据报道,数字眼部按摩可暂时降低眼内压(IOP)。这可能与房水流出增加有关;然而,机制尚不清楚。使用眼前段光学相干断层扫描,可以对Schlemm管(SC)和小梁网(TM)进行成像和测量。这里,66名健康成年人在他们的右眼中接受了10分钟的数字眼部按摩。在眼部按摩之前和之后测量SC和TM的IOP和尺寸。所有受试者均显示眼压从基线时的15.7±2.5mmHg降低至即刻的9.6±2.2mmHg,眼部按摩后5分钟的中位数为11.6mmHg(弗里德曼试验,p<0.001)。SC面积有显著变化(基线时中位数为10,063.5μm2,眼部按摩后中位数为10,151.0μm2,Wilcoxon试验,p=0.02),和TM厚度(眼部按摩后基线中位数为149.8μm至144.6±25.3μm,Wilcoxon试验,p=0.036)。三分之一的受试者表现出SC区域塌陷(-2至-52%),而三分之二的人显示SC面积扩大(2%至168%)。SC直径无明显变化(270.4±84.1μm与276.5±68.7μm,配对t检验,p=0.499),和TM宽度(733.3±110.1μmvs.733.5±111.6μm,配对t检验,p=0.988)。具有较高基线IOP的眼睛显示更大的IOP降低(皮尔逊相关系数r=-0.521,p<0.001)。基线时SC面积较小的眼睛显示出更大的SC面积扩张(Pearson相关系数=-0.389,p<0.001)。在SC面积扩张较大的眼睛中出现更大的IOP降低(Pearson相关系数r=-0.306,p=0.01)。眼压变化与TM厚度变化之间的相关性不显著(Spearman’sρ=0.015,p=0.902)。简单的数字眼部按摩是降低IOP值的有效方法,SC面积的变化与IOP变化显着相关。
Digital ocular massage has been reported to temporarily lower intraocular pressure (IOP). This could be related to an enhanced aqueous humor outflow; however, the mechanism is not clearly understood. Using anterior segment optical coherence tomography, the Schlemm\'s canal (SC) and trabecular meshwork (TM) can be imaged and measured. Here, 66 healthy adults underwent digital ocular massage for 10 min in their right eyes. The IOP and dimensions of the SC and TM were measured before and after ocular massage. All subjects demonstrated IOP reduction from 15.7 ± 2.5 mmHg at baseline to 9.6 ± 2.2 mmHg immediately after, and median of 11.6 mmHg 5-min after ocular massage (Friedman\'s test, p < 0.001). There was significant change in SC area (median 10,063.5 μm2 at baseline to median 10,151.0 μm2 after ocular massage, Wilcoxon test, p = 0.02), and TM thickness (median 149.8 μm at baseline to 144.6 ± 25.3 μm after ocular massage, Wilcoxon test, p = 0.036). One-third of the subjects demonstrated collapse of the SC area (-2 to -52%), while two-thirds showed expansion of the SC area (2 to 168%). There were no significant changes in SC diameter (270.4 ± 84.1 μm vs. 276.5 ± 68.7 μm, paired t-test, p = 0.499), and TM width (733.3 ± 110.1 μm vs. 733.5 ± 111.6 μm, paired t-test, p = 0.988). Eyes with a higher baseline IOP demonstrated a greater IOP reduction (Pearson correlation coefficient r = -0.521, p < 0.001). Eyes with smaller SC area at baseline showed greater SC area expansion (Pearson correlation coefficient = -0.389, p < 0.001). Greater IOP reduction appeared in eyes with greater SC area expansion (Pearson correlation coefficient r = -0.306, p = 0.01). Association between change in IOP and change in TM thickness was not significant (Spearman\'s ρ = 0.015, p = 0.902). Simple digital ocular massage is an effective method to lower IOP values, and change in the SC area was significantly associated with IOP changes.