aneurysmal bone cyst

动脉瘤性骨囊肿
  • 文章类型: Journal Article
    软组织动脉瘤性骨囊肿(STABCs)是在组织病理学上与动脉瘤性骨囊肿相同的罕见肿瘤。这些良性病变的特点是薄,外周骨化和无骨骼连续性。STABC可能难以与骨化性肌炎(MO)和恶性实体从成像和细针穿刺区分。由于稀有和重叠的特点。我们介绍了一例发生在椎旁颈椎肌肉中的STABC。成像,组织病理学,分子分析,和治疗进行了讨论。回顾了其他四例已发表的头颈部STABC病例。
    Soft tissue aneurysmal bone cysts (STABCs) are rare neoplasms histopathologically identical to aneurysmal bone cysts. These benign lesions are characterized by thin, peripheral ossification and no skeletal continuity. STABC may be difficult to distinguish from myositis ossificans (MO) and malignant entities from imaging and fine needle aspiration, due to rarity and overlapping features. We present a case of a STABC occurring in the paraspinal cervical muscles. The imaging, histopathology, molecular analysis, and treatment are discussed. Four other published cases of STABC of the head and neck are reviewed.
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  • 文章类型: Journal Article
    目的:动脉瘤性骨囊肿(ABCs)是骨内良性但侵袭性的血管病变。轨道ABC,虽然罕见,由于视力丧失等衰弱症状的风险,具有临床意义。
    方法:我们的系统评价是根据系统评价和荟萃分析(PRISMA)指南使用PubMed,谷歌学者,Embase,和SCOPUS数据库,以识别和评估探索轨道ABC病例的主要文章。此外,我们提出了一个说明性的病例报告.
    结果:在51项研究的54例中,平均年龄为16.87岁,有23名男性,29名女性,2个未指明。最常见的症状是眼球突出(N=36)和复视(N=21)。关于横向,右轨道最常受到影响(N=27),其次是左轨道(N=21),有四起双边参与的案件。在轨道内,内侧壁最常撞击的位置(N=14),其次是轨道屋顶(N=13),后壁(N=7),侧壁(N=3),和轨道地板(N=2),15起案件涉及多个地点。手术切除是主要的治疗方法,导致44起案件的彻底解决。在我们的案例中,一名30岁的男性患有眼眶动脉瘤样骨囊肿,通过双额开颅联合眼眶上切开术进行病灶切除和眶顶重建手术治疗.
    结论:眼眶中的动脉瘤性骨囊肿可能具有挑战性,并且完全切除病变对于实现最佳的患者预后至关重要。
    OBJECTIVE: Aneurysmal bone cysts (ABCs) are benign but aggressive vascular lesions within bone. Orbital ABCs, though rare, are clinically significant due to the risk of debilitating symptoms such as vision loss.
    METHODS: Our systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines using PubMed, Google Scholar, Embase, and SCOPUS databases to identify and assess primary articles exploring orbital ABC cases. Additionally, we present an illustrative case report.
    RESULTS: Among the 54 cases from the 51 studies included, the mean age was 16.87 years, with 23 males, 29 females, and 2 unspecified. The most prevalent symptoms were exophthalmos (N = 36) and diplopia (N = 21). Regarding laterality, the right orbit was most commonly affected (N = 27), followed by the left orbit (N = 21), with four cases of bilateral involvement. Within the orbit, the medial wall most frequently impacted location (N = 14), followed by the orbital roof (N = 13), posterior wall (N = 7), lateral wall (N = 3), and orbital floor (N = 2), with 15 cases involving multiple locations. Surgical resection was the primary treatment, resulting in complete resolution in 44 cases. In our case, a 30-year-old male with an orbital aneurysmal bone cyst was managed surgically through bifrontal craniotomy with superior orbitotomy for lesion excision and orbital roof reconstruction.
    CONCLUSIONS: Aneurysmal bone cysts in the orbit can be challenging, and complete removal of the lesion is essential for achieving optimal patient outcomes.
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  • 文章类型: Journal Article
    动脉瘤性骨囊肿(ABCs)是罕见的良性骨病变,对长骨干meta端有好感。它们通常是囊性的,膨胀,和溶骨,并可能导致骨畸形。总的来说,关于ABC的最佳治疗仍存在争议;然而,主要由刮宫的组合组成,骨移植,并考虑内固定和截骨术的需要。治疗的目标包括保留骨解剖结构,同时消除病变。关于与良性骨肿瘤相邻的骨关节炎的治疗的文献很少。如果选择全髋关节置换术作为治疗选择,需要勤奋的术前计划,外科医生必须评估病人的骨存量,骨畸形的原因,并根据患者的特征使用特定的植入物和技术。我们介绍了一例患有股骨近端ABC和有症状的相邻髋关节骨关节炎的成年患者,该患者接受了全髋关节置换术的治疗。
    Aneurysmal bone cysts (ABCs) are rare benign bone lesions with a predilection for the metaphysis of long bones. They are often cystic, expansive, and osteolytic and may result in bony deformity. In general, there remains debate about optimal treatment for ABCs; however, the mainstay typically consists of a combination of curettage, bone grafting, and considering the need for internal fixation and osteotomies. The goals of treatment include preserving bony anatomy while eliminating the lesion. There is sparse literature regarding the treatment of osteoarthritis adjacent to benign bony tumors. If total hip arthroplasty is chosen as a treatment option, diligent preoperative planning is required, and the surgeon must assess the patient\'s bone stock, account for bony deformity, and utilize specific implants and techniques based on the patient\'s characteristics. We present a case of an adult patient with proximal femur ABC and symptomatic adjacent hip osteoarthritis who underwent treatment with total hip arthroplasty.
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  • 文章类型: Journal Article
    背景:动脉瘤性骨囊肿(ABCs)是溶骨性的,非恶性,骨的血管病变。病理性骨折可能是ABCs的表现,发生在约8%的ABC中。文献中已经描述了不同的治疗方法,但是,如今,ABCs患者病理性骨折的最佳治疗仍存在争议,目前尚无标准的治疗指南,也没有关于最佳手术干预的共同指征.我们研究的目的是回顾有关此问题的现有文献,探索和面对ABC中病理性骨折的不同手术治疗方法,以阐明这些患者的手术方法。方法:对PubMed索引的文献进行系统回顾,MEDLINE,并进行了Cochrane图书馆数据库。遵循系统审查和荟萃分析(PRISMA)的首选报告项目。结果:共有37篇相关文章最终纳入研究。总的来说,我们达到了140名患者。在纳入审查的140名患者中,124例患者(88.6%)接受了刮宫手术,15例(10.7%)患者行整块切除手术。共有47%的患者(70)接受了钢板的综合手术,螺钉,钉,或外固定器。8.6%的患者使用辅助治疗(12)。并发症涉及20.7%的患者(29)。结论:总之,动脉瘤性骨囊肿病理性骨折的治疗需要仔细的患者评估,考虑到年龄等因素,开放生长板的存在,病变的位置,和外科医生的专业知识。
    Background: Aneurysmal bone cysts (ABCs) are osteolytic, non-malignant, vascular lesions of the bone. Pathological fractures can be a manifestation of the ABCs, which occur in about 8% of ABCs. Different treatments have been described in the literature, but, nowadays, an optimal management of the pathological fractures in patients with ABCs is still a matter of debate and there are no standard guidelines for treatment nor any shared indication about the best surgical intervention. The aim of our study is to review the current literature available on this matter exploring and confronting different surgical treatments for pathological fractures in ABC in order to clarify the surgical approach to these patients. Methods: A systematic review of the literature indexed in PubMed, MEDLINE, and Cochrane Library databases was carried out. The Preferred Reporting Items for Systematically Reviews and Meta-Analyses (PRISMA) were followed. Results: A total of 37 articles were relevant and were finally included in the study. In total, we reached a population of 140 patients. Of the 140 patients included in the review, 124 patients (88.6%) underwent curettage surgery, 15 patients (10.7%) underwent en bloc resection surgery. A total of 47% of patients (70) underwent synthesis surgery with a plate, screw, nail, or external fixator. Adjuvant treatments were used in 8.6% of patients (12). Complications involved 20.7% of the patients (29). Conclusions: In conclusion, the treatment of pathological fractures in aneurysmal bone cysts requires careful patient assessment, considering factors such as age, the presence of open growth plates, the location of the lesion, and the surgeon\'s expertise.
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  • 文章类型: Case Reports
    脊柱动脉瘤性骨囊肿(ABC)很少见,组织学上的良性肿瘤具有攻击行为,这可能会导致骨骼和软组织的破坏,特别是影响神经元素。这些肿瘤的管理,包括治疗方式和后续方案,仍然具有挑战性。
    一名7岁男孩在入院前出现胸壁疼痛持续两个月,在入院前10天伴有进行性单纯性轻瘫。检查期间脊髓病征象明显。影像学检查证实了T6级多囊性病变,涉及椎骨的后部元素,有明显的脊髓压缩。由于神经功能恶化,他接受了紧急椎板切除术和神经减压术,其次是肿瘤次全切除。术后组织病理学检查证实了ABC的诊断,患者经历了显著的神经系统恢复。然而,21天后,患者因重度轻瘫再次进入急诊科。磁共振成像显示残留肿瘤快速生长,导致绳索压缩。他接受了积极的全肿瘤切除术,T6椎体全切术,用椎弓根螺钉和笼子插入固定。第二次手术后,迅速恢复神经系统。
    这份罕见病例报告强调了在儿科人群中对脊柱ABC进行密切随访的重要性。它强调了管理这些肿瘤的挑战,以及需要警惕监测以检测和解决快速复发。
    UNASSIGNED: Spinal aneurysmal bone cysts (ABCs) are rare, histologically benign tumors with aggressive behavior, which may cause bone and soft-tissue destruction, particularly affecting neural elements. Management of these tumors, including treatment modalities and follow-up protocols, remains challenging.
    UNASSIGNED: A 7-year-old boy presented with chest wall pain persisting for two months before admission, accompanied by progressive mono paresis lasting ten days before admission. Myelopathy signs were evident during the examination. Imaging confirmed a multicystic lesion at the T6 level involving the posterior elements of the vertebra, with significant cord compression. Due to deteriorating neurological function, he underwent urgent laminectomy and neural decompression, followed by subtotal tumor resection. Postoperative histopathological examination confirmed the diagnosis of an ABC, and the patient experienced significant neurological recovery. However, after 21 days, the patient was readmitted to the emergency department with severe paraparesis. Magnetic resonance imaging revealed rapid growth of the residual tumor, leading to cord compression. He underwent aggressive total tumor resection, T6 vertebral body corpectomy, and fixation with pedicle screws and cage insertion. Following the second surgery, prompt neurological recovery occurred.
    UNASSIGNED: This rare case report emphasizes the importance of a close follow-up protocol for spinal ABCs in the pediatric population. It highlights the challenges in managing these tumors and the need for vigilant monitoring to detect and address rapid recurrences.
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  • 文章类型: Journal Article
    目的:我们报告了一例纤维发育不良(FD)伴动脉瘤样骨囊肿(ABC)样改变的儿童眼眶受累,审查相关案件,并讨论临床特征,治疗,和这种疾病的预后。
    方法:一名10岁女孩右眼球突出(眼球突出程度:OD16mm,OS13mm)和有限的视力(视力:OD1.0,OS0.8),无外伤。术前CT显示右侧颅眶交通瘤5.0*4.3cm。MRI显示明确的多囊性肿块,流体水平分散,肥皂泡样改变。患儿接受了全肿瘤切除和眶壁钛网重建。在20个月的随访中,孩子已经从眼部问题中恢复过来,肿瘤没有复发.
    结论:FD合并ABC很少发生在眼眶,通常以眼部症状开始。病因尚不确定。早期诊断和手术至关重要。建议尽可能完全切除,因为残留病变可能会复发。
    OBJECTIVE: We report a case of fibrous dysplasia (FD) with aneurysmal bone cyst (ABC)-like change in a child with orbital involvement, review the related cases, and discuss clinical features, therapy, and prognosis of this disease.
    METHODS: A 10-year-old girl had right proptosis (degree of exophthalmos: OD 16 mm, OS 13 mm) and limited vision (visual acuity: OD 1.0, OS 0.8) without trauma. Preoperative CT showed a 5.0*4.3 cm right-sided crania-orbital communicating tumor. MRI indicated a well-defined multicystic mass with scattered fluid levels and soap bubble-like alterations. The child underwent total tumor resection and orbital parietal titanium mesh reconstruction. At 20 months of follow-up, the child has recovered from ocular problems, and the tumor has not recurred.
    CONCLUSIONS: FD combined with ABC rarely occurs in orbit and generally begins with ocular symptoms. The etiology is uncertain. Early diagnosis and surgery are essential. Complete resection is suggested whenever possible because residual lesions may recur.
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  • 文章类型: Case Reports
    动脉瘤性骨囊肿(ABCs)是良性的,由多个充血腔组成的非肿瘤性囊性病变,它们被结缔组织间隔隔开,它们占所有颅骨和颌骨病变病例的约6%和1.5%,分别。
    这里,介绍了一例80岁男性,经组织学证实诊断为ABC,涉及左下颌骨。患者在使用矫形器造影术确认诊断后接受了部分颌骨切除术,计算机断层扫描,还有组织活检.随访1年后患者无疼痛,对照体位造影显示无复发迹象.随后用钛板和左股骨外侧三分之二的一块骨头重建了骨的愈合部分,此后他的美容状况良好。
    ABCs患者存在扩张性和放射性骨病变,这可能与牙槽骨侵蚀引起的牙齿移位和脱落有关。为了预防复发和发病率增加,必须完全切除病变。
    涉及颌骨的ABCs极为罕见,并且更有可能构成诊断挑战,因为它们在临床上更有可能与其他扩张性放射性骨病变(如成釉细胞瘤)混淆。成骨细胞瘤,和巨细胞瘤等等。此外,大量骨基质形成的患者有时会在组织学上与包括骨肉瘤在内的其他骨形成肿瘤相混淆。复发是常见的,但可以通过完全切除病变来避免或减少复发。
    UNASSIGNED: Aneurysmal bone cysts (ABCs) are benign, non-neoplastic cystic lesions composed of multiple blood-filled cavities, which are separated by connective tissue septa and they constitute ~6 and 1.5% of all cases of the skull and jaws lesions, respectively.
    UNASSIGNED: Herein, the case of an 80-year-old male with a histologically confirmed diagnosis of ABC involving the body of the left mandible was presented. The patient underwent partial mandiblectomy after confirmation of the diagnosis using orthopantomography, a computed tomography scan, and a tissue biopsy. The patient was free from pain after 1-year of follow-up, and the control orthopantomography showed no evidence of recurrence. This was followed by reconstruction of the healed part of the bone with titanium plates and a piece of bone from the lateral two-thirds of the left femur and thereafter he was cosmetically well.
    UNASSIGNED: Patients with ABCs present with expansile and radiolucent bone lesions, which may be associated with displacement and loss of teeth due to alveolar bone erosion. Complete excision of the lesions is mandatory for the prevention of recurrence and increased morbidity.
    UNASSIGNED: ABCs that involve the jaws are extremely rare and are more likely to pose a diagnostic challenge as they are more likely to be confused clinically with other expansile radiolucent bone lesions such as ameloblastoma, osteoblastoma, and giant cell tumor among many others. Also, those with extensive bone matrix formation may sometimes be confused histologically with other bone forming tumors including osteosarcoma. Recurrence is common but it can be avoided or minimized by complete resection of the lesion.
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  • 文章类型: Journal Article
    动脉瘤性骨囊肿(ABC)是一种良性的局部破坏性骨肿瘤,由多部位充满血液的囊性空间组成。最常见的受累部位是长骨的骨干和椎骨的后部元素。次要,ABC样变化可使多种其他良性和恶性原发性骨肿瘤复杂化,包括巨细胞瘤,纤维发育不良,和骨肉瘤.大约三分之二的初级ABC具有USP6基因的重排,在其他原发性骨肿瘤继发的ABC样变化中不存在(即,二级ABC)。骨的原发性ABC具有可变的但通常较高的局部复发率。本文概述了病理生理学,临床表现,放射学和病理学发现,治疗,和ABC的预后。
    Aneurysmal bone cyst (ABC) is a benign locally destructive bone neoplasm composed of multi-loculated blood-filled cystic spaces. The most common sites of involvement are the meta-diaphysis of the long bones and posterior elements of the vertebrae. Secondary, ABC-like changes can complicate a variety of other benign and malignant primary bone neoplasms, including giant cell tumor, fibrous dysplasia, and osteosarcoma. About two-third of primary ABCs have a rearrangement of the USP6 gene, which is not present in the ABC-like changes that occur secondary to other primary bone tumors (i.e., secondary ABC). Primary ABC of bone carries a variable but generally high rate of local recurrence. This paper provides an overview of the pathophysiology, clinical presentation, radiographic and pathologic findings, treatment, and prognosis of ABC.
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  • 文章类型: Case Reports
    动脉瘤性骨囊肿是良性骨性病变,含有由结缔组织壁隔开的充血腔。由于表现相似,临床上可能很难识别它们,成像,和其他病理组织学。具体来说,区分这些良性病变和恶性病变很重要,因为手术和医疗管理不同。我们介绍了一名21岁患者的下肢运动和感觉功能受损的情况。放射学检查结果与浸润性肿瘤有关,术中冰冻切片支持这一结论.然而,另一项组织学检查证实了动脉瘤样骨囊肿的诊断.病人做了全身切除术,椎板切除术,和后路脊柱融合术,此后不久恢复了运动和感觉功能。本报告详细介绍了考虑动脉瘤性骨囊肿在鉴别浸润性骨病变中的重要性。尽管它们是良性的,因为医疗和外科管理可能差异很大。
    Aneurysmal bone cysts are benign osseous lesions containing blood-filled cavities separated by walls of connective tissue. They can be difficult to identify clinically due to similarities in presentation, imaging, and histology with other pathologies. Specifically, it is important to distinguish these benign lesions from malignant processes, as both surgical and medical management differ. We present the case of a 21-year-old patient who presented with impaired motor and sensory function in his lower extremities. Radiologic findings were concerning for an invasive neoplasm, and the intraoperative frozen section supported this conclusion. However, an additional histological investigation was confirmatory for a diagnosis of an aneurysmal bone cyst. The patient underwent corpectomy, laminectomy, and a posterior spinal fusion, and regained motor and sensory function shortly thereafter. This report details the importance of considering aneurysmal bone cysts in the differential of infiltrative bone lesions, despite their benign nature, as medical and surgical management can vary greatly.
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  • 文章类型: Case Reports
    动脉瘤性骨囊肿(ABCs)是非肿瘤性原发性骨肿瘤,通常在生命的前20年涉及长骨和椎骨。由于ABC的快速膨胀性质和破坏相邻正常骨的能力,因此需要及时诊断和干预。ABCs很少影响肋骨。我们报告了一例51岁女性,表现为慢性干咳和右上背部疼痛。胸部X光和计算机断层扫描显示有膨胀,影响第三右肋骨后部的溶解性肿块。使用后外侧切除了第三根右肋骨,Shaw-Paulson方法.切除肿块的组织病理学证实了ABC的诊断。没有术中或围手术期并发症,随访X线片正常。
    Aneurysmal bone cysts (ABCs) are non-neoplastic primary bone tumors, typically involving the long bones and vertebrae in the first 2 decades of life. ABCs require prompt diagnosis and intervention due to their rapidly expansile nature and ability to destroy the adjacent normal bone. ABCs rarely affect the rib. We report a case of a 51-year-old female presenting with chronic dry cough and right upper back pain. A chest X-ray and computed tomography scan revealed an expansile, lytic mass affecting the posterior aspect of the third right rib. The third right rib was resected using a posterolateral, Shaw-Paulson approach. Histopathology of the resected mass confirmed the diagnosis of ABC. There were no intra- or perioperative complications, and follow-up X-ray was normal.
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