Abstract：
OBJECTIVE: To evaluate the effect of uneventful cataract surgery on Schlemm\'s canal (SC) and the trabecular meshwork (TM) in cases with pseudoexfoliation (PX).
METHODS: In this prospective study, 37 PX and 37 normal eyes, who underwent cataract surgery, were included. The PX group was further divided into two subgroups: PX syndrome (PXS) and PX glaucoma (PXG). Preoperative complete ophthalmologic examination, anterior segment (AS) imaging using a Scheimpflug camera, and measurements of SC length and area and TM thickness and length using AS optical coherence tomography (AS-OCT) were performed in all cases. All measurements were repeated at the first and third months after surgery.
RESULTS: Preoperative intraocular pressure (IOP), AS parameters, SC, and TM values showed no significant differences between the groups (p > 0.05). After surgery, there was a significant increase in AS parameter values and a significant decrease in IOP values in both the PX and control groups (p < 0.05). The nasal and temporal SC area showed a significant increase in the PX group after surgery (p = 0.007, p = 0.003, respectively). In the subgroup analysis, the only significant change in the nasal and temporal SC area was in the PXS group (p = 0.006, p = 0.003, respectively).
CONCLUSIONS: Cataract surgery resulted in an increase in the SC area in patients with PXS. This increase may be due to multiple mechanisms including the IOP-lowering effect of cataract removal, change in AS, and removal of intraocular PX material after surgery.
METHODS: In this prospective study, 37 PX and 37 normal eyes, who underwent cataract surgery, were included. The PX group was further divided into two subgroups: PX syndrome (PXS) and PX glaucoma (PXG). Preoperative complete ophthalmologic examination, anterior segment (AS) imaging using a Scheimpflug camera, and measurements of SC length and area and TM thickness and length using AS optical coherence tomography (AS-OCT) were performed in all cases. All measurements were repeated at the first and third months after surgery.
RESULTS: Preoperative intraocular pressure (IOP), AS parameters, SC, and TM values showed no significant differences between the groups (p > 0.05). After surgery, there was a significant increase in AS parameter values and a significant decrease in IOP values in both the PX and control groups (p < 0.05). The nasal and temporal SC area showed a significant increase in the PX group after surgery (p = 0.007, p = 0.003, respectively). In the subgroup analysis, the only significant change in the nasal and temporal SC area was in the PXS group (p = 0.006, p = 0.003, respectively).
CONCLUSIONS: Cataract surgery resulted in an increase in the SC area in patients with PXS. This increase may be due to multiple mechanisms including the IOP-lowering effect of cataract removal, change in AS, and removal of intraocular PX material after surgery.
摘要：
目的：评估假性剥脱（PX）患者的顺利白内障手术对Schlemm管（SC）和小梁网（TM）的影响。
方法：在这项前瞻性研究中，37只PX和37只正常眼睛，接受白内障手术的人，包括在内。将PX组进一步分为两个亚组：PX综合征（PXS）和PX青光眼（PXG）。术前全面眼科检查，使用Scheimpflug相机进行眼前段（AS）成像，在所有情况下，使用AS光学相干断层扫描（AS-OCT）进行SC长度和面积以及TM厚度和长度的测量。在手术后的第一个月和第三个月重复所有测量。
结果：术前眼压（IOP），AS参数,SC,和TM值在各组间无显著差异(p>0.05)。手术后,在PX组和对照组中,AS参数值显著升高,IOP值显著降低(p<0.05).术后PX组鼻腔和颞侧SC面积均有显著增加(分别为p=0.007,p=0.003)。在亚组分析中，鼻腔和颞部SC面积的唯一显著变化是PXS组(分别为p=0.006,p=0.003).
结论：白内障手术导致PXS患者SC面积增加。这种增加可能是由于多种机制，包括白内障摘除的降低IOP的作用，AS的变化，手术后去除眼内PX材料。
方法：在这项前瞻性研究中，37只PX和37只正常眼睛，接受白内障手术的人，包括在内。将PX组进一步分为两个亚组：PX综合征（PXS）和PX青光眼（PXG）。术前全面眼科检查，使用Scheimpflug相机进行眼前段（AS）成像，在所有情况下，使用AS光学相干断层扫描（AS-OCT）进行SC长度和面积以及TM厚度和长度的测量。在手术后的第一个月和第三个月重复所有测量。
结果：术前眼压（IOP），AS参数,SC,和TM值在各组间无显著差异(p>0.05)。手术后,在PX组和对照组中,AS参数值显著升高,IOP值显著降低(p<0.05).术后PX组鼻腔和颞侧SC面积均有显著增加(分别为p=0.007,p=0.003)。在亚组分析中，鼻腔和颞部SC面积的唯一显著变化是PXS组(分别为p=0.006,p=0.003).
结论：白内障手术导致PXS患者SC面积增加。这种增加可能是由于多种机制，包括白内障摘除的降低IOP的作用，AS的变化，手术后去除眼内PX材料。
