Cosmeceuticals

化妆品
  • 文章类型: Journal Article
    背景:粗糙度,下垂,在接受LH-RH类似物联合他莫昔芬或芳香化酶抑制剂辅助手术后内分泌治疗的乳腺癌患者中,皮疹较为常见.局部使用视黄醇(维生素A)已被证明是有效的美容治疗。
    目的:使用基于3%视黄醇的高级视黄醇剥离制剂进行剥离,4%柠檬酸三乙酯,0.1%氨性粒细胞,没药醇,和1%的维生素E乙酸酯,在载体中的醇溶液已成功地用于改善患有光损伤的受试者和老年人群的皮肤外观。我们旨在验证其在辅助化疗期间的使用。
    方法:四名在乳腺癌术后辅助治疗期间出现皮肤问题的受试者在停止术后治疗后至少6周接受视黄醇剥皮治疗,作为一种低侵入性美容治疗,可在皮肤科和家中使用。
    结果:视黄醇皮有效,安全,和良好的耐受性,改善所有患者的皮肤亮度和紧致度,自4周后开始治疗。患者宣布对治疗和他们的皮肤外观感到满意,让他们对癌症康复感觉更好,也是。
    结论:这些初步观察表明,晚期视黄醇剥离制剂的使用可能会改善乳腺癌手术后辅助治疗引起皮肤损伤的女性的皮肤外观。
    BACKGROUND: Roughness, sagging, and skin rash are common in patients with breast cancer treated with LH-RH analog plus tamoxifen or aromatase inhibitors as adjuvant postsurgical endocrine therapy. The use of topical retinol (vitamin A) has shown to be an efficacious cosmetic treatment.
    OBJECTIVE: Peeling with an advanced retinol peel formulation based on 3% retinol, 4% triethyl citrate, 0.1% aminophil, bisabolol, and 1% vitamin E acetate, in a vehicle in an alcoholic solution has been successfully used to ameliorate skin appearance on subjects with photodamage and in the aged population. We aimed to verify its use during adjuvant chemotherapy.
    METHODS: Four subjects experiencing skin issues during postsurgical adjuvant therapy for their breast cancer received retinol peel at least 6 weeks after stopping their postsurgery therapy as a low invasive aesthetic medical treatment to be used both at the dermatology desk and at home.
    RESULTS: Retinol peel was effective, safe, and well-tolerated, improving skin brightness and firmness in all the patients, since 4 weeks after the beginning of the treatment. Patients declared to be satisfied with the treatment and their skin appearance letting them feel better for cancer recovery, too.
    CONCLUSIONS: These preliminary observations suggest that the use of an advanced retinol peel formulation might improve skin appearance in women experiencing skin damages caused by adjuvant therapy after breast cancer surgery.
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  • 文章类型: Journal Article
    背景:尽管防晒霜和保湿剂等化妆品通常被认为是安全的,如果使用不当,它们可能不太有效或有害。因此,药剂师对药妆品的认识在咨询成分和正确使用此类产品方面至关重要。
    目的:评估吉达社区药剂师对化妆品特别是防晒霜和保湿剂的认知水平,沙特阿拉伯。
    方法:这是一项针对吉达310名社区药剂师的横断面研究,沙特阿拉伯,在持续时间(2019年6月至11月)。
    结果:关于对防晒产品的认知程度,74%的参与者对防晒因子(SPF)有明确的了解。在防晒咨询和这些产品对药物诱导的光敏性的影响方面,参与者的平均知晓率为62%和55%,分别。然而,只有16%的参与者知道有效期.药剂师对保湿剂的有效期和正确使用/成分的平均知识为86%和58%,分别,而只有42%的参与者对使用保湿剂的说明做出了正确的反应。教育水平与获取化妆品知识的需求之间的交叉列表表明,大多数药剂师表示他们需要更多的化妆品知识。
    结论:大约53%的社区药剂师知道防晒部分,而62%的人有保湿知识。因此,建议更多的美容课程和讲习班,以提高意识水平。
    BACKGROUND: Although cosmetic products such as sunscreens and moisturizers are generally considered safe, they can be less effective or harmful if used improperly. Thus, pharmacist\'s awareness about cosmeceuticals is pivotal in counseling about the ingredients and the proper use of such products.
    OBJECTIVE: To evaluate the awareness level of community pharmacists regarding cosmetic products particularly sunscreens and moisturizers in Jeddah, Saudi Arabia.
    METHODS: This is a cross-sectional study conducted on 310 community pharmacists in Jeddah, Saudi Arabia, in the duration (June-November 2019).
    RESULTS: With respect to the level of awareness toward sunscreen products, 74% of the participants demonstrated a clear understanding of Sun Protection Factor (SPF). In terms of sunscreen counseling and the impact of these products on drug-induced photosensitivity, the average awareness of participants was 62% and 55%, respectively. However, only 16% of participants were aware of the expiry date. The average pharmacist\'s knowledge of the expiration date of the moisturizers and the proper use/ingredients was 86% and 58%, respectively, while only 42% of participants responded correctly to the instructions for application of moisturizers. Cross-tabulation between the level of education and the need to acquire knowledge about cosmetics has shown that the majority of pharmacists has indicated that they need more knowledge about cosmetics.
    CONCLUSIONS: Around 53% of community pharmacists are aware about the sunscreen part, while 62% have the knowledge about moisturizers. Hence, more cosmetic courses and workshops are recommended to raise level of awareness.
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  • 文章类型: Case Reports
    在患有糖尿病的个体中通常观察到许多皮肤损伤。糖尿病的常见皮肤表现是红斑,黄瘤病,xanthelasma,藻类和皮肤感染,如毛癣,念珠菌病,碳水化合物,皮肤癣菌病,等。糖尿病性皮肤病是糖尿病患者中最常见的皮肤病变。它通常见于50岁以上的男性。在低水平激光治疗(LLLT)中,以20Hz的频率和830nm的波长照射整个下肢9分钟,治疗分为四个部分。随着LLLT的继续会议,皮肤表现和神经病变状况大大改善。在第21天,发现皮肤颜色正常。此外,糖尿病周围神经病变的临床表现有显著改变.LLLT与特定运动可以促进2型糖尿病患者皮肤表现的愈合。它可以用作治疗糖尿病性皮肤病的有效治疗方式。
    Numerous skin lesions have been commonly observed in individuals with diabetes mellitus. The common skin manifestations of diabetes mellitus are erythrasma, xanthomatosis, xanthelasma, phycomycetes and cutaneous infections like furuncolosis, candidiasis, carbuncle, dermatophytosis, etc. Diabetic dermopathy is the most common skin lesion found in patients with diabetes. It is typically seen in men aged above 50 years. In low-level laser therapy (LLLT), the entire lower limb was illuminated with the frequency of 20 Hz and wavelength of 830 nm for 9 min, and the treatment was divided into four parts. With the continued sessions of LLLT, the skin manifestations and neuropathy conditions improved drastically. On the 21st day, the skin colour was found to be normal. Also, there were significant changes in clinical findings for diabetic peripheral neuropathy. LLLT with specific exercises can promote healing of skin manifestations in individuals with type 2 diabetes mellitus. It can be used as an effective treatment modality for treating diabetic dermopathy.
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