多囊卵巢综合征(PCOS),作为育龄妇女最常见的内分泌疾病,受各种因素的影响。因为有证据表明炎症和慢性疾病有关,我们假设在成人人群中,饮食炎症模式评分(EDIP)与PCOS的几率之间存在相关关系.这项病例对照研究是针对伊朗的德黑兰妇女进行的。共有494名参与者(病例组203名PCOS女性,对照组291名健康人),18至45岁,被招募参加这项研究。人口统计信息,人体测量指数,身体活动水平,和饮食摄入量由训练有素的营养学家收集。计算EDIP评分以估计基于18个食物组的总体饮食炎症潜能。使用SPSS版本19进行统计学分析。根据结果,病例组和对照组的平均年龄分别为28.98±5.43和30.15±6.21岁,分别。与健康参与者相比,PCOS患者的EDIP评分差异显著(2.03±1.13vs1.70±0.93,P<.001)。此外,EDIP四分位数间PCOS风险的比值比和95%置信区间显示出显著的直接关系(P=.003).总之,我们的研究表明,PCOS风险与EDIP评分有直接关联.研究结果表明,炎症指数可能是联系饮食和PCOS发展的潜在机制。
Polycystic ovary syndrome (PCOS), as the most common endocrine disorder in women of reproductive age, is influenced by various factors. Because there is evidence linking inflammation with chronic diseases, we hypothesized that there is a relationship between an empirical dietary inflammatory pattern score (EDIP) with odds of PCOS among the adult population. This
case control study was conducted on Tehranian women in Iran. A total of 494 participants (203 women with PCOS in the
case group and 291 healthy people in the control group), aged 18 to 45 years, were recruited for the study. Demographic information, anthropometric indices, physical activity level, and dietary intake were collected by a trained nutritionist. EDIP score was calculated to estimate overall dietary inflammatory potential based on 18 food groups. Statistical analysis was performed with SPSS version 19. Based on the results, the mean age of participants in the
case and control groups were 28.98 ± 5.43 and 30.15 ± 6.21 years, respectively. Individuals with PCOS had a significantly higher difference in EDIP score compared with healthy participants (2.03 ± 1.13 vs 1.70 ± 0.93, P < .001). Also, the odds ratio and 95% confidence interval for the risk of PCOS across quartiles of EDIP showed a significant direct relationship (P = .003). In conclusion, our study showed that there was a direct association between PCOS risk and EDIP score. Findings suggest that inflammatory index might be a potential mechanism linking diet and PCOS development.