这项研究的目的是描述与橡子中毒相关的临床数据,并找到与生存相关的变量。纳入了2011年至2018年在CISCO-ONIRIS提供的诊断为橡子中毒的马的数据。诊断基于以下因素:季节,橡子在环境中的存在,提示消化系统/肾脏疾病的临床和血液生化参数,伴侣动物的合并症,和验尸结果。使用Studentt检验进行平均值比较,使用卡方检验进行组比较(p<0.05),完成统计学分析。总共包括25匹马,季节性表明,中毒可能每年都会有所不同。与橡子中毒相关的临床体征是循环休克的体征(嗜睡,心动过速,异常粘膜,呼吸急促),消化体征(腹泻,肠梗阻,绞痛),温度异常。临床病理结果包括血细胞比容增加,WBC,肌酐,BUN,GGT,AST,CK和白蛋白减少。总的来说,44%(11/25)的马存活。大多数(13/14)非幸存者死亡,或者被安乐死,在最初的48小时内。与非生存显着相关的发现是年龄,心率,出血性腹泻,肠梗阻,血细胞比容,肌酐,血乳酸,超声检查时结肠壁厚度。这项研究为橡子中毒病例的马从业者提供了有价值的预后信息。
The aim of this
study is to describe clinical data associated with acorn intoxication and to find variables associated with survival. Data from horses presented at CISCO-ONIRIS from 2011 to 2018 with a diagnosis of acorn intoxication were included. Diagnosis was based on the following: season, the presence of acorns in the environment, clinical and hemato-biochemical parameters suggestive of a digestive/renal disease, the co-morbidity of companion animals, and post-mortem findings. Statistical analysis was completed using Student\'s t-test for mean comparisons and a Chi-square test for group comparisons (p < 0.05). A total of 25 horses were included, and seasonality suggests that the intoxication may vary from year to year. Clinical signs associated with acorn intoxication were signs of circulatory shock (lethargy, tachycardia, abnormal mucous membrane, tachypnea), digestive signs (diarrhea, ileus, colic), and abnormal temperature. Clinical pathological findings included increased hematocrit, WBC, creatinine, BUN, GGT, AST, CK and decreased albumin. Overall, 44% (11/25) of horses survived. The majority (13/14) of non-survivors died, or were euthanized, during the first 48 h. Findings significantly associated with non-survival were age, heart rate, hemorrhagic diarrhea, ileus, hematocrit, creatinine, blood lactate, and thickness of the colon wall at ultrasonography. This
study provides
equine practitioners with valuable prognostic information in cases of acorn intoxication.