过渡金属二硫属化合物(TMDC)由于其优异的物理和化学性质而被广泛用于生物传感应用。由于生物材料靶标的特性,生物传感器目前面临的最大挑战是如何提高灵敏度和稳定性。已经使用了许多材料来增强目标信号。其中,TMDC在增强生物传感信号方面表现出优异的性能,因为它们具有金属和半导电的电学功能,可调带隙,大的比表面积等。这里,本文综述了基于TMDC的生物传感器的不同功能化方法和研究进展。用于生物传感器制造的TMDC的修饰方法主要包括两种策略:非共价和共价相互作用。文章总结了不同修饰策略的优缺点及其对生物传感性能的影响。作者提出了TMDC在生物传感器应用中需要解决的挑战和问题。最后,该综述表达了基于TMDC的生物传感器在未来的积极应用前景。
Transition metal dichalcogenides (TMDCs) are widely used in biosensing applications due to their excellent physical and chemical properties. Due to the properties of biomaterial targets, the biggest challenge that biosensors face now is how to improve the sensitivity and stability. A lot of materials had been used to enhance the target signal. Among them, TMDCs show excellent performance in enhancing biosensing signals because of their metallic and semi-conducting electrical capabilities, tunable band gap, large specific surface area and so on. Here, we
review different functionalization methods and research progress of TMDCs-based biosensors. The modification methods of TMDCs for biosensor fabrication mainly include two strategies: non-covalent and covalent interaction. The article summarizes the advantages and disadvantages of different modification strategies and their effects on biosensing performance. The authors present the challenges and issues that TMDCs need to be addressed in biosensor applications. Finally, the
review expresses the positive application prospects of TMDCs-based biosensors in the future.