UNASSIGNED:评价我国不同时期肺结核(PTB)通报发病趋势,探讨近年来结核病防控效果。
UNASSIGNED:使用结核病信息管理报告系统(TBIMS)报告的2005年至2020年结核病病例的汇总数据,我们使用Joinpoint回归模型计算了年度百分比变化(APC)。
联合国:从2005年到2020年,中国总共报告了1620万例PTB,平均通知发生率为每10万人75.5。年龄标准化率(ASR)继续从2005年的116.9(/100,000)下降到2020年的47.6(/100,000),年均下降5.6%[APC=-5.6,95%置信区间(CI):-7.0至-4.2]。最小的下降发生在2011-2018年(APC=-3.4,95%CI:-4.6至-2.3),最大的下降发生在2018-2020年(APC=-9.2,95%CI:-16.4至-1.3)。从2005年到2020年,男性的ASR(2005年为159.8/100,000,2020年为72.0/100,000)高于女性(2005年为62.2/100,000,2020年为32.3/100,000),男性平均每年下降6.0%,女性下降4.9%。平均通报发病率在老年人(65岁及以上)中最高(182.3/100,000),平均每年下降6.4%;儿童(0-14岁)最低(4.8/10万),平均每年下降7.3%,但在2014年至2020年期间,显着增加了3.3%(APC=3.3,95%CI:1.4至5.2);中年人(35-64岁)减少了5.8%;青年(15-34岁)的平均年增长率为4.2%。农村地区的平均ASR(81.3/100,000)高于城市地区(76.1/100,000)。农村地区年均下降4.5%,城市地区年均下降6.3%。华南地区的平均ASR最高(103.2/100,000),平均每年下降5.9%,华北地区最低(56.5/10万),年平均下降5.9%。西南部的平均ASR为95.3(/100,000),年降幅最小(APC=-4.5,95%CI:-5.5至-3.5);西北地区平均ASR为100.1(/100,000),年度降幅最大(APC=-6.4,95%CI:-10.0至-2.7);中部,东北,和华东地区平均下降5.2%,6.2%,每年6.1%,分别。
UNASSIGNED:从2005年到2020年,中国的PTB通报发病率持续下降,下降了55%。对于男性等高危人群,老年人,南部的高负担地区,西南,中国西北地区,和农村地区,应加强主动筛查,为确诊病例提供及时有效的抗结核治疗和患者管理服务。也有必要对近年来儿童的上升趋势保持警惕,具体原因有待进一步研究。
UNASSIGNED: To evaluate the trend of notified incidence of pulmonary tuberculosis (PTB) in
China at different periods by population and region and to explore the effect of TB prevention and control in recent years.
UNASSIGNED: Using pooled data on TB cases reported by the TB Information Management Reporting System (TBIMS) from 2005 to 2020, we calculated the annual percentage change (APC) using the Joinpoint regression model.
UNASSIGNED: From 2005 to 2020, a total of 16.2 million cases of PTB were reported in
China, with an average notified incidence of 75.5 per 100,000 population. The age standardization rate (ASR) continued to decline from 116.9 (/100,000) in 2005 to 47.6 (/100,000) in 2020, with an average annual decrease of 5.6% [APC = -5.6, 95% confidence interval ( CI): -7.0 to -4.2]. The smallest decline occurred in 2011-2018 (APC = -3.4, 95% CI: -4.6 to -2.3) and the largest decrease in 2018-2020 (APC = -9.2, 95% CI: -16.4 to -1.3). From 2005 to 2020, the ASR in males (159.8 per 100,000 in 2005, 72.0 per 100,000 in 2020) was higher than that in females (62.2 per 100,000 in 2005, 32.3 per 100,000 in 2020), with an average annual decline of 6.0% for male and 4.9% for female. The average notified incidence was the highest among older adults (65 years and over) (182.3/100,000), with an average annual decline of 6.4%; children (0-14 years) were the lowest (4.8/100,000), with an average annual decline of 7.3%, but a significant increase of 3.3% between 2014 and 2020 (APC = 3.3, 95% CI: 1.4 to 5.2); middle-aged (35-64 years) decreased by 5.8%; and youth (15-34 years) decreased by an average annual rate of 4.2%. The average ASR in rural areas (81.3/100,000) is higher than that in urban areas (76.1/100,000). The average annual decline in rural areas was 4.5% and 6.3% in urban areas. South
China had the highest average ASR (103.2/100,000), with an average annual decline of 5.9%, while North
China had the lowest (56.5/100,000), with an average annual decline of 5.9%. The average ASR in the southwest was 95.3 (/100,000), with the smallest annual decline (APC = -4.5, 95% CI: -5.5 to -3.5); the average ASR in the Northwest China was 100.1 (/100,000), with the largest annual decline (APC = -6.4, 95% CI: -10.0 to -2.7); Central, Northeastern, and Eastern China declined by an average of 5.2%, 6.2%, and 6.1% per year, respectively.
UNASSIGNED: From 2005 to 2020, the notified incidence of PTB in
China continued to decline, falling by 55%. For high-risk groups such as males, older adults, high-burden areas in South, Southwest, and Northwest China, and rural regions, proactive screening should be strengthened to provide timely and effective anti-TB treatment and patient management services for confirmed cases. There is also a necessity to be vigilant about the upward trend of children in recent years, the specific reasons for which need to be further studied.