PDF(Pubmed)
Abstract：
BACKGROUND: Folk medicine is crucial to healthcare delivery in the underdeveloped countries. It is frequently used as a primary treatment option or as a complementary therapy for malaria. Malaria is a deadly disease which greatly threatens global public health, claiming incredible number of lives yearly. The study was aimed at documenting the medicinal plants used for malaria treatment in folk medicine in Kwara State, Nigeria.
METHODS: Ethnobotanical information was collected from selected consenting registered traditional medicine practitioners (TMPs) through oral face-to-face interviews using in-depth, semi-structured interview guide. The ethnobotanical data were analysed, and descriptive statistical methods were used to compile them.
RESULTS: Sixty-two indigenous medicinal plants, including 13 new plants, used for malaria treatment were identified in this study. The TMPs preferred decoction in aqueous solvent (34%) and steeping in decaffeinated soft drink (19%) for herbal preparations. Oral administration (74%) was the main route of administration, while leaves (40%) and stem barks (32%) were the most dominant plant parts used in herbal preparations. The most cited families were Fabaceae (15%) and Rutaceae (6%), while Mangifera indica (77.14%), Enantia chlorantha (65.71%), Alstonia boonei (57.14%) followed by Cymbopogon citratus (54.29%) were the most used plants. Besides, the antimalarial activities of many of the plants recorded and their isolated phytocompounds have been demonstrated. Furthermore, the conservation status of 4 identified plants were Vulnerable.
CONCLUSIONS: The study showed strong ethnobotanical knowledge shared by the TMPs in the State and provides preliminary information that could be explored for the discovery of more potent antimalarial compounds.
METHODS: Ethnobotanical information was collected from selected consenting registered traditional medicine practitioners (TMPs) through oral face-to-face interviews using in-depth, semi-structured interview guide. The ethnobotanical data were analysed, and descriptive statistical methods were used to compile them.
RESULTS: Sixty-two indigenous medicinal plants, including 13 new plants, used for malaria treatment were identified in this study. The TMPs preferred decoction in aqueous solvent (34%) and steeping in decaffeinated soft drink (19%) for herbal preparations. Oral administration (74%) was the main route of administration, while leaves (40%) and stem barks (32%) were the most dominant plant parts used in herbal preparations. The most cited families were Fabaceae (15%) and Rutaceae (6%), while Mangifera indica (77.14%), Enantia chlorantha (65.71%), Alstonia boonei (57.14%) followed by Cymbopogon citratus (54.29%) were the most used plants. Besides, the antimalarial activities of many of the plants recorded and their isolated phytocompounds have been demonstrated. Furthermore, the conservation status of 4 identified plants were Vulnerable.
CONCLUSIONS: The study showed strong ethnobotanical knowledge shared by the TMPs in the State and provides preliminary information that could be explored for the discovery of more potent antimalarial compounds.
摘要：
背景：民间医学对于不发达国家的医疗保健服务至关重要。它经常被用作疟疾的主要治疗选择或补充疗法。疟疾是一种致命的疾病，极大地威胁着全球公共卫生。每年都有令人难以置信的生命。该研究旨在记录夸拉州民间医学中用于治疗疟疾的药用植物，尼日利亚。
方法：通过口腔面对面访谈，从选定的同意注册的传统医学从业人员（TMP）中收集了民族植物学信息，半结构化面试指南。对民族植物学数据进行了分析，并采用描述性统计方法进行编制。
结果：62种本土药用植物，包括13个新工厂，在这项研究中确定用于疟疾治疗。TMPs首选在水性溶剂中的煎剂（34％）和在无咖啡因软饮料中的浸泡（19％）用于草药制剂。口服给药(74%)是主要的给药途径,而叶子（40％）和茎皮（32％）是草药制剂中使用的最主要的植物部分。被引用最多的是豆科(15%)和豆科(6%)，而印度芒果(77.14%)，天麻(65.71%),最常用的植物是鲍氏Alstonia（57.14％），其次是Cymboponcitratratus（54.29％）。此外,已证明许多记录的植物及其分离的植物化合物的抗疟活性。此外，4种确定的植物的保护状况是脆弱的。
结论：该研究表明，该州的TMPs具有很强的民族植物学知识，并提供了可以探索的初步信息，以发现更有效的抗疟化合物。
方法：通过口腔面对面访谈，从选定的同意注册的传统医学从业人员（TMP）中收集了民族植物学信息，半结构化面试指南。对民族植物学数据进行了分析，并采用描述性统计方法进行编制。
结果：62种本土药用植物，包括13个新工厂，在这项研究中确定用于疟疾治疗。TMPs首选在水性溶剂中的煎剂（34％）和在无咖啡因软饮料中的浸泡（19％）用于草药制剂。口服给药(74%)是主要的给药途径,而叶子（40％）和茎皮（32％）是草药制剂中使用的最主要的植物部分。被引用最多的是豆科(15%)和豆科(6%)，而印度芒果(77.14%)，天麻(65.71%),最常用的植物是鲍氏Alstonia（57.14％），其次是Cymboponcitratratus（54.29％）。此外,已证明许多记录的植物及其分离的植物化合物的抗疟活性。此外，4种确定的植物的保护状况是脆弱的。
结论：该研究表明，该州的TMPs具有很强的民族植物学知识，并提供了可以探索的初步信息，以发现更有效的抗疟化合物。
