PDF(Pubmed)
Abstract：
This study aimed to evaluate the feasibility of transcutaneous auricular vagal nerve stimulation (tAVNS) in healthy horses and its effect on heart rate variability (HRV). The study comprised three phases: the selection of mares, their acclimatization to the tAVNS, and the stimulation phase. Stimulation was performed with two electrodes positioned on the right pinna. The settings were 0.5 mA, 250 μs, and 25 Hz for pulse amplitude, pulse width, and pulse frequency, respectively. HRV was analysed before (B1), during (T), and after (B2) the tAVNS. From the 44 mares initially included, only 7 completed the three phases. In these mares, the heart rate (HR) was significantly lower, and frequency domain parameters showed an increased parasympathetic tone in B2 compared with B1. However, in 3/7 mares, the HR was significantly higher during T compared with B1 and B2, compatible with a decreased parasympathetic tone, while in 4/7 mares, the HR was significantly lower and the parasympathetic nervous system index was significantly higher during T and B2 compared with B1. The tAVNS is an economical and easy procedure to perform and has the potential to stimulate vagal activity; however, it was poorly tolerated in the mares included in this study.
摘要：
本研究旨在评估经皮耳迷走神经刺激（tAVNS）在健康马匹中的可行性及其对心率变异性（HRV）的影响。该研究包括三个阶段：选择母马，他们对tAVNS的适应，和刺激阶段。用位于右耳廓上的两个电极进行刺激。设置为0.5mA，250μs,和25Hz的脉冲幅度，脉冲宽度,和脉冲频率，分别。HRV在(B1)之前进行了分析，在（T）期间，在（B2）tAVNS之后。从最初包括的44匹母马中，只有7个完成了三个阶段。在这些母马中，心率（HR）明显降低，和频域参数显示B2与B1相比，副交感神经张力增加。然而,在3/7母马中，与B1和B2相比，T期间的HR显着升高，与副交感神经张力降低相容，在4/7母马中，与B1相比，T和B2期间的HR显着降低，副交感神经系统指数显着升高。tAVNS是一种经济且易于执行的程序，并且有可能刺激迷走神经活动;然而，在本研究中纳入的母马中耐受性较差.
