■本研究旨在综合接受角膜塑形术治疗的近视儿童在不同随访间隔下观察到的中央凹下脉络膜厚度(SFCT)的变化。
■从PubMed、EMBASE,WebofScience,科克伦图书馆检索期从这些数据库的开始延伸到2023年11月。选择基线和治疗后SFCT的平均值和标准偏差(SD)作为分析和计算的结果。
■共有8篇涉及478只眼睛的文章符合纳入标准。在1个月,3个月,和6个月的间隔,SFCT显着增加16.74μm(95%CI:8.66,24.82;p<0.0001),13.41μm(95%CI:4.36,22.45;p=0.004),和17.57μm(95%CI:8.41,26.73;p=0.0002),分别。此外,与使用单眼眼镜(SVL)的儿童相比,使用角膜塑形镜治疗的儿童的SFCT改变明显更厚(WMD=13.50,95%CI:11.69,15.13;p<0.0001).
■接受角膜塑形术治疗的近视儿童在1个月时SFCT明显增加,3个月,和6个月。此外,与使用SVL的儿童相比,接受角膜塑形术的患者表现出更明显的SFCT增厚。
UNASSIGNED: This study aimed to synthesize the variations in subfoveal choroidal thickness (SFCT) observed at different follow-up intervals in myopic children undergoing orthokeratology treatment.
UNASSIGNED: Relevant articles were systematically retrieved from databases such as PubMed, EMBASE, Web of Science, and Cochrane Library. The retrieval period extended from the inception of these databases to November 2023. Means and standard deviations (SD) of baseline and post-treatment SFCT were selected as the results for analysis and calculation.
UNASSIGNED: A total of eight articles involving 478 eyes fulfilled the inclusion criteria. At 1 month, 3 months, and 6 months intervals, the SFCT demonstrated significant increases by 16.74 μm (95% CI: 8.66, 24.82; p < 0.0001), 13.41 μm (95% CI: 4.36, 22.45; p = 0.004), and 17.57 μm (95% CI: 8.41, 26.73; p = 0.0002), respectively. Besides, children treated with orthokeratology exhibited a notably thicker change of SFCT in comparison with children with single-vision spectacles (SVL) (WMD = 13.50, 95% CI: 11.69, 15.13; p < 0.0001).
UNASSIGNED: Myopic children undergoing orthokeratology treatment experience a discernible increase in SFCT at 1 month, 3 months, and 6 months. Furthermore, compared to children utilizing SVL, those undergoing orthokeratology manifest a more pronounced thickening of SFCT.