目的:探讨经皮球囊压迫联合卡马西平治疗三叉神经痛的疗效。
方法:收集我院1月收治的126例TN患者的临床资料,2021年1月,2022年进行回顾性分析。所有患者均在我院接受了经皮球囊压迫术。将患者分为对照组和观察组,根据手术后是否继续服用卡马西平。患者的一般人口统计学数据,比如性别,年龄,家庭收入,教育水平,疼痛部位,患病的神经,病程,收集疼痛的持续时间。采用倾向评分匹配法平衡两组基线资料,和生活质量,治疗效果,匹配后比较两组并发症。
结果:治疗后,观察组总有效率(95.00%)高于对照组(70.00%)(p<0.05)。治疗前,两组患者生活质量各维度评分差异无统计学意义(p>0.05)。治疗后,观察组生活质量各维度得分均高于对照组。治疗后,观察组并发症发生率(7.50%)低于对照组(30.00%)(p<0.05)。
结论:经皮球囊压迫术联合卡马西平治疗可有效提高患者的生活质量,减少并发症的发生。这些结果可以改善TN的临床管理。
OBJECTIVE: To investigate the effect of percutaneous balloon compression combined with
carbamazepine on patients with Trigeminal Neuralgia (TN).
METHODS: The clinical data of 126 patients with TN admitted to our hospital from January, 2021 to January, 2022 were retrospectively analyzed. All patients underwent percutaneous balloon compression in our hospital. The patients were divided into a control group and an observation group, according to whether they continued to take
carbamazepine after surgery. The general demographic data of patients, such as gender, age, family income, education level, pain site, diseased nerve, course of disease, and duration of pain were collected. Propensity score matching was used to balance the baseline data of the two groups, and the quality of life, treatment effect, and complications of the two groups were compared after matching.
RESULTS: After treatment, the total effective rate of the observation group (95.00%) was higher than that of the control group (70.00%) (p < 0.05). Before treatment, there were no significant differences in the scores for quality of life dimensions between the two groups (p > 0.05). After treatment, the scores for each quality of life dimension in the observation group were higher than those in the control group. After treatment, the incidence of complications in the observation group (7.50%) was lower than that in the control group (30.00%) (p < 0.05).
CONCLUSIONS: Percutaneous balloon compression combined with
carbamazepine can effectively enhance the treatment of patients by improving their quality of life and reducing the occurrence of complications. These results can improve the clinical management of TN.