Cosmeceuticals

化妆品
  • 文章类型: Journal Article
    皮肤毒性在接受癌症治疗的患者中非常常见,并且发现所有类型的癌症治疗干预措施都会发生(细胞毒性化疗,靶向治疗,免疫疗法,和放射治疗)。Further,皮肤毒性可导致某些患者中断甚至停止抗癌治疗,转化为次优结果。皮肤化妆品(或药妆品)-定义为包含皮肤病学活性成分(超出赋形剂作用)的护肤溶液,可直接改善各种皮肤状况的症状-越来越多地用于癌症护理中以预防和管理皮肤毒性。这些产品中的活性成分在皮肤中具有可测量的生物作用;它们通常改善皮肤完整性(屏障功能/水合作用和其他因素),同时缓解皮肤症状。法语国家协会(AFSOS)和跨国癌症支持协会(MASCC)合作,选择了一个多学科的医疗保健专业人员小组参与癌症和皮肤毒性患者的管理。该小组审查了现有文献,并通过在线会议和交流创建了管理这些毒性的建议摘要。在本出版物中,该小组(1)回顾了肿瘤药物的新皮肤毒性,(2)评价了皮肤化妆品在改善患者预后和减少癌症治疗中断方面的作用.我们为所有肿瘤患者的皮肤护理的开始和选择提供一般建议,以及在特定类型的皮肤毒性中使用皮肤化妆品时应考虑的因素的建议。
    Skin toxicities are very common in patients undergoing cancer treatment and have been found to occur with all types of cancer therapeutic interventions (cytotoxic chemotherapy, targeted therapies, immunotherapy, and radiotherapy). Further, skin toxicities can lead to interruption or even discontinuation of anticancer treatment in some patients, translating to suboptimal outcomes. Dermocosmetics (or cosmeceuticals)-defined as skincare solutions incorporating dermatologically active ingredients (beyond vehicle effects) that directly improve symptoms of various skin conditions-are increasingly being used in cancer care to prevent and manage skin toxicities. The active ingredients in these products have a measurable biological action in skin; they typically improve skin integrity (barrier function/hydration and other factors) while relieving skin symptoms. The Association Francophone des Soins Oncologiques de Support (AFSOS) and Multinational Association of Supportive Care in Cancer (MASCC) partnered to select a multidisciplinary group of healthcare professionals involved in the management of patients with cancer and skin toxicities. The group reviewed existing literature and created a summary of recommendations for managing these toxicities through online meetings and communication. In this publication, the group (1) reviews new skin toxicities seen with oncology drugs and (2) evaluates the role of dermocosmetics in improving patient outcomes and minimizing cancer treatment interruptions. We provide general recommendations for initiation and selection of skin care in all oncology patients as well as recommendations for what factors should be considered when using dermocosmetics in specific types of skin toxicities.
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    文章类型: Journal Article
    由于新加坡的多种族患者人群具有不同的皮肤类型,临床医生经常发现患者痤疮的治疗具有挑战性.作者制定了这些指南,以提供有关个性化痤疮治疗的全面建议,并为所有治疗亚裔患者的医生提供参考指南。突出了新加坡痤疮的独特特征。我们解决饮食等问题,特殊人口需求,和好处,副作用,风险,和目前可用的痤疮治疗的成本效益。这些治疗指南概述了诊断的建议,分级,以及对儿童的治疗,青少年,和不同严重程度的痤疮的成年人,并包括有关药妆使用和疤痕管理的建议。
    Due to the multiethnic patient population with varying skin types in Singapore, clinicians often find the management of acne in their patients to be challenging. The authors developed these guidelines to provide comprehensive advice on individualized acne treatment and to provide a reference guide for all doctors who treat patients of Asian descent. Unique features of acne in Singapore are highlighted. We address concerns such as diet, special population needs, and the benefits, side effects, risks, and cost-effectiveness of currently available acne treatments. These treatment guidelines outline recommendations for the diagnosis, grading, and treatment of children, adolescents, and adults with acne of varying severity, and include advice pertaining to the use of cosmeceuticals and management of scars.
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  • 文章类型: Consensus Development Conference
    BACKGROUND: Rosacea is currently treated according to subtypes. As this does not adequately address the spectrum of clinical presentation (phenotypes), it has implications for patient management. The ROSacea COnsensus panel was established to address this issue.
    OBJECTIVE: To incorporate current best treatment evidence with clinical experience from an international expert panel and establish consensus to improve outcomes for patients with rosacea.
    METHODS: Seventeen dermatologists and three ophthalmologists reached consensus on critical aspects of rosacea treatment and management using a modified Delphi approach. The panel voted on statements using the responses \'strongly disagree\', \'disagree\', \'agree\' or \'strongly agree\'. Consensus was defined as ≥ 75% \'agree\' or \'strongly agree\'. All voting was electronic and blinded.
    RESULTS: The panel agreed on phenotype-based treatments for signs and symptoms presenting in individuals with rosacea. First-line treatments were identified for individual major features of transient and persistent erythema, inflammatory papules/pustules, telangiectasia and phyma, underpinned by general skincare measures. Multiple features in an individual patient can be simultaneously treated with multiple agents. If treatment is inadequate given appropriate duration, another first-line option or the addition of another first-line agent should be considered. Maintenance treatment depends on treatment modality and patient preferences. Ophthalmological referral for all but the mildest ocular features should be considered. Lid hygiene and artificial tears in addition to medications are used to treat ocular rosacea.
    CONCLUSIONS: Rosacea diagnosis and treatment should be based on clinical presentation. Consensus was achieved to support this approach for rosacea treatment strategies.
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  • 文章类型: Journal Article
    Atopic dermatitis (AD) is a condition frequently encountered in medical practices across the country. More than 60% of children with AD are at risk to develop allergic rhinitis or asthma (the atopic march). Patients with AD have a unique predisposition to colonization or infection by Staphylococcus aureus. Treatments for AD need to rapidly control symptoms of the disease, improve quality of life and prevent exacerbations. Given the chronic and relapsing nature of the disease, therapies need to encourage good compliance and be well tolerated.
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