient boosting, and backpropagation neural network were 0.98, 0.97, and 0.95, respectively, all with higher predictive performance than the traditional logistic regression model. Ranking the importance of the feature variables, the top 10 feature variables that were meaningful for predicting the risk of in-hospital death of patients were the Simplified Acute Physiology Score II, lactate, creatinine, gender, vitamin D, calcium, creatine kinase, creatine kinase isoenzyme, white blood cell, and age.
    CONCLUSIONS: Death risk assessment models constructed using machine learning have positive significance for predicting the in-hospital mortality of patients with severe disease and provide a valid basis for reducing in-hospital mortality and improving patient prognosis.
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  • 文章类型: Journal Article
    尽管中国人口占世界人口的五分之一,老年人比例较高,骨质疏松症和骨折的患病率较高,有限的研究调查了中国老年人膳食模式与骨密度(BMD)和骨折风险之间的关系.我们的目的是调查不同饮食模式与BMD以及骨折风险之间的关联。老年男女之间的这种联系可能有所不同。
    基于中国骨质疏松症患病率研究,我们纳入了17,489名年龄≥40岁的受试者,他们在中国11个省市的44个县/区随机抽样,完成了食物频率问卷.通过双X射线吸收法测量BMD。使用Genant的半定量技术,根据脊柱侧位X线片定义了椎体骨折。
    富含“食肉”的饮食,\"素食主义者\",“奶制品,水果,卵与全髋关节(TH)较高的BMD显着相关,股骨颈(FN),和腰椎1-4(L1-4)。然而,富含“饮料和油炸食品”的饮食与FN和L1-4的较低BMD相关。食肉饮食的高四分位数与过去5年临床骨折和椎体骨折的风险降低34%-39%相关。在妇女中观察到更强的关联。绝经后妇女的敏感性分析在食肉和素食饮食与高BMD之间表现出更强的正相关。以及食肉饮食和降低骨折风险之间。
    我们的研究表明,富含肉类的饮食,蔬菜,和乳制品,水果,卵可能与更高的骨密度和更低的骨折风险有关,而饮料和油炸食品可能与L1-4的BMD较低有关,尤其是在老年女性中。这些发现有助于为骨质疏松和骨折高危老年人提供饮食营养方面的建议。尤其是绝经后的妇女。
    UNASSIGNED: Despite the fact that China amounts to one-fifth of the world\'s population, has a higher proportion of the elderly, and has a higher prevalence of osteoporosis and fracture, limited studies have investigated the association between dietary patterns and bone mineral density (BMD) as well as fracture risk among the elderly Chinese population. We aimed to investigate the association between different dietary patterns and BMD as well as the risk of fractures, and this association may vary between elderly women and men.
    UNASSIGNED: Building upon the China Osteoporosis Prevalence Study, we included 17,489 subjects aged ≥40 years old randomly sampled across 44 counties/districts of 11 provinces or municipalities in China who completed a food frequency questionnaire. BMD was measured by dual x-ray absorptiometry. Vertebral fracture was defined based on lateral spine radiographs using the semi-quantitative technique of Genant.
    UNASSIGNED: A diet rich in \"carnivorous\", \"vegetarian\", \"dairy, fruit, and egg\" was significantly associated with higher BMD at total hip (TH), femoral neck (FN), and lumbar spine 1-4 (L1-4). Yet, a diet rich in \"beverage and fried food\" was associated with a lower BMD at the FN and L1-4. High quartiles of the carnivorous diet were associated with 34%-39% reduced risk of clinical fracture in the past 5 years and vertebral fracture. Stronger associations were observed among women. Sensitivity analysis among postmenopausal women presented even stronger positive associations between carnivorous and vegetarian diets and high BMD, as well as between carnivorous diet and reduced risk of fractures.
    UNASSIGNED: Our study suggested that a diet rich in meat, vegetables, and dairy, fruit, and eggs might be associated with greater BMD and a lower fracture risk, while beverage and fried foods may be associated with a lower BMD at L1-4, especially among elderly women. These findings are relevant to provide recommendations on dietary nutrition regarding the elderly population at high risk of osteoporosis and fractures, especially postmenopausal women.
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  • 文章类型: Journal Article
    背景:我们使用国家健康与营养调查(NHANES)数据库的二次数据集分析和双样本孟德尔随机化(MR)方法,对吸烟与骨质疏松症和骨质疏松性骨折之间的关系进行了分析。
    方法:使用1999-2018年NHANES数据汇总的单变量和多变量分析,使用加权逻辑回归模型分析吸烟与骨质疏松症或骨质疏松性骨折之间的关系。从IEUOpenGWAS项目中提取了吸烟和骨质疏松症的全基因组关联研究(GWAS)的摘要级数据。采用逆方差加权法作为双样本MR分析的主要方法。
    结果:根据NHANES数据,我们获得了以下主要发现:根据30856名参与者的分析,吸烟与骨质疏松症相关(OR=1.21;95%CI:1.06-1.39,p=0.004);根据30928名参与者的分析,吸烟与髋部骨质疏松性骨折相关(OR=1.47;95%CI:1.14-1.90,根据1.18,p=此外,我们通过两样本MR分析证实了吸烟对骨质疏松性骨折风险的潜在因果效应(OR=24.5;95%CI:1.11-539,p=0.043).
    结论:吸烟与骨质疏松和骨质疏松性骨折的风险增加相关。吸烟对骨质疏松性骨折的风险具有潜在的因果关系。
    BACKGROUND: We conducted analyses of the association between smoking and osteoporosis and osteoporotic fractures using a secondary dataset analysis of the National Health and Nutrition Examination Survey (NHANES) database and the two-sample Mendelian randomization (MR) method.
    METHODS: The associations between smoking and osteoporosis or osteoporotic fractures were analyzed using weighted logistic regression models for both univariate and multivariable analyses using pooled 1999-2018 NHANES data. The summary-level data of genome-wide association studies (GWAS) of smoking and osteoporosis were extracted from the IEU Open GWAS project. The inverse variance weighted method was used as the main method for the two-sample MR analysis.
    RESULTS: We obtained the following main findings based on the NHANES data: smoking was associated with osteoporosis according to the analyses of 30856 participants (OR=1.21; 95% CI: 1.06-1.39, p=0.004); smoking was associated with hip osteoporotic fracture according to the analyses of 30928 participants (OR=1.47; 95% CI: 1.14-1.90, p=0.004); smoking was associated with wrist osteoporotic fracture according to the analyses of 30923 participants (OR=1.33; 95% CI: 1.18-1.49, p<0.001); and smoking was associated with spine osteoporotic fracture according to the analyses of 30910 participants (OR=1.43, 95% CI: 1.18-1.73, p<0.001). In addition, we confirmed the potential causal effect of smoking on the risk of osteoporotic fracture (OR=24.5; 95% CI: 1.11-539, p=0.043) by conducting two-sample MR analyses.
    CONCLUSIONS: Smoking was associated with increased risks of both osteoporosis and osteoporotic fracture. Smoking showed a potential causal effect on the risk of osteoporotic fracture.
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  • 文章类型: Journal Article
    UNASSIGNED: This article aims to evaluate the evolution of radio-graphic parameters (radial tilt, volar tilt, and radial height) of distal radius fractures in patients indicated for conservative treatment at three different times: date of diagnosis, first outpatient visit within 2 weeks after closed reduction, and last outpatient visit.
    UNASSIGNED: We included 84 patients seen at the emergency department of Hospital Municipal Odilon Behrens, with a diagnosis of distal radius fracture and an indication for conservative treatment. We considered only those patients who had serial radiographs taken at least three different times (n=69) in this analysis.
    UNASSIGNED: There was an improvement in radiographic parameters of volar tilt after closed reduction and immobilization, which was maintained until the last outpatient visit. Radial inclination and radial height showed increased values from the first to the second radiographic evaluation and both values had regression when comparing the second to the third (last) evaluation.
    UNASSIGNED: Universal classification stable fractures tend to evolve well with conservative therapy. Level of Evidence II; Development of Diagnostic Criteria in Consecutive Patients (with Gold Standard of Reference Applied).
    UNASSIGNED: O objetivo deste artigo foi avaliar a evolução dos parâmetros radiográficos (inclinação radial, inclinação volar e altura radial) das fraturas da extremidade distal do rádio em pacientes com indicação de tratamento conservador em três momentos diferentes: data do diagnóstico, primeira consulta ambulatorial dentro de. semanas após a redução fechada e última consulta ambulatorial.
    UNASSIGNED: Incluímos 84 pacientes atendidos no departamento de emergência do Hospital Municipal Odilon Behrens, com diagnóstico de fratura distal do rádio e indicação de. conservador. Consideramos nesta análise apenas os pacientes que tiveram radiografias seriadas realizadas pelo menos três vezes diferentes (n=69).
    UNASSIGNED: Houve uma melhora nos parâmetros radiográficos da inclinação volar após a redução fechada e a imobilização, que foi mantida até a última consulta ambulatorial. A inclinação radial e a altura radial apresentaram valores aumentados da primeira para a segunda avaliação radiográfica e ambos os valores tiveram regressão quando comparados da segunda para a terceira (última) avaliação.
    UNASSIGNED: As fraturas estáveis de classificação universal tendem a evoluir bem com a terapia conservadora. Nível de Evidência II; Desenvolvimento de critérios diagnósticos em pacientes consecutivos (com aplicação de referência padrão ouro).
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  • 文章类型: Journal Article
    骨质疏松性骨折会导致严重的健康并发症和死亡风险增加。注册研究可以提供更好的治疗选择,并通过提供有关疾病的有用信息来改善患者的预后。本研究描述了伊朗骨质疏松症登记的协议。
    本注册是一项前瞻性多中心队列研究,招募来自伊朗的骨质疏松症患者。该研究的纳入标准是根据研究的诊断标准诊断出患有原发性或继发性骨质疏松症的个体;将在本注册表中从门诊诊所识别和招募患者。所有诊断为原发性或继发性骨质疏松症的患者都是研究的目标人群。我们的预期样本量为1000名参与者,研究将持续至少2年。伊朗骨质疏松登记处的测量包括四个部分:(i)由特定问卷包测量的变量,(ii)骨矿物质密度(BMD,(iii)临床检查,和(Iv)实验室数据。最终问卷包包括“人口统计信息”,“社会经济地位”,“生活方式”,“生殖健康”,“病史和用药”,“骨质疏松诊断差距”,“骨质疏松的依从性和治疗差距”,“骨折史和跌倒风险评估”,\"FRAX®工具\",“住院和死亡结果”,“腰痛”,“住院史”,“对骨质疏松症的态度”,“骨质疏松症意识”,“骨质疏松症相关表现”,“生活质量(伊朗版SF12问卷)”,和“食物频率问卷(FFQ)”。此注册表的临床检查包括人体测量(包括身高,体重,体重指数(BMI),腰围,臀围,和右腕围),还有血压.基线问卷将在患者被诊断为骨质疏松症后立即填写,然后骨质疏松患者将每年定期随访。在后续访问中,可能随时间变化的变量将被更新。主要成果包括秋季登记,骨折,住院治疗,药物依从性,和死亡。还开发了基于网络的在线用户友好软件用于数据收集。在每次后续行动结束时,将与数据挖掘专家和流行病学家合作进行数据分析。
    伊朗骨质疏松登记处将是有关骨质疏松结果(即骨折,住院治疗,坚持,和国家一级的死亡),其结果将对肌肉骨骼疾病领域的政策制定者非常有益和实用。
    UNASSIGNED: Osteoporotic fractures can result in significant health complications and an increased risk of death. Registry studies could provide better treatment options and improve patient outcomes by providing useful information about the disease. The present study describes the protocol for an osteoporosis registry in Iran.
    UNASSIGNED: This registry is a prospective multicenter cohort study recruiting patients with osteoporosis from Iran. The inclusion criteria of the study are individuals diagnosed with primary or secondary osteoporosis according to the diagnostic criteria of the study; patients will be identified and recruited from outpatient clinics in this registry. All patients diagnosed with primary or secondary osteoporosis are the target population of the study. Our expected sample size is 1000 participants and the study will continue for at least 2 years. The measurements of the Iranian Osteoporosis Registry include four parts: (i) variables measured by the specific questionnaires package, (ii) bone mineral density (BMD, (iii) clinical examination, and (iv) lab data. The final questionnaire package includes \"demographics information\", \"socioeconomic status\", \"lifestyle\", \"reproductive health\", \"medical history and medication\", \"Osteoporosis diagnosis gap\", \"Osteoporosis adherence and treatment gap\", \"fracture history and fall risk assessment\", \"FRAX ® tool \", \"hospitalization and death outcomes\", \"low back pain\", \"hospitalization history\", \"attitude toward osteoporosis\", \"osteoporosis awareness\", \"osteoporosis related-performance\", \"quality of life (Iranian version of SF12 questionnaire )\", and \"food frequency questionnaire (FFQ)\". Clinical examination of this registry includes anthropometric measurements (including height, weight, body mass index (BMI), waist circumference, hip circumference, and right wrist circumference), and blood pressure. The baseline questionnaires will be filled out right after patients are diagnosed with osteoporosis and then osteoporotic patients will be followed up regularly on a yearly basis. In the follow-up visit, variables that may have changed over time are updated. The main outcomes include registration of fall, fracture, hospitalization, medication adherence, and death. An online web-based user-friendly software is also developed for data collection. Data analysis will be conducted with the collaboration of data-mining experts and epidemiologists at the end of each follow-up.
    UNASSIGNED: The Iran Osteoporosis Registry will be a valuable source of information regarding osteoporosis outcomes (i.e. fractures, hospitalizations, adherence, and death at the national level), and its results will be very beneficial and practical for policy makers in the field of musculoskeletal diseases.
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  • 文章类型: Journal Article
    湿式多片离合器中分离板的花键齿断裂会影响车辆的行驶安全性和使用寿命。齿断裂主要是由于齿根处的应力集中和周向载荷分布不均匀引起的。本文考虑了扭矩等参数,牙齿计数,齿形,和错位误差,建立相应的有限元(FE)模型,分析上述参数对隔板强度的影响。在均匀和偏置负载的情况下的分析表明,最佳的齿数和轮廓可以显着增加分离器板的强度,为湿式多片离合器分离板的优化设计提供建议。
    The spline teeth fracture of separator plates in wet multi-plate clutches compromises driving safety and the vehicle\'s lifespan. Tooth fracture is mainly caused by stress concentration at the tooth root and uneven circumferential load distribution. This paper considers parameters such as torque, teeth count, tooth profile, and misalignment errors, establishing the corresponding finite element (FE) model to analyze the impact of the above-mentioned parameters on the strength of the separator plates. Analysis under even and biased load circumstances demonstrated that an optimum tooth count and profile can significantly increase the strength of the separator plates, offering advice for the optimized design of wet multi-plate clutch separator plates.
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