aneurysmal bone cyst

动脉瘤性骨囊肿
  • 文章类型: Journal Article
    软组织动脉瘤性骨囊肿(STABCs)是在组织病理学上与动脉瘤性骨囊肿相同的罕见肿瘤。这些良性病变的特点是薄,外周骨化和无骨骼连续性。STABC可能难以与骨化性肌炎(MO)和恶性实体从成像和细针穿刺区分。由于稀有和重叠的特点。我们介绍了一例发生在椎旁颈椎肌肉中的STABC。成像,组织病理学,分子分析,和治疗进行了讨论。回顾了其他四例已发表的头颈部STABC病例。
    Soft tissue aneurysmal bone cysts (STABCs) are rare neoplasms histopathologically identical to aneurysmal bone cysts. These benign lesions are characterized by thin, peripheral ossification and no skeletal continuity. STABC may be difficult to distinguish from myositis ossificans (MO) and malignant entities from imaging and fine needle aspiration, due to rarity and overlapping features. We present a case of a STABC occurring in the paraspinal cervical muscles. The imaging, histopathology, molecular analysis, and treatment are discussed. Four other published cases of STABC of the head and neck are reviewed.
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  • 文章类型: Journal Article
    目的:动脉瘤性骨囊肿(ABCs)是骨内良性但侵袭性的血管病变。轨道ABC,虽然罕见,由于视力丧失等衰弱症状的风险,具有临床意义。
    方法:我们的系统评价是根据系统评价和荟萃分析(PRISMA)指南使用PubMed,谷歌学者,Embase,和SCOPUS数据库,以识别和评估探索轨道ABC病例的主要文章。此外,我们提出了一个说明性的病例报告.
    结果:在51项研究的54例中,平均年龄为16.87岁,有23名男性,29名女性,2个未指明。最常见的症状是眼球突出(N=36)和复视(N=21)。关于横向,右轨道最常受到影响(N=27),其次是左轨道(N=21),有四起双边参与的案件。在轨道内,内侧壁最常撞击的位置(N=14),其次是轨道屋顶(N=13),后壁(N=7),侧壁(N=3),和轨道地板(N=2),15起案件涉及多个地点。手术切除是主要的治疗方法,导致44起案件的彻底解决。在我们的案例中,一名30岁的男性患有眼眶动脉瘤样骨囊肿,通过双额开颅联合眼眶上切开术进行病灶切除和眶顶重建手术治疗.
    结论:眼眶中的动脉瘤性骨囊肿可能具有挑战性,并且完全切除病变对于实现最佳的患者预后至关重要。
    OBJECTIVE: Aneurysmal bone cysts (ABCs) are benign but aggressive vascular lesions within bone. Orbital ABCs, though rare, are clinically significant due to the risk of debilitating symptoms such as vision loss.
    METHODS: Our systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines using PubMed, Google Scholar, Embase, and SCOPUS databases to identify and assess primary articles exploring orbital ABC cases. Additionally, we present an illustrative case report.
    RESULTS: Among the 54 cases from the 51 studies included, the mean age was 16.87 years, with 23 males, 29 females, and 2 unspecified. The most prevalent symptoms were exophthalmos (N = 36) and diplopia (N = 21). Regarding laterality, the right orbit was most commonly affected (N = 27), followed by the left orbit (N = 21), with four cases of bilateral involvement. Within the orbit, the medial wall most frequently impacted location (N = 14), followed by the orbital roof (N = 13), posterior wall (N = 7), lateral wall (N = 3), and orbital floor (N = 2), with 15 cases involving multiple locations. Surgical resection was the primary treatment, resulting in complete resolution in 44 cases. In our case, a 30-year-old male with an orbital aneurysmal bone cyst was managed surgically through bifrontal craniotomy with superior orbitotomy for lesion excision and orbital roof reconstruction.
    CONCLUSIONS: Aneurysmal bone cysts in the orbit can be challenging, and complete removal of the lesion is essential for achieving optimal patient outcomes.
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  • 文章类型: Journal Article
    动脉瘤性骨囊肿(ABCs)是罕见的良性骨病变,对长骨干meta端有好感。它们通常是囊性的,膨胀,和溶骨,并可能导致骨畸形。总的来说,关于ABC的最佳治疗仍存在争议;然而,主要由刮宫的组合组成,骨移植,并考虑内固定和截骨术的需要。治疗的目标包括保留骨解剖结构,同时消除病变。关于与良性骨肿瘤相邻的骨关节炎的治疗的文献很少。如果选择全髋关节置换术作为治疗选择,需要勤奋的术前计划,外科医生必须评估病人的骨存量,骨畸形的原因,并根据患者的特征使用特定的植入物和技术。我们介绍了一例患有股骨近端ABC和有症状的相邻髋关节骨关节炎的成年患者,该患者接受了全髋关节置换术的治疗。
    Aneurysmal bone cysts (ABCs) are rare benign bone lesions with a predilection for the metaphysis of long bones. They are often cystic, expansive, and osteolytic and may result in bony deformity. In general, there remains debate about optimal treatment for ABCs; however, the mainstay typically consists of a combination of curettage, bone grafting, and considering the need for internal fixation and osteotomies. The goals of treatment include preserving bony anatomy while eliminating the lesion. There is sparse literature regarding the treatment of osteoarthritis adjacent to benign bony tumors. If total hip arthroplasty is chosen as a treatment option, diligent preoperative planning is required, and the surgeon must assess the patient\'s bone stock, account for bony deformity, and utilize specific implants and techniques based on the patient\'s characteristics. We present a case of an adult patient with proximal femur ABC and symptomatic adjacent hip osteoarthritis who underwent treatment with total hip arthroplasty.
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  • 文章类型: Case Reports
    在胸壁上发展的肿瘤通常很少见。此病例报告强调了罕见的源自第四肋骨前弓的巨细胞瘤。病人,一个21岁的男性,呈现一个膨胀的质量,在八个月的时间里逐渐增加,达到12x8厘米的尺寸。尽管有明显的肿胀,患者报告无相关疼痛或不适,否认有任何体重减轻或外伤史.没有胸痛或心血管症状将这种情况与其他胸壁病变区分开。该报告强调了在胸壁肿块的鉴别诊断中考虑罕见实体如巨细胞瘤的重要性。尤其是在临床表现和患者病史与更常见的情况不一致的情况下。
    Tumors that develop on the chest wall are usually rare. This case report highlights a rare occurrence of a giant cell tumor originating from the anterior arch of the fourth rib. The patient, a 21-year-old male, presented with a bulging mass that had been gradually increasing in size over an eight-month period, reaching dimensions of 12 x 8 cm. Despite the noticeable swelling, the patient reported no associated pain or discomfort and denied any history of weight loss or trauma. The absence of chest pain or cardiovascular symptoms distinguished this case from other chest wall pathologies. This report underscores the importance of considering rare entities such as giant cell tumors in the differential diagnosis of chest wall masses, especially in cases where clinical presentation and patient history do not align with more common conditions.
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    文章类型: Case Reports
    动脉瘤性骨囊肿(ABC)具有侵袭性,膨胀性,和局部破坏性血管病变。目前尚不清楚ABCs的确切病因,据推测与血管畸形或骨血管破坏有关。迄今为止,目前还没有关于阴茎内翻阴道成形术(PIV)后发生耻骨ABCs的报道.
    本报告描述了先前接受过PIV的跨性别患者的公共ABC的发展,可能表明这种性别确认手术非常罕见的并发症。
    一名37岁的变性人女性最初被转诊到骨科肿瘤诊所,以评估12个月的左髋和腹股沟疼痛病史。她在演讲前约19个月接受了性别确认PIV。增强磁共振成像(MRI)显示,左耻骨上支的T1信号强度低,T2高强度不均匀7.5×4.9×4.3cm破坏性肿块,延伸穿过耻骨联合进入右耻骨上支。针芯骨活检显示出可变的细胞纺锤体和圆形病变,并伴有类骨质形成和局灶性坏死。细胞对CD34、S100和结蛋白呈阴性。没有证据表明骨肉瘤,最终审查赞成ABC的诊断。鉴于质量的高度破坏性,它被切除了,用生物真皮网重建伤口。
    尽管在这种情况下无法区分巧合和因果关系,患者最近的PIV和附近骨骼中罕见的ABC的发展值得本报告中的推测和讨论。
    UNASSIGNED: Aneurysmal bone cysts (ABCs) are aggressive, expansile, and locally destructive vascular lesions. The exact etiology of ABCs is currently unknown and hypothesized to be related to vascular malformations or disruption of osseous vascularity. To date, there have been no reports describing the development of pubic ABCs following penile inversion vaginoplasty (PIV).
    UNASSIGNED: This report describes the development of a pubic ABC in a transgender patient who had previously undergone PIV, possibly indicating a very rare complication of this gender-affirming operation.
    UNASSIGNED: A 37-year-old transgender female was initially referred to the orthopedic oncology clinic for evaluation of a 12-month history of left hip and groin pain. She had undergone gender-affirming PIV about 19 months prior to presentation. Magnetic resonance imaging (MRI) with contrast revealed a low T1 signal intensity and heterogenous T2 hyperintensity 7.5 × 4.9 × 4.3-cm destructive mass in the left superior pubic ramus extending across the pubic symphysis into the right superior pubic ramus. A needle core bone biopsy demonstrated a variably cellular spindle and round lesion with islands of osteoid formation and focal necrosis. The cells were negative for CD34, S100, and desmin. There was no evidence suggesting osteosarcoma, and final review favored the diagnosis of an ABC. Given the highly destructive nature of the mass, it was resected, and the resulting wound was reconstructed with a biologic dermal mesh.
    UNASSIGNED: Although it is impossible to distinguish coincidence from causation in this case, the patient\'s recency of PIV and development of a rare ABC in a nearby bone warrants the speculation and discussion provided in this report.
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  • 文章类型: Journal Article
    背景:动脉瘤性骨囊肿(ABCs)是良性的,长骨中可能发生的溶骨性病变,椎骨,或者很少,头骨。在这里,作者介绍了一名15岁男性的左额顶颅骨原发性ABC的病例,并回顾了文献,以深入了解这种罕见疾病的性质。
    方法:一名健康的15岁男性表现出紧张,左额顶头皮疼痛病变。他无法识别任何煽动创伤,但在出现前不到2周首先注意到病变逐渐增大。颅骨成像显示颅骨溶解性病变,液体水平提示ABC。通过广泛切除病变并重建颅骨缺损提供治疗。这没有并发症,组织病理学评估证实了原发性ABC的诊断。
    结论:颅骨的ABCs是罕见实体,最常见于颅底和颅骨。通常,这些病变与潜在的骨病理学(继发性ABCs)相关,但很少见到孤立性病变(原发性ABCs).临床管理包括切除和适当的基础病理的辅助治疗。
    BACKGROUND: Aneurysmal bone cysts (ABCs) are benign, osteolytic lesions that can occur in long bones, vertebrae, or rarely, the skull. Here the authors present the case of a 15-year-old male with a primary ABC of the left frontoparietal skull along with a review of the literature to provide insight into the nature of this rare disease.
    METHODS: An otherwise healthy 15-year-old male presented with a tense, painful lesion of the left frontoparietal scalp. He could not identify any inciting trauma, but first noted the lesion less than 2 weeks prior to presentation with progressive enlargement. Cranial imaging revealed a lytic skull lesion with fluid-fluid levels suggestive of ABC. Curative therapy was provided via wide excision of the lesion and calvarial reconstruction of the resultant skull defect. This was performed without complication, and histopathological evaluation confirmed the diagnosis of primary ABC.
    CONCLUSIONS: ABCs of the skull are rare entities and most often arise in the skull base versus the calvaria. Typically, these lesions are associated with an underlying bone pathology (secondary ABCs) but can be rarely seen as isolated lesions (primary ABCs). Clinical management consists of excision and adjuvant therapy for underlying pathology where appropriate.
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  • 文章类型: Case Reports
    动脉瘤样骨囊肿(ABC)是一种不寻常的,非癌性骨病变的特征是其溶解性(导致骨丢失),出血性,扩大自然。ABC比较少见,只占所有骨肿瘤的1%。这些囊肿通常在长骨和脊柱中发现,但在meta骨很少见。使这种情况非常罕见。
    在此案例报告中,我们介绍了一例26岁女性的第3meta骨ABC病例,主诉长期脚痛,脚背肿胀逐渐增加。放射学评估后,她接受了组织病理学评估。对meta骨和肿瘤块进行了整体切除,并用同侧腓骨支柱移植物代替了间隙。切除组织的组织病理学检查提示ABC,没有任何恶性肿瘤的证据。在1年的随访结束时,她现在完全无痛与完整的ROM的脚和脚踝。
    本研究旨在描述一个meta骨ABC的病例,这种情况不仅带来了诊断上的困境,而且对病变的管理也构成了挑战。
    UNASSIGNED: An aneurysmal bone cyst (ABC) is an unusual, non-cancerous bone lesion that is characterized by its lytic (causing bone loss), hemorrhagic, and expanding nature. ABCs are relatively rare, making up only 1% of all bone tumors. These cysts are typically found in long bones and the spine but are very rarely seen in the metatarsal bones, making such occurrences quite uncommon.
    UNASSIGNED: In this case report, we present a case of ABC of the 3rd metatarsal in a 26-year-old female with complaints of long-standing foot pain and gradually increasing swelling of the dorsum of the foot. After radiological evaluation, she had undergone histopathological evaluation. An en bloc resection of the metatarsal along with the tumor mass was performed and the gap was replaced with an ipsilateral fibular strut graft. Histopathological examination of the resected tissue was suggestive of ABC without any evidence of malignancy. At the end of 1 year of follow-up, she is now completely pain free with intact rom of foot and ankle.
    UNASSIGNED: The present study aims to describe a case of ABC of the metatarsal, a condition that not only poses a diagnostic dilemma but also constitutes a challenge in the management of lesion.
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  • 文章类型: Case Reports
    脊柱动脉瘤性骨囊肿(ABC)很少见,组织学上的良性肿瘤具有攻击行为,这可能会导致骨骼和软组织的破坏,特别是影响神经元素。这些肿瘤的管理,包括治疗方式和后续方案,仍然具有挑战性。
    一名7岁男孩在入院前出现胸壁疼痛持续两个月,在入院前10天伴有进行性单纯性轻瘫。检查期间脊髓病征象明显。影像学检查证实了T6级多囊性病变,涉及椎骨的后部元素,有明显的脊髓压缩。由于神经功能恶化,他接受了紧急椎板切除术和神经减压术,其次是肿瘤次全切除。术后组织病理学检查证实了ABC的诊断,患者经历了显著的神经系统恢复。然而,21天后,患者因重度轻瘫再次进入急诊科。磁共振成像显示残留肿瘤快速生长,导致绳索压缩。他接受了积极的全肿瘤切除术,T6椎体全切术,用椎弓根螺钉和笼子插入固定。第二次手术后,迅速恢复神经系统。
    这份罕见病例报告强调了在儿科人群中对脊柱ABC进行密切随访的重要性。它强调了管理这些肿瘤的挑战,以及需要警惕监测以检测和解决快速复发。
    UNASSIGNED: Spinal aneurysmal bone cysts (ABCs) are rare, histologically benign tumors with aggressive behavior, which may cause bone and soft-tissue destruction, particularly affecting neural elements. Management of these tumors, including treatment modalities and follow-up protocols, remains challenging.
    UNASSIGNED: A 7-year-old boy presented with chest wall pain persisting for two months before admission, accompanied by progressive mono paresis lasting ten days before admission. Myelopathy signs were evident during the examination. Imaging confirmed a multicystic lesion at the T6 level involving the posterior elements of the vertebra, with significant cord compression. Due to deteriorating neurological function, he underwent urgent laminectomy and neural decompression, followed by subtotal tumor resection. Postoperative histopathological examination confirmed the diagnosis of an ABC, and the patient experienced significant neurological recovery. However, after 21 days, the patient was readmitted to the emergency department with severe paraparesis. Magnetic resonance imaging revealed rapid growth of the residual tumor, leading to cord compression. He underwent aggressive total tumor resection, T6 vertebral body corpectomy, and fixation with pedicle screws and cage insertion. Following the second surgery, prompt neurological recovery occurred.
    UNASSIGNED: This rare case report emphasizes the importance of a close follow-up protocol for spinal ABCs in the pediatric population. It highlights the challenges in managing these tumors and the need for vigilant monitoring to detect and address rapid recurrences.
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  • 文章类型: Case Reports
    背景:动脉瘤样骨囊肿(ABC)并不常见,良性,血管多囊性骨病变,在生命的头二十年中最常见。长骨的干phy端,骨盆,和脊柱是最常见的位置。ABCs形成的确切潜在病理生理学仍不清楚;然而,据信创伤或血管紊乱后的反应过程可能起重要作用。颅底受累很少发生,颅内ABCs的患病率高达5%。
    方法:一位18岁的青春期女性,三个月前出现了进行性视力模糊的病史。脑和眼眶MRI未见异常发现。糖皮质激素治疗三个月后,诊断为多发性硬化症,左眼视力障碍突然恶化。该患者接受了MRI检查,影像学研究表明,前斜突有明确的30×22×20-mm病变,并延伸到视神经管和筛窦。病人接受了翼点开颅手术,肿瘤被切除了.组织病理学检查提示ABC。
    结论:对于早期单侧视力下降的年轻人,应考虑ABC和其他情况,并应在早期和随访期间进行影像学检查。
    BACKGROUND: Aneurysmal bone cyst (ABC) is an uncommon, benign, vascular multicystic bony lesion that most frequently develops in the first two decades of life. The metaphysis of long bones, pelvic, and vertebral column are the most common locations. The precise underlying pathophysiology of ABCs formation remains unclear; however, it is believed that reactive processes subsequent to trauma or vascular disturbance may play an important role. Involvement of the skull base rarely occurs with a prevalence of up to 5% of intracranial ABCs.
    METHODS: An 18-year-old adolescent female with a history of progressive blurred vision since three months ago presented to our office. The brain and orbital MRI demonstrated no abnormal findings. After three months of glucocorticoid treatment with the diagnosis of multiple sclerosis, the visual impairment of the left eye deteriorated abruptly. The patient underwent an MRI and the imaging study demonstrated a well-defined 30 × 22 × 20-mm lesion at the anterior clinoid process with an extension to the optic canal and ethmoid sinus. The patient underwent pterional craniotomy, and the tumor was resected. The histopathological examination was suggestive of ABC.
    CONCLUSIONS: ABC and other conditions should be considered in young-age people with an early unilateral decline in vision and imaging studies should be obtained in early stages and during follow-ups.
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  • 文章类型: Journal Article
    目的:我们报告了一例纤维发育不良(FD)伴动脉瘤样骨囊肿(ABC)样改变的儿童眼眶受累,审查相关案件,并讨论临床特征,治疗,和这种疾病的预后。
    方法:一名10岁女孩右眼球突出(眼球突出程度:OD16mm,OS13mm)和有限的视力(视力:OD1.0,OS0.8),无外伤。术前CT显示右侧颅眶交通瘤5.0*4.3cm。MRI显示明确的多囊性肿块,流体水平分散,肥皂泡样改变。患儿接受了全肿瘤切除和眶壁钛网重建。在20个月的随访中,孩子已经从眼部问题中恢复过来,肿瘤没有复发.
    结论:FD合并ABC很少发生在眼眶,通常以眼部症状开始。病因尚不确定。早期诊断和手术至关重要。建议尽可能完全切除,因为残留病变可能会复发。
    OBJECTIVE: We report a case of fibrous dysplasia (FD) with aneurysmal bone cyst (ABC)-like change in a child with orbital involvement, review the related cases, and discuss clinical features, therapy, and prognosis of this disease.
    METHODS: A 10-year-old girl had right proptosis (degree of exophthalmos: OD 16 mm, OS 13 mm) and limited vision (visual acuity: OD 1.0, OS 0.8) without trauma. Preoperative CT showed a 5.0*4.3 cm right-sided crania-orbital communicating tumor. MRI indicated a well-defined multicystic mass with scattered fluid levels and soap bubble-like alterations. The child underwent total tumor resection and orbital parietal titanium mesh reconstruction. At 20 months of follow-up, the child has recovered from ocular problems, and the tumor has not recurred.
    CONCLUSIONS: FD combined with ABC rarely occurs in orbit and generally begins with ocular symptoms. The etiology is uncertain. Early diagnosis and surgery are essential. Complete resection is suggested whenever possible because residual lesions may recur.
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