History

History
  • 文章类型: Journal Article
    背景:《秦药》评选结果发布后,“众多的中草药和中成药重新受到关注。Physochlainae(花山神),一种以华山命名的草药,秦岭山脉中突出的山峰,引起了特别的兴趣。尽管如此,整个石竹和秦药的影响仍然被华山的名声所掩盖。
    方法:以“PhysochlainaeRadix”为关键字进行搜索;在中国国家知识基础设施(CNKI)进行搜索,万方数据,WIP数据库,PubMed,WebofScience,和中国国家图书馆数据库。
    结果:本研究通过回顾其历史,概述了Physochlainaeradium,化学成分,制备方法,种植和栽培实践,混合物,生物碱检测,使用禁忌症,资源回收,并预测质量标记。
    结论:为了促进山竹的进一步应用和开发,这项研究还解决了秦药发展中的挑战,并提出了潜在的解决方案。

    BACKGROUND: Upon the release of the selection results of \"Qin Medicine,\" numerous Chinese herbal medicines and proprietary Chinese medicines have regained attention. Physochlainae Radix (Huashanshen), a herbal medicine named after Mount Hua, the prominent peak in the Qinling Mountains, has garnered particular interest. Despite this, the impact of Physochlainae Radix and Qin medicines as a whole remains significantly overshadowed by the renown of Mount Hua.
    METHODS: Search on Using \"Physochlainae Radix\" as the keyword; searches were conducted across China National Knowledge Infrastructure (CNKI), Wanfang Data, WIP Database, PubMed, Web of Science, and the National Library of China databases.
    RESULTS: This study presents an overview of Physochlainae Radix by reviewing its history, chemical composition, preparation methods, planting and cultivation practices, concoctions, alkaloid detection, contraindications for use, resource recycling, and predicting quality markers.
    CONCLUSIONS: To facilitate the further application and development of Physochlainae Radix, this study also addresses the challenges in the development of Qin medicines and proposes potential solutions.

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    文章类型: Journal Article
    目的:了解我国卫生筹资转型的主要特征和历史沿革。
    方法:从各种来源收集数据,包括全球卫生支出数据库(GHED),中国卫生统计年鉴,国家卫生财政年度报告,中国卫生总费用研究报告,etal.进行了描述性统计和文献研究。
    结果:自21世纪初以来,世界上大多数国家都经历了卫生筹资的转变,卫生筹资规模的扩大和公共筹资责任的强化。值得注意的是,我国卫生筹资转型呈现出鲜明的特点。首先,与全球平均水平相比,卫生筹资规模扩大得更快。2000年至2019年期间,人均卫生总费用按可比价格计算增长816.6%,大大超过全球其他国家的平均增长率(102.1%)。其次,为加强公共融资的责任作出了更大的努力。从2000年到2019年,自费卫生支出占卫生总支出的比重大幅下降30.6个百分点。这一下降幅度明显大于全球其他国家的平均下降幅度(5.6个百分点)。第三,政府卫生支出分配模式发生了重大转变,越来越重视“需求方补贴”,超过“供应方补贴”。在“供应方补贴”的范围内,用于医院的资金显着增加,超过了分配给初级医疗机构和公共卫生机构的资金。基于这些鲜明的特点,本文将中国卫生筹资转型扩展为三个维度:规模维度,结构尺寸和流动尺寸。使用全面的分析框架,中国卫生筹资转型的历史大致分为四个阶段:计划经济阶段,经济转型阶段,后非典阶段和新的卫生体制改革阶段。分析了与每个阶段相关的主要特征和进化逻辑。
    结论:最重要的是,应在纵向“嵌入性”和横向“互补性”方面加强卫生筹资体系。此外,应强调卫生筹资过渡在维护隐性价值和减轻公共风险方面的重要性,并且需要一种平衡价值和风险的改进的双向权衡机制。此外,应全面考虑与卫生筹资过渡相关的道德原则,同时在政府实际治理模式内优化预算决策。最后,认识现代医学发展的全局性和深远影响,探索我国卫生筹资转型的长期战略和路径至关重要。
    OBJECTIVE: To comprehend the main characteristics and historical evolution of health financing transition in China.
    METHODS: Data were collected from various sources, including the Global Health Expenditure Database (GHED), China Health Statistics Yearbook, National Health Finance Annual Report, China \' s Total Health Expenditure Research Report, et al. Descriptive statistics and literature study was conducted.
    RESULTS: Since the beginning of the 21st century, most countries in the world had witnessed a transition of health financing, characterized by the expansion of health financing scale and the strengthening of public financing responsibility. Notably, China \' s health financing transition exhibited distinctive features. Firstly, there had been a more rapid expansion in health financing scale compared with global averages. Between 2000 and 2019, total health expenditure per capita experienced a remarkable increase of 816.6% at comparable prices, significantly surpassing average growth rates observed among other countries worldwide (102.1%). Secondly, greater efforts had been made to strengthen the responsibilities of public financing. From 2000 to 2019, there was a substantial decrease of 30.6 percentage points in the proportion of out-of-pocket health expenditure as a share of total health expenditure. This decline was significantly larger than the average reduction observed among other countries worldwide (5.6 percentage points). Thirdly, there had been a significant shift in government health expenditure allocation patterns, with an increased emphasis on \"demand-side subsidies\" surpassing \"supply-side subsidies\". Within the realm of \"supply-side subsidies\", funding directed towards hospitals had notably increased and surpassed that allocated to primary healthcare institutions and public health institutions. Based on these distinctive characteristics, this paper expanded China \' s health financing transition into three dimensions: Scale dimension, structure dimension and flow dimension. Using a comprehensive analytical framework, the history of China \' s health financing transition was roughly divided into four stages: The planned economy stage, the economic transition stage, the post-SARS stage and the new health system reform stage. The main features and evolutionary logic associated with each stage were analyzed.
    CONCLUSIONS: Above all, the health financing system should be enhanced in terms of vertical \"embeddedness\" and horizontal \"complementarity\". Moreover, the significance of health financing transition in preserving hidden value and mitigating public risk should be emphasized, and there is a need for an improved two-way trade-off mechanism that balances value and risk. Additionally, the ethical principles associated with health financing transition should be considered comprehensively, while optimizing budget decision-making within the government \' s actual governance model. Lastly, it is crucial to recognize the overall and profound impact of modern medicine development and explore long-term strategies and pathways for health financing transition in China.
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  • 文章类型: Journal Article
    Twitter(现在是X)上的社交媒体上的帖子,生物人类学新闻(Facebook),和其他场所,以及最近在著名期刊上的出版物,表明灵长类动物学家,生态学家,和其他研究人员正在质疑“旧世界”和“新世界”这两个术语,因为它们的殖民含义和历史。如果这些条款导致消除土著的声音和历史,忽略了土著人民早在欧洲殖民之前就在美洲的事实。语言的使用不是没有语境,但替代术语并不总是显而易见和可用的。从这个角度来看,我们分享一个国际灵长类动物学家小组表达的意见,他们考虑了关于这些术语使用的问题,灵长类动物学家是否应该调整语言使用,以及如何前进。意见的多样性提供了深入了解在灵长类动物研究和保护中使用的常规术语如何影响我们在这些领域的有效性。
    Postings on social media on Twitter (now X), BioAnthropology News (Facebook), and other venues, as well as recent publications in prominent journals, show that primatologists, ecologists, and other researchers are questioning the terms \"Old World\" and \"New World\" due to their colonial implications and history. The terms are offensive if they result in erasing Indigenous voices and history, ignoring the fact that Indigenous peoples were in the Americas long before European colonization. Language use is not without context, but alternative terminology is not always obvious and available. In this perspective, we share opinions expressed by an international group of primatologists who considered questions about the use of these terms, whether primatologists should adjust language use, and how to move forward. The diversity of opinions provides insight into how conventional terms used in primatological research and conservation may impact our effectiveness in these domains.
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  • 文章类型: Journal Article
    真菌杀虫剂是使用真菌细胞的活制剂,如孢子和菌丝,作为活性成分。它们主要包括霉菌杀虫剂,杀菌剂,除草剂和线虫真菌。真菌用于控制农业害虫的利用可以追溯到大约1880年,当时昆虫病原真菌最初用于此目的。然而,直到1965年,世界上第一个杀菌剂,白僵菌,在前苏联注册为Boverin®。在过去的几十年里,已经开发了许多新型的霉菌农药,因为它们的研发成本较低,以及环保和安全的性质。在这次审查中,我们调查了美国的杀虫剂注册情况,欧盟,中国,加拿大和澳大利亚。Superisingly,据发现,近年来注册的杀虫剂数量急剧增加。目前,杀虫剂,杀菌剂(杀线虫剂)和除草剂分别注册了27、53和8个真菌菌株。本文还分析了目前霉菌农药面临的主要问题,并对其未来的发展提出了建议。
    Mycopesticides are living preparations that use fungal cells, such as spores and hyphae, as active ingredients. They mainly include mycoinsecticides, mycofungicides, mycoherbicides and nematophagous fungi. The utilization of fungi for controlling agricultural pests can be traced back to approximately 1880, when entomopathogenic fungi were initially employed for this purpose. However, it was not until 1965 that the world\'s first mycopesticide, Beauveria bassiana, was registered as Boverin® in the former Soviet Union. In past decades, numerous novel mycopesticides have been developed for their lower R&D costs, as well as the environmentally friendly and safe nature. In this review, we investigated the mycopesticides situation of registration in USA, EU, China, Canada and Australia. Superisingly, it was found that the registered mycopesticides are extremely raised in recent years. Currently, the insecticides, fungicides (nematocides) and herbicides were respectively registered 27, 53 and 8 fungal strains. This paper also analyzes the main problems currently faced by mycopesticides and offers suggestions for their future development.
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  • 文章类型: Journal Article
    临床病例研究和报告对于发现新的疾病和医学科学的进步很重要。临床医生和基础科学家都扮演着同样重要的角色,导致治疗方法和症状的发现。在运动障碍领域,临床医生对患者的特殊观察势在必行,不仅对于现象学,而且对于这些疾病的可变发生也是如此,以及其他体征和症状,全天和疾病过程。成立了亚洲运动障碍工作队(TF),以帮助加强和促进该地区运动障碍的合作和研究。作为一个开始,TF回顾了该地区初步描述的运动障碍的原始研究。其中包括在亚洲首次描述的九种疾病-Segawa病,PARK-Parkin,X连锁肌张力障碍-帕金森病(XDP),牙齿-苍白萎缩(DRPLA),伍德豪斯-萨卡蒂综合征,良性成人家族性肌阵挛性癫痫(BAFME),Kufor-Rakeb病,与钙调蛋白结合转录激活因子2(CAMTA2)基因突变相关的震颤性肌张力障碍,和阵发性运动障碍(PKD)。我们希望提供的信息将尊重原始研究人员,并帮助我们学习和理解早期的神经学家和基础科学家如何共同发现新的疾病并在该领域取得进展,影响我们所有人直到今天。
    Clinical case studies and reporting are important to the discovery of new disorders and the advancement of medical sciences. Both clinicians and basic scientists play equally important roles leading to treatment discoveries for both cures and symptoms. In the field of movement disorders, exceptional observation of patients from clinicians is imperative, not just for phenomenology but also for the variable occurrences of these disorders, along with other signs and symptoms, throughout the day and the disease course. The Movement Disorders in Asia Task Force (TF) was formed to help enhance and promote collaboration and research on movement disorders within the region. As a start, the TF has reviewed the original studies of the movement disorders that were preliminarily described in the region. These include nine disorders that were first described in Asia: Segawa disease, PARK-Parkin, X-linked dystonia-parkinsonism, dentatorubral-pallidoluysian atrophy, Woodhouse-Sakati syndrome, benign adult familial myoclonic epilepsy, Kufor-Rakeb disease, tremulous dystonia associated with mutation of the calmodulin-binding transcription activator 2 gene, and paroxysmal kinesigenic dyskinesia. We hope that the information provided will honor the original researchers and help us learn and understand how earlier neurologists and basic scientists together discovered new disorders and made advances in the field, which impact us all to this day.
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  • 文章类型: Journal Article
    中国学者在国际学术界的表现和对国外考古学的研究带来了关于中国考古学国际化的热议。基于中国国家知识基础设施(CNKI)和WebofScience核心收藏(WoS)的数据库,本文收集了中国学者在中国和世界核心期刊(简称CCJ和WCJ)上发表的与考古学有关的论文,然后过滤了CCJ中关于外国考古学的翻译和原创文章,以及WCJs中的所有原始考古文章。使用Excel,CiteSpace和VOSviewer可视化软件,我们分析了这些数据,以鸟瞰中国大陆的考古学研究如何国际化。在上个世纪,中国考古学经历了主动-中断-主动阶段,其特征是向外国学者学习。在过去的二十年里,来自中国大陆的学者在WCJs上发表的文章数量显着增加,大多数研究主题都处于国际奖学金的最前沿。合作网络大大扩展,随着中国大陆主导的文章数量大幅增加。中国大陆研究人员撰写的考古论文出现在更广泛的期刊上,包括那些具有高影响因素的。然而,与中外考古联合项目有关的文章大多发表在CCJ上。中国学者在WCJ上发表的与考古学有关的文章仅占WCJ所有考古学文章的一小部分。与CCJ中的文章相比,中国学者在WCJs上发表的论文数量是沧海一粟。因此,国际化还不是主导趋势,随着新的内向型政策的出台,我们需要更多的时间来观察中国考古学的国际化和本地化趋势。
    Chinese scholars\' performance in international academic community and research on foreign archaeology has brought hot discussion about the internationalization of Chinese archaeology. Based on the databases of the China National Knowledge Infrastructure (CNKI) and the Web of Science core collection (WoS), this paper collected archaeology-related papers published by Chinese scholars in Chinese and world core journals (CCJs and WCJs for short), then filtered translated and original articles about foreign archaeology in CCJs, as well as all original archaeological articles in WCJs. Using Excel, CiteSpace and VOSviewer visualization software, we analyzed these data to give a bird\'s-eye view of how archaeology research in Mainland China has become internationalized. Chinese archaeology has seen active-interrupt-active phases characterized by learning from foreign academics in the last century. Over the past two decades, the number of articles published in WCJs by scholars from Mainland China has increased significantly, and most research topics are at the forefront of international scholarship. Collaboration networks largely expanded, with the number of Mainland China-led articles increasing significantly. Archaeological papers written by researchers from Mainland China have appeared in a more extensive range of journals, including those with high impact factors. However, articles related to joint Sino-foreign archaeological projects were mostly published in CCJs. The archaeology-related articles published by Chinese scholars in WCJs occupied only a small proportion of all archaeological articles in WCJs. Compared to articles in CCJs, the number of those published by Chinese scholars in WCJs is a drop in the ocean. Therefore the internationalization is not yet a dominant trend and with the introduction of the new inward-looking policy we need more time to observe where the trends of internationalization and localization in Chinese archaeology are heading.
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  • 文章类型: English Abstract
    射干麻黄汤已在临床上应用了数千年,是治疗哮喘和其他呼吸系统疾病的经典配方,有通气肺的作用,分散冷,缓解咳嗽和哮喘.本文总结了历史,射干麻黄汤的临床应用及作用机理,并根据Q标记的五项原则预测其质量标记(Q标记)。结果表明,irisflorentin,tectoridin,tectoriginin,irigin,麻黄碱,伪麻黄碱,细辛素,甲基丁香酚,Shionone,epifriedelanol,tussilagone,6-姜辣素,三七碱,卡维丁,Schizandrin,五味子乙素可作为射干麻黄汤的Q标记,为射干麻黄汤的质量控制及后续研究开发提供了依据。
    Shegan Mahuang Decoction has been used in clinical practice for thousands of years, and is a classical formula for treating asthma and other respiratory diseases, with the effects of ventilating lung, dispersing cold, and relieving cough and asthma. This paper summarized the history, clinical application and mechanism of Shegan Mahuang Decoction, and predicted its quality markers(Q-markers) based on the "five principles" of Q-markers. The results suggested that irisflorentin, tectoridin, tectorigenin, irigenin, ephedrine, pseudoephedrine, asarinin, methyleugenol, shionone, epifriedelanol, tussilagone, 6-gingerol, trigonelline, cavidine, schizandrin, and schizandrin B could be used as Q-markers of Shegan Mahuang Decoction, which provided a basis for the quality control and subsequent research and development of Shegan Mahuang Decoction.
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  • 文章类型: Journal Article
    生理盐水(NS)是医学领域中应用最广泛的药剂。然而,从它的起源到它的广泛应用,这仍然是一个谜。此外,关于它的存在是否合理,正在进行辩论,对人体有害,或者将来仍然存在。当前的评论可以追溯到NS的起源,并简要概述了输液的现状。目的通过阐述NS的起源和NS对人体影响的研究现状,可以为将来NS存在的可能性提供一些启示。
    Normal saline (NS) is the most widely used agent in the medical field. However, from its origin to its widespread application, it remains a mystery. Moreover, there is an ongoing debate on whether its existence is reasonable, harmful to the human body, or will still exist in the future. The current review traces back to the origins of NS and provides a brief overview of the current situation of infusion. The purpose may shed some light on the possibility of the existence of NS in the future by elaborating on the origin of NS and the research status of the impact of NS on the human body.
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  • 文章类型: Journal Article
    Cd对农作物的污染是一个世界性问题,需要解决以最大程度地降低人类健康风险。今天,大量研究表明,Si在降低栽培植物中Cd的毒性和积累中起作用。首次讨论了科学认识的演变-土壤和植物中的Cd行为。我们的分析证明,土壤-植物系统中Si-Cd相互作用的研究只是在最近几年才加快,尽管在40-50年前研究了含水系统中硅酸与Cd阳离子之间的基本相互作用。今天,据报道,Si对土壤和植物中Cd的迁移率和易位的影响有许多直接和间接机制。该领域更有成效的研究是将土壤-植物系统视为一个整体的研究。对Cd-Si相关思想发展的分析表明,进一步研究的前景旨在寻找Si和其他物质对土壤-植物系统中Cd行为的协同作用。
    The contamination of crops by Cd is a worldwide problem that needs to be addressed for minimizing risk for human health. Today, numerous investigations have demonstrated that Si plays a role in reducing Cd toxicity and accumulation in cultivated plants. The evolution of scientific understanding - the Cd behavior in soil and in plant is discussed for the first time. Our analysis evidences that the research on Si-Cd interactions in the soil-plant system has quickened only in recent years, although basic interactions between silicic acid and Cd cations in aqueous systems were studied over 40-50 years ago. Today, numerous direct and indirect mechanisms of the Si impact on mobility and translocation of Cd in soil and in plants are reported. More productive studies in this area are those that considered the soil-plant system as a whole. Analysis of the development of the Cd-Si-related ideas suggests the prospects of further studies aimed at finding synergetic action of Si and other substances on Cd behavior in the soil-plant system.
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  • 文章类型: Journal Article
    几十年来,牙科焦虑一直是一种常见的现象。本报告旨在确定研究文献中牙科焦虑的历史根源。搜索了文献数据库WebofScienceCoreCollection,以确定有关该主题的相关论文。使用CRExplorer对收集的文献集进行引用参考分析,一个专门的文献计量软件。这项分析成功地确定了1800年代末和1900年代初有关牙科焦虑症的参考文献。其中包括对牙科焦虑症提供专家意见的文章,报告半结构化访谈以阐明其根本原因,引入心理测量量表来评估牙科焦虑,并从精神分析方面提出了理论和论点。还确定了一些一般涉及焦虑的参考文献。最后,引用的参考分析有助于揭示牙科焦虑研究的历史渊源。这些引用的参考文献为支持后续的牙科焦虑研究提供了具体的基础。
    Dental anxiety has been a common phenomenon under investigation for decades. This report aimed to identify the historical roots of dental anxiety in the research literature. The literature database Web of Science Core Collection was searched to identify relevant papers on this theme. Cited reference analysis on the collected literature set was performed with CRExplorer, a dedicated bibliometric software. This analysis successfully identified the references dealing with dental anxiety in the late 1800s and early 1900s. They included essays that provided expert opinion on dental anxiety, reported semi-structured interviews to elucidate its underlying reasons, introduced psychometric scales to assess dental anxiety, and proposed theories and arguments from psychoanalytic aspects. Several references dealing with anxiety in general were also identified. To conclude, cited reference analysis was useful in revealing the historical origins of dental anxiety research. These cited references provided a concrete foundation to support subsequent dental anxiety research.
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