PDF(Pubmed)
Abstract：
Maintenance of the quality and hygiene of maxillofacial prosthesis allows to maintain the health of the residual tissues. Sampling of the maxillofacial prostheses has relieved presence of microbial colonization on silicone surfaces. Cleaning procedures of maxillofacial silicones are done using mechanical means or using adjunctive with chemical means. Cleaning with a 2-4% chlorhexidine gluconate spray or dipping in solution for a minute and then washing under running water can sufficiently condition to reduce the amount of bacterial contamination. Due to rising microorganism resistance and fewer adverse effects, phytoextracts appear to be a viable option. Additionally, the use of excipients derived from plants is provides new opportunities for the pharmaceutical industry into the creation of innovative pharmaceutical products that are sustainable.
UNASSIGNED: To evaluate and compare the leaf extracts of Mangifera indica (M.indica), Anacardium occidentale(A.occidentale) and 0.2% chlorhexidine gluconate (CHX) on disinfection of maxillofacial silicone material surface contaminated with Staphylococcus aureus (S.aureus) and Candida albicans (C.albicans).
UNASSIGNED: Of the 150 maxillofacial silicone elastomer silicone samples, 75 samples were contaminated with S. aureus and 75 with C.albicans. The contaminated disc was rolled on blood agar and pre-disinfection Colony Forming Units (CFU) were evaluated followed by subjecting the discs to disinfection protocols. The contaminated discs with S. aureus and C.albicans were disinfected using M.indica leaf extracts, A.occidentale leaf extracts and 0.2% CHX for 10 min. Post-disinfection CFUs were evaluated by rolling the disc on blood agar. The results were tabulated and analysed using dependent t-test, one-way ANOVA and Tukeys multiple posthoc procedure.
UNASSIGNED: Pair-wise comparison of pre-and post-disinfection log CFU counts of S.aureus gave a statistical significance between 0.2% CHX and and M.indica leaf extract. No statistically significant results were found between 0.2% CHX and A.occidentale. Pair wise comparison of the log CFU from pre-disinfection to post-disinfection of C.albicans gave a statistical significance between all the three groups.
UNASSIGNED: In the present study A.occidentale leaf extract and M.indica leaf extract have shown significant reduction in CFU of both the organisms. 0.2% CHX showed the most CFU reduction post disinfection of maxillofacial silicone material surface contaminated S.aureus and C.albicans followed by A.occidentale leaf extracts and M.indica leaf extracts. Given the limitations of the current research, A.occidentale leaf extract and M.indica leaf extract can be used as an alternative for disinfection of maxillofacial silicone prosthesis.
UNASSIGNED: To evaluate and compare the leaf extracts of Mangifera indica (M.indica), Anacardium occidentale(A.occidentale) and 0.2% chlorhexidine gluconate (CHX) on disinfection of maxillofacial silicone material surface contaminated with Staphylococcus aureus (S.aureus) and Candida albicans (C.albicans).
UNASSIGNED: Of the 150 maxillofacial silicone elastomer silicone samples, 75 samples were contaminated with S. aureus and 75 with C.albicans. The contaminated disc was rolled on blood agar and pre-disinfection Colony Forming Units (CFU) were evaluated followed by subjecting the discs to disinfection protocols. The contaminated discs with S. aureus and C.albicans were disinfected using M.indica leaf extracts, A.occidentale leaf extracts and 0.2% CHX for 10 min. Post-disinfection CFUs were evaluated by rolling the disc on blood agar. The results were tabulated and analysed using dependent t-test, one-way ANOVA and Tukeys multiple posthoc procedure.
UNASSIGNED: Pair-wise comparison of pre-and post-disinfection log CFU counts of S.aureus gave a statistical significance between 0.2% CHX and and M.indica leaf extract. No statistically significant results were found between 0.2% CHX and A.occidentale. Pair wise comparison of the log CFU from pre-disinfection to post-disinfection of C.albicans gave a statistical significance between all the three groups.
UNASSIGNED: In the present study A.occidentale leaf extract and M.indica leaf extract have shown significant reduction in CFU of both the organisms. 0.2% CHX showed the most CFU reduction post disinfection of maxillofacial silicone material surface contaminated S.aureus and C.albicans followed by A.occidentale leaf extracts and M.indica leaf extracts. Given the limitations of the current research, A.occidentale leaf extract and M.indica leaf extract can be used as an alternative for disinfection of maxillofacial silicone prosthesis.
摘要：
保持颌面部假体的质量和卫生可以保持残留组织的健康。对颌面假体进行采样可以减轻有机硅表面上微生物定植的存在。使用机械手段或使用化学手段辅助进行颌面有机硅的清洁程序。用2-4%葡萄糖酸氯己定喷雾或在溶液中浸渍一分钟,然后在流水下洗涤,可以充分地减少细菌污染的量。由于微生物耐药性上升，不良反应较少，植物提取物似乎是一个可行的选择。此外,使用来自植物的赋形剂为制药行业创造可持续的创新制药产品提供了新的机会。
■评估和比较芒果叶提取物(M.印度)，西药房室(A.occidentale）和0.2％葡萄糖酸氯己定（CHX）对被金黄色葡萄球菌污染的颌面部有机硅材料表面的消毒（S.金黄色葡萄球菌）和白色念珠菌（C.albicans).
■在150个颌面硅胶弹性体硅胶样品中，75个样品被金黄色葡萄球菌污染,75个样品被白色念珠菌污染。将污染的圆盘在血琼脂上滚动,并评估预消毒菌落形成单位(CFU),然后使圆盘经受消毒方案。使用M.indica叶提取物对金黄色葡萄球菌和白色念珠菌污染的圆盘进行消毒，A.occidentale叶提取物和0.2％CHX持续10分钟。通过在血琼脂上滚动圆盘来评估消毒后CFU。结果采用依赖t检验制表和分析，单向方差分析和Tukey多重后手术。
■金黄色葡萄球菌的消毒前和消毒后对数CFU计数的成对比较在0.2%CHX和M.indica叶提取物之间给出了统计学显著性。在0.2%CHX和A.occidental之间没有发现有统计学意义的结果。白色念珠菌从消毒前到消毒后的对数CFU的成对比较在所有三组之间给出了统计学显著性。
■在本研究中，西洋菊叶提取物和m.indica叶提取物显示两种生物的CFU均显着降低。0.2％CHX在消毒后对颌面部有机硅材料表面污染的金黄色葡萄球菌和白色念珠菌的CFU降低幅度最大，其次是西花念珠菌叶提取物和M.indica叶提取物。鉴于目前研究的局限性,occidentale叶提取物和M.indica叶提取物可用作颌面部硅胶假体消毒的替代品。
■评估和比较芒果叶提取物(M.印度)，西药房室(A.occidentale）和0.2％葡萄糖酸氯己定（CHX）对被金黄色葡萄球菌污染的颌面部有机硅材料表面的消毒（S.金黄色葡萄球菌）和白色念珠菌（C.albicans).
■在150个颌面硅胶弹性体硅胶样品中，75个样品被金黄色葡萄球菌污染,75个样品被白色念珠菌污染。将污染的圆盘在血琼脂上滚动,并评估预消毒菌落形成单位(CFU),然后使圆盘经受消毒方案。使用M.indica叶提取物对金黄色葡萄球菌和白色念珠菌污染的圆盘进行消毒，A.occidentale叶提取物和0.2％CHX持续10分钟。通过在血琼脂上滚动圆盘来评估消毒后CFU。结果采用依赖t检验制表和分析，单向方差分析和Tukey多重后手术。
■金黄色葡萄球菌的消毒前和消毒后对数CFU计数的成对比较在0.2%CHX和M.indica叶提取物之间给出了统计学显著性。在0.2%CHX和A.occidental之间没有发现有统计学意义的结果。白色念珠菌从消毒前到消毒后的对数CFU的成对比较在所有三组之间给出了统计学显著性。
■在本研究中，西洋菊叶提取物和m.indica叶提取物显示两种生物的CFU均显着降低。0.2％CHX在消毒后对颌面部有机硅材料表面污染的金黄色葡萄球菌和白色念珠菌的CFU降低幅度最大，其次是西花念珠菌叶提取物和M.indica叶提取物。鉴于目前研究的局限性,occidentale叶提取物和M.indica叶提取物可用作颌面部硅胶假体消毒的替代品。
