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Abstract：
Myopia is a common refractive error that affects a large proportion of the population. Recent studies have revealed that alterations in choroidal thickness (ChT) and choroidal blood flow (ChBF) play important roles in the progression of myopia. Reduced ChBF could affect scleral cellular matrix remodeling, which leads to axial elongation and further myopia progression. As ChT and ChBF could be used as potential biomarkers for the progression of myopia, several recent myopia treatments have targeted alterations in ChT and ChBF. Our review provides a comprehensive overview of the recent literature review on the relationship between ChBF and myopia. We also highlight the importance of ChT and ChBF in the progression of myopia and the potential of ChT as an important biomarker for myopia progression. This summary has significant implications for the development of novel strategies for preventing and treating myopia.
摘要：
近视是一种常见的屈光不正，影响很大比例的人群。最近的研究表明，脉络膜厚度（ChT）和脉络膜血流（ChBF）的变化在近视的进展中起重要作用。ChBF降低可影响巩膜细胞基质重塑，这导致轴向伸长和进一步的近视进展。由于ChT和ChBF可以作为近视进展的潜在生物标志物，最近的几种近视治疗方法有针对性地改变了ChT和ChBF。我们的综述提供了有关ChBF与近视之间关系的最新文献综述的全面概述。我们还强调了ChT和ChBF在近视进展中的重要性以及ChT作为近视进展的重要生物标志物的潜力。该总结对于预防和治疗近视的新策略的开发具有重要意义。
