背景技术伴随衰老有许多生理变化。肌肉收缩减慢,肌肉代谢和神经肌肉接头的改变,神经传导速度(NCV)的降低是这些生理变化之一。本研究旨在阐明性别等生理因素的影响,高度,以及上肢运动和感觉神经传导研究(NCS)的体重指数(BMI),并找出印度中部健康老年受试者的正常数据。方法对印度中部60岁及以上的382名健康成人参与者进行横断面研究。这项研究是在生理学系进行的,AcharyaVinobaBhave农村医院,瓦尔达,印度,从2017年7月到2022年6月。使用NeuronSpectrum5机器(Neurosoft,伊万诺沃,俄罗斯)。MicrosoftExcel电子表格(MicrosoftCorporation,雷德蒙德,华盛顿,美国)被用来将收集到的信息制成表格。为了进行统计分析,IBMSPSSStatisticsforWindows,版本22.0(2013年发布;IBMCorp.,Armonk,纽约,美国)被使用。结果与女性相比,男性的所有NCS参数均较高。随着年龄的增长,较长的远端运动潜伏期(DML)和F波最小潜伏期,减小振幅,观察到传导速度(CV)减慢。随着身高的增加,增加DML和F波的最小延迟,减小振幅,观察到CV的减慢。发现较高的BMI与较低的振幅和CV的减慢有关。结论年龄和身高对波幅有负面影响,CV对DML和F-min潜伏期有正面影响。较高的BMI对振幅和CV有负面影响。
Background There are many physiological changes that accompany aging. Slowing of muscle contraction, alteration of muscle metabolism and neuromuscular junction, and reduction of nerve conduction velocity (NCV) are among these physiological changes. The present
study was conducted to elucidate the effect of physiological factors like gender, height, and Body Mass Index (BMI) on motor and sensory nerve conduction
study (NCS) of the upper limb and find out the normal data for healthy elderly subjects in central India. Methods A cross-sectional
study among 382 healthy adult participants of central India aged 60 years and above. The
study was carried out in the department of Physiology, Acharya Vinoba Bhave Rural Hospital, Wardha, India, from July 2017 to June 2022. An NCS was performed using the Neuron Spectrum 5 machine (Neurosoft, Ivanovo, Russia). A Microsoft Excel spreadsheet (Microsoft Corporation, Redmond, Washington, United States) was used to tabulate the information gathered. For statistical analysis, IBM SPSS Statistics for Windows, Version 22.0 (Released 2013; IBM Corp., Armonk, New York, United States) was used. Results All NCS parameters were greater in males as compared to females. As age advances, longer distal motor latency (DML) and F-wave minimum latency, decreasing amplitude, and slowing of conduction velocity (CV) were observed. As height increases, increasing DML and F-wave minimum latency, decreasing amplitude, and slowing of CV were observed. Higher BMI was found to be associated with lower amplitudes and slowing of CVs. Conclusion Age and height have a negative influence on amplitude and CV is a positive influence on DML and F-min latency. Higher BMI has a negative influence on amplitude and CV.