背景:黑色素瘤是一种起源于黑素细胞的恶性肿瘤,以其攻击行为和高转移潜力而闻名。近年来,疫苗疗法已成为治疗黑色素瘤的一种有希望的方法,提供靶向和个性化的免疫治疗选择。在这项研究中,我们进行了文献计量学分析,以评估黑色素瘤和疫苗治疗相关出版物的全球研究趋势和影响.
方法:我们使用诸如“黑色素瘤”之类的关键字从过去十年(2013-2023年)的WebofScience数据库中检索了相关文献,“疫苗疗法”,和“癌症疫苗”。我们使用了文献计量指标,包括出版趋势,引文分析,共同作者分析,和期刊分析来评估该领域的研究格局。
结果:筛选后,共有493份出版物被纳入分析.我们发现黑色素瘤和疫苗治疗在癌症免疫治疗领域获得了极大的关注,大量的研究成果和越来越多的引文影响证明了这一点。美国,中国,就出版产出而言,他们的组织是领先的国家/机构,合作研究网络在这一领域很突出。评估黑色素瘤患者疫苗接种治疗的安全性和有效性的临床试验是研究的重点。
结论:这项研究为黑色素瘤疫苗治疗的新研究前景提供了有价值的见解,这可以为未来的研究方向提供信息,并促进该领域研究人员之间的知识交流。
BACKGROUND: Melanoma is a malignant tumor that originates from melanocytes and is known for its aggressive behavior and high metastatic potential. In recent years, vaccine therapy has emerged as a promising approach for the treatment of melanoma, offering targeted and individualized immunotherapy options. In this study, we conducted a bibliometric analysis to assess the global research trends and impact of publications related to melanoma and vaccine therapy.
METHODS: We retrieved relevant literature from the Web of Science database from the past decade (2013-2023) using keywords such as \"melanoma\", \"vaccine therapy\", and \"cancer vaccines\". We used bibliometric indicators including publication trends, citation analysis, co-authorship analysis, and journal analysis to evaluate the research landscape of this field.
RESULTS: After screening, a total of 493 publications were included in the analysis. We found that melanoma and vaccine therapy have gained significant attention in the field of cancer immunotherapy, as evidenced by the numerous research output and increasing citation impact. The United States, China, and their organizations are the leading countries/institutes in terms of publication output, and collaborative research networks are prominent in this field. Clinical trials evaluating the safety and efficacy of vaccination treatment in melanoma patients are the focus of research.
CONCLUSIONS: This study provide valuable insights into the novel research landscape of vaccine treatment of melanoma, which could inform future research directions and facilitate knowledge exchange among researchers in this field.