未经批准:对安全有效的植物制剂的需求,以增加肌肉质量,力量,运动员和普通人群的耐力正在增加。药用植物来源的营养补充剂对健康的关注最小。
未经批准:这是随机的,双盲,安慰剂对照研究的目的是评估专有的体格力潜力,Sphaeranthusindicus花头和芒果茎皮提取物的标准化配方(LI12542F6)。
UNASSIGNED:40名18-40岁的男性参与者被分配接受安慰剂(n=20)或650mg/天的LI12542F6(n=20),持续56天。所有参与者在干预期间进行了一组固定的阻力练习。主要终点是从基线肌肉力量的变化,通过一次重复最大(1-RM)工作台和腿部压力机进行评估,和握力。次要端点包括电缆下拉重复,是时候在跑步机上精疲力尽了,中上臂圆周(MUAC),使用双能X射线吸收法(DEXA)的身体成分,以及血清中游离的睾酮和皮质醇水平.
UNASSIGNED:56天补充LI12542F6可显着改善基线卧床(P<0.0001),腿部按压(P<0.0001),握力(P<0.0006),重复次数(P<0.0001),和耗尽时间(P<0.0008),与安慰剂相比。审判后,LI12542F6组也显示MUAC显著增加,体成分和血清激素水平改善.参与者的血液学,临床化学,生命体征均在正常范围内。没有观察到不良事件。
UNASSIGNED:这项研究表明,补充LI12542F6可显着增加健康男性的肌肉力量和大小,并改善耐力。此外,参与者对LI12542F6的耐受性良好。
UNASSIGNED: The demand for safe and efficacious botanical formulations to increase muscle mass, strength, and stamina is increasing among athletes and the general population. The nutraceutical supplements of medicinal plant origin exert minimal health concern.
UNASSIGNED: This randomized, double-blind, placebo-controlled
study was aimed to evaluate the ergogenic potential of a proprietary, standardized formulation (LI12542F6) of Sphaeranthus indicus flower head and Mangifera indica stem bark extracts.
UNASSIGNED: Forty male participants 18-40 years of age were assigned to receive either a placebo (n = 20) or 650 mg/day LI12542F6 (n = 20) for 56 days. All participants performed a fixed set of resistance exercises during the intervention. The primary endpoint was the change from baseline muscle strength, assessed by one-repetition maximum (1-RM) bench and leg presses, and handgrip strength. The secondary endpoints included cable pull-down repetitions, time to exhaustion on a treadmill, mid-upper arm circumference (MUAC), body composition using dual-energy x-ray absorptiometry (DEXA), and free testosterone and cortisol levels in serum.
UNASSIGNED: Fifty-six days supplementation of LI12542F6 significantly improved baseline bench press (P < 0.0001), leg press (P < 0.0001), handgrip strength (P < 0.0006), number of repetitions (P < 0.0001), and time to exhaustion (P < 0.0008), compared to placebo. Post-
trial, the LI12542F6 group also showed significantly increased MUAC and improved body composition and serum hormone levels. The participants\' hematology, clinical chemistry, and vital signs were within the normal range. No adverse events were observed.
UNASSIGNED: This
study demonstrates that LI12542F6 supplementation significantly increases muscle strength and size and improves endurance in healthy men. Also, LI12542F6 is well-tolerated by the participants.