对后半规管裂开(PSCD)进行系统回顾,并介绍一系列有或没有经典第三窗口症状的PSCD患者。
PubMed,Scopus,和Cochrane图书馆从成立到2019年4月。在一个多学科中看到的五个患者的病例系列,前庭聚焦,神经科诊所.
纳入标准:症状学的PSCD研究,诊断测试,放射学,和组织病理学。
非英语文章,reviews,信件,动物研究。
根据牛津循证医学中心标准和漏斗图通过Stern和Egger方法评估质量。
发现了两百五个研究,共纳入58项研究。在47名患者中,声音诱发的眩晕,混合性听力损失,耳鸣是最常见的症状。使用8项放射学和组织病理学研究对比例进行的荟萃分析显示,成人耳朵的发病率为0.38%[95%CI0.08,0.89],成人患者的发病率为2.16%[0.64,4.54]。儿科患者的发病率为1.3%至43%。颈静脉球异常很常见。在我们的案例系列中,五名患者中有四名没有第三窗口症状,其中一人患有声音和压力诱发的眩晕。这些患者的听力损失无法挽救。
PSCD是一种罕见的现象,最常见于第三窗口型症状。然而,PSCD也可能表现为与第三窗口症状学不一致的头晕和听力损失。人们应该意识到这些患者的听力恢复可能较差的预后。
To conduct a systematic
review of posterior semicircular canal dehiscence (PSCD) and to present a series of patients with PSCD with and without classic third-window symptoms.
PubMed, Scopus, and the Cochrane Library from inception until April 2019. Case series of five patients seen in a multidisciplinary, vestibular-focused, neurotology clinic.
Inclusion criteria: PSCD studies of symptomatology, diagnostic testing, radiology, and histopathology.
non-English articles, reviews, letters, animal studies.
Quality evaluated according to Oxford Center for Evidence-Based Medicine criteria and funnel plot via the Stern and Egger method.
Two hundred five studies were found, and 58 studies were included. In 47 total patients, sound-induced vertigo, mixed hearing loss, and tinnitus were the most common presenting symptom. A meta-analysis of proportions using eight radiological and histopathological studies revealed an incidence of 0.38% adult ears [95% CI 0.08, 0.89] and 2.16% of adult patients [0.64, 4.54]. The incidence in pediatric patients ranged from 1.3 to 43%. Jugular bulb abnormalities were common. In our case series, four of five patients presented without third-window symptoms, while one had sound- and pressure-induced vertigo. Hearing loss in these patients was not salvageable.
PSCD is a rare phenomenon most commonly presenting with third-window type symptoms. However, PSCD might also present with dizziness and hearing loss inconsistent with third-window symptomatology. One should be conscious of potentially poorer prognosis for hearing recovery in these patients.