■脊髓损伤(SCI)是一种神经系统疾病,导致运动和感觉功能障碍低于损伤水平,会导致瘫痪.microRNAs(miRNAs)在SCI治疗中发挥关键作用,相关研究为SCI诊断和治疗提供了见解。文献计量学是文献统计和评价的重要工具,客观地总结多维信息。本研究通过对miRNA和SCI研究的文献计量分析,为未来的合作和临床治疗提供当代资源。
■在这项研究中,我们搜索了WebofScienceCoreCollection(WOSCC)数据库。经过仔细筛选和数据导入,我们提取了年度出版物,引用计数,国家,机构,作者,期刊,被高度引用的文章,共同引用的文章,关键词,和H指数。采用VOSviewer的文献计量学和可视化分析,CiteSpace,R包“参考书”,”和在线分析平台。使用Arrowsmith,我们确定了miRNA-SCI的关系,并讨论了SCI中潜在的miRNA机制.
■从2008年到2024年,相关论文的数量逐年增加,754每年的出版物数量仍然很高,并进入了快速发展的时期。来自50个国家/地区的研究人员802个机构,278期刊,3,867名作者参与了该领域。目前,中国在国家论文数量上有优势,引文,机构,和作者。然而,有必要加强不同作者之间的合作,机构,和国家推动重要学术成果的产生。目前该领域的研究主要集中在神经损伤,凋亡,和基因表达。未来的研究方向主要涉及分子机制,临床试验,外泌体,和炎症反应。
■总的来说,本研究全面分析了SCI中miRNAs的研究现状和前沿。系统的总结提供了对SCI和miRNA之间关系的完整和直观的理解。这些发现为该领域的未来研究和临床应用奠定了基础。
UNASSIGNED: Spinal cord injury (SCI) is a nervous system disease leading to motor and sensory dysfunction below the injury level, and can result in paralysis. MicroRNAs (miRNAs) play a key role in SCI treatment, and related research provides insights for SCI diagnosis and treatment. Bibliometrics is an important tool for literature statistics and evaluation, objectively summarizing multidimensional information. This study comprehensively overviews the field through bibliometric analysis of miRNA and SCI research, providing contemporary resources for future collaboration and clinical treatment.
UNASSIGNED: In this study, we searched the Web of Science Core Collection (WOSCC) database. After careful screening and data import, we extracted annual publications, citation counts, countries, institutions, authors, journals, highly cited articles, co-cited articles, keywords, and H-index. Bibliometrics and visualization analyses employed VOSviewer, CiteSpace, the R package \"bibliometrix,\" and online analytic platforms. Using Arrowsmith, we determined miRNA-SCI relationships and discussed potential miRNA mechanisms in SCI.
UNASSIGNED: From 2008 to 2024, the number of related papers increased annually, reaching 754. The number of yearly publications remained high and entered a period of rapid development. Researchers from 50 countries/regions, 802 institutions, 278 journals, and 3,867 authors participated in the field. Currently,
China has advantages in the number of national papers, citations, institutions, and authors. However, it is necessary to strengthen cooperation among different authors, institutions, and countries to promote the production of important academic achievements. The research in the field currently focuses on
nerve injury, apoptosis, and gene expression. Future research directions mainly involve molecular mechanisms, clinical trials, exosomes, and inflammatory reactions.
UNASSIGNED: Overall, this study comprehensively analyzes the research status and frontier of miRNAs in SCI. A systematic summary provides a complete and intuitive understanding of the relationship between SCI and miRNAs. The presented findings establish a basis for future research and clinical application in this field.