Body Temperature Regulation

体温调节
  • 文章类型: Journal Article
    一些国际联合会(IFs)采用特定的政策来保护运动员的健康免受高温的危害。大多数政策都依赖于诸如湿球温度(WBGT)之类的热指标的测量来估计与热有关的疾病的风险。这篇评论总结了2024年巴黎奥运会包括的45项运动中的32项IF实施的政策。它提供了场地类型的详细信息,测量参数,使用的热指数,测量程序,缓解策略,并指定该策略是建议还是要求。此外,提出了对运动热应激风险的分类。在被确定为高的15项运动中,非常高或极端的风险,一个人没有热力政策,三个没有指定任何参数测量,一个依赖于水温,两个关于空气温度和相对湿度,WBGT上有7个(现场测量6个,估计1个),热应力指数上有1个。然而,目前在体育运动中使用的指数是为士兵或工人制定的,可能无法充分反映运动员承受的热压力。值得注意的是,他们不考虑运动员的高代谢产热和他们的适应水平。是的,因此,值得列出IFs用于量化热应力风险的热指数的相关性,在不久的将来,制定适合运动员特定需求的指数。
    Several International Federations (IFs) employ specific policies to protect athletes\' health from the danger of heat. Most policies rely on the measurement of thermal indices such as the Wet Bulb Globe Temperature (WBGT) to estimate the risk of heat-related illness. This review summarises the policies implemented by the 32 IFs of the 45 sports included in the Paris 2024 Olympic Games. It provides details into the venue type, measured parameters, used thermal indices, measurement procedures, mitigation strategies and specifies whether the policy is a recommendation or a requirement. Additionally, a categorisation of sports\' heat stress risk is proposed. Among the 15 sports identified as high, very high or extreme risk, one did not have a heat policy, three did not specify any parameter measurement, one relied on water temperature, two on air temperature and relative humidity, seven on WBGT (six measured on-site and one estimated) and one on the Heat Stress Index. However, indices currently used in sports have been developed for soldiers or workers and may not adequately reflect the thermal strain endured by athletes. Notably, they do not account for the athletes\' high metabolic heat production and their level of acclimation. It is, therefore, worthwhile listing the relevance of the thermal indices used by IFs to quantify the risk of heat stress, and in the near future, develop an index adapted to the specific needs of athletes.
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  • 文章类型: Journal Article
    世界各地的卫生机构历来警告说,电风扇在炎热的天气和热浪(通常在空气温度≥35°C)时会加速体热的增加。然而,自2021年以来发布的指南建议,风扇仍然可以通过促进汗水蒸发来在高达40°C的空气温度下冷却身体,因此是一种廉价但可持续的空调替代品。在对支持这一主张的引用报告的批判性分析中,我们发现,虽然风扇的使用改善了汗水蒸发,这些好处不足以在超过35°C的空气温度下有效降低身体核心温度。卫生机构应继续建议不要在高于35°C的空气温度下使用风扇,尤其是对于出汗能力受损的人(例如,65岁或以上的成年人)。改善对环境冷却策略的访问(例如,空调或蒸发冷却器),并通过政策举措将其经济和环境成本降至最低,高效的冷却技术,并结合使用低成本的个人干预措施(例如,皮肤润湿或风扇使用)对于气候适应至关重要。
    Health agencies worldwide have historically cautioned that electric fans accelerate body-heat gain during hot weather and heatwaves (typically in air temperatures ≥35°C). However, guidance published since 2021 has suggested that fans can still cool the body in air temperatures up to 40°C by facilitating sweat evaporation, and therefore are an inexpensive yet sustainable alternative to air conditioning. In a critical analysis of the reports cited to support this claim, we found that although fan use improves sweat evaporation, these benefits are of insufficient magnitude to exert meaningful reductions in body core temperature in air temperatures exceeding 35°C. Health agencies should continue to advise against fan use in air temperatures higher than 35°C, especially for people with compromised sweating capacity (eg, adults aged 65 years or older). Improving access to ambient cooling strategies (eg, air conditioning or evaporative coolers) and minimising their economic and environmental costs through policy initiatives, efficient cooling technology, and combined use of low-cost personal interventions (eg, skin wetting or fan use) are crucial for climate adaptation.
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  • 文章类型: Journal Article
    灵长类动物面临气候变化的严峻挑战,随着气候变暖预计会增加动物的体温调节需求。灵长类动物应对气候变化的长期选择有限,但具有显著的行为可塑性。这就迫切需要更好地了解灵长类动物用于温度调节的行为机制。虽然关于灵长类动物行为体温调节的信息相当多,它通常以难以整合的方式分散在文献中。这篇综述评估了有关灵长类动物行为体温调节的现有文献的现状,以促进未来的研究。我们调查了四个体温调节类别中N=17行为的灵长类动物体温调节的同行评审出版物:活动预算,微生境的使用,身体定位,和蒸发冷却。我们记录了评估的灵长类类群的数据,支持温度调节功能,热变量评估,和自然主义/操纵性研究条件。行为体温调节在灵长类动物中普遍存在,在N=284个已发表的研究中确定了N=721例体温调节行为。已知大多数属利用多种行为(x“=4.5±3.1行为/属)。活动预算行为是文献中最常见的类别(54.5%的案例),而蒸发冷却行为最少(6.9%的病例)。某些分类群体的行为体温调节研究代表性不足,包括狐猴,Lorises,加拉戈斯,和中美洲/南美洲灵长类动物,并且在属的代表中存在很大的类群内差异。对体温调节功能的支持在所有行为中都很高,跨越热回避和冷回避策略。这篇综述揭示了当前文献中的不对称性和未来研究的途径。需要更多地了解温度调节行为对生物学相关结果的影响,以更好地评估灵长类动物对变暖环境的反应并开发热应激的早期指标。
    Primates face severe challenges from climate change, with warming expected to increase animals\' thermoregulatory demands. Primates have limited long-term options to cope with climate change, but possess a remarkable capacity for behavioral plasticity. This creates an urgency to better understand the behavioral mechanisms primates use to thermoregulate. While considerable information exists on primate behavioral thermoregulation, it is often scattered in the literature in a manner that is difficult to integrate. This review evaluates the status of the available literature on primate behavioral thermoregulation to facilitate future research. We surveyed peer-reviewed publications on primate thermoregulation for N = 17 behaviors across four thermoregulatory categories: activity budgeting, microhabitat use, body positioning, and evaporative cooling. We recorded data on the primate taxa evaluated, support for a thermoregulatory function, thermal variable assessed, and naturalistic/manipulative study conditions. Behavioral thermoregulation was pervasive across primates, with N = 721 cases of thermoregulatory behaviors identified across N = 284 published studies. Most genera were known to utilize multiple behaviors ( x ¯  = 4.5 ± 3.1 behaviors/genera). Activity budgeting behaviors were the most commonly encountered category in the literature (54.5% of cases), while evaporative cooling behaviors were the least represented (6.9% of cases). Behavioral thermoregulation studies were underrepresented for certain taxonomic groups, including lemurs, lorises, galagos, and Central/South American primates, and there were large within-taxa disparities in representation of genera. Support for a thermoregulatory function was consistently high across all behaviors, spanning both hot- and cold-avoidance strategies. This review reveals asymmetries in the current literature and avenues for future research. Increased knowledge of the impact thermoregulatory behaviors have on biologically relevant outcomes is needed to better assess primate responses to warming environments and develop early indicators of thermal stress.
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  • 文章类型: Journal Article
    早产儿体温异常与发病率和死亡率增加有关。早产的婴儿在分娩室(DR)出生后立即有温度异常的风险。世界卫生组织(WHO)建议新生儿出生后的体温保持在36.5-37.5℃之间。当照顾早产儿时,国际复苏联络委员会(ILCOR)建议采用综合干预措施来防止热量损失.虽然体温过低仍然很普遍,努力预防它增加了高热的发生率,这也可能是有害的。自2015年以来,ILCOR建议对早产儿进行延迟脐带夹紧(DCC)。关于DCC的时间对温度的影响知之甚少,DCC之前也没有关于热护理的具体建议。这篇综述文章主要介绍DR中热护理的当前证据和建议,并在新兴干预措施和未来研究方向的背景下考虑体温调节。影响:温度异常在出生后的早产儿中很常见,是死亡的独立危险因素。目前的指南建议采取综合干预措施来防止出生后的热量流失。尽管如此,温度异常仍然是一个问题,在所有的气候和经济。新的和新兴的产房实践(即,延迟的电线夹紧,移动式复苏手推车,早期皮肤对皮肤护理)可能会影响婴儿的体温。本文回顾了当前的证据和建议,并对未来的研究方向进行了思考。
    Abnormal temperature in preterm infants is associated with increased morbidity and mortality. Infants born prematurely are at risk of abnormal temperature immediately after birth in the delivery room (DR). The World Health Organization (WHO) recommends that the temperature of newly born infants is maintained between 36.5-37.5oC after birth. When caring for very preterm infants, the International Liaison Committee on Resuscitation (ILCOR) recommends using a combination of interventions to prevent heat loss. While hypothermia remains prevalent, efforts to prevent it have increased the incidence of hyperthermia, which may also be harmful. Delayed cord clamping (DCC) for preterm infants has been recommended by ILCOR since 2015. Little is known about the effect of timing of DCC on temperature, nor have there been specific recommendations for thermal care before DCC. This review article focuses on the current evidence and recommendations for thermal care in the DR, and considers thermoregulation in the context of emerging interventions and future research directions. IMPACT: Abnormal temperature is common amongst very preterm infants after birth, and is an independent risk factor for mortality. The current guidelines recommend a combination of interventions to prevent heat loss after birth. Despite this, abnormal temperature is still a problem, across all climates and economies. New and emerging delivery room practice (i.e., delayed cord clamping, mobile resuscitation trolleys, early skin to skin care) may have an effect on infant temperature. This article reviews the current evidence and recommendations, and considers future research directions.
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  • 文章类型: Journal Article
    本研究旨在确定运动前水分过多对耐力表现(主要结果)的影响,心率,体温调节和知觉反应(次要结果)。截至2023年2月,共检索了六个学术数据库。仅包括报告干预和安慰剂/对照之间水合作用差异的研究。荟萃分析确定的总体效应大小(对冲),和元回归独立减速者的影响(环境温度,高水合剂,锻炼模式,水合过度的程度)。总的来说,10个出版物为主要结果生成19个效果估计,和11个出版物报告了48个次要结果的效应估计,包括在内。在过度水合后发现耗尽时间(TTE)(Hedges\'g=0.31,95%CI:0.13至0.50,p=0.001)和时间试验(TT)(g=0.25,95%CI:0.002至0.51,p=0.049))略有改善,但未发现总工作(TW)任务(p=0.120)。没有观察到调节作用。在稳态(SS)运动(p=0.069)或表现任务(p=0.072)后,未发现过度水合对心率的影响,对于体温后SS(p=0.132)或性能后任务(p=0.349),但是钠与甘油的荟萃回归显示,钠在执行任务后的体温较低(g=0.80,t(5)=2.65,p=0.046)。没有发现对感觉到的劳累或热舒适的影响。研究异质性低,缺乏精英和女运动员的代表性,和承重(即,跑步)锻炼方式。这些结果表明,运动前的水分过多对TTE和TT的耐力表现提供了小到中等的益处,但不是TW性能任务。虽然没有观察到调节作用,缺乏异质性使得这些发现很难一概而论。PROSPERO(CRD42021293146)。
    This study aimed to determine the effect of pre-exercise hyperhydration on endurance performance (primary outcome), heart rate, thermoregulation, and perceptual responses (secondary outcomes). Six academic databases were searched to February 2023. Only studies reporting differences in hydration between intervention and placebo/control were included. Meta-analysis determined overall effect size (Hedges\' g), and meta-regression the influence of independent moderators (ambient temperature, hyperhydration agent, exercise mode, extent of hyperhydration). Overall, 10 publications generating 19 effect estimates for primary outcomes, and 11 publications reporting 48 effect estimates for secondary outcomes, were included. A small-to-moderate improvement in time-to-exhaustion (TTE) (Hedges\' g = 0.31, 95% CI: 0.13-0.50, p = 0.001) and time trial (TT) (g = 0.25, 95% CI: 0.002-0.51, p = 0.049) but not total work (TW) tasks (p = 0.120) was found following hyperhydration. No moderating effects were observed. No effect of hyperhydration was found for heart rate following steady state (SS) exercise (p = 0.069) or the performance task (p = 0.072), nor for body temperature post-SS (p = 0.132) or post-performance task (p = 0.349), but meta-regression of sodium versus glycerol showed lower body temperature post-performance task with sodium (g = 0.80, t (5) = 2.65, p = 0.046). No effects were found for perceived exertion or thermal comfort. Study heterogeneity was low, lacking representation of elite and female athletes, and weight-bearing (i.e., running) exercise modalities. These results suggest pre-exercise hyperhydration provides a small-to-moderate benefit to endurance performance in TTE and TT, but not TW performance tasks. While no moderating effects were observed, lack of heterogeneity makes it difficult to generalise these findings.
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  • 文章类型: Journal Article
    背景:经常期望运动员和军事人员在炎热和/或潮湿的环境中竞争和工作,在那里,性能下降和劳累性热病的风险增加是普遍的。减少热应激的不利影响的生理策略是适应热。
    目的:本系统评价的目的是量化运动员和军事人员迁居到较热气候以进行热适应的影响。
    方法:研究调查了非适应运动员和军事人员通过搬迁到炎热气候<6周的热适应影响。
    方法:MEDLINE,SPORTDiscus,CINAHLPlus与全文和Scopus从开始到2022年6月进行了搜索。
    两名作者独立使用了McMaster批判性审查表的修改版本来评估偏倚的风险。
    结果:对五种结局指标进行了贝叶斯多水平荟萃分析,包括静息核心温度和心率,热反应测试期间核心温度和心率的变化和出汗率。湿球温度(WBGT),每日训练持续时间和方案长度被用作预测变量.连同后验均值和90%可信区间(CrI),计算方向概率(Pd)。
    结果:纳入了来自12项独立研究的18篇文章。14篇文章(9项研究)为荟萃分析提供了数据。在考虑WBGT的同时,每日训练持续时间和协议长度,人口估计表明静息核心温度和心率降低-0.19°C[90%CrI:-0.41至0.05,Pd=91%]和-6次搏动·min-1[90%CrI:-16至5,Pd=83%],分别。此外,热反应测试期间核心温度和心率的升高减弱了-0.24°C[90%CrI:-0.67至0.20,Pd=85%]和-7次·min-1[90%CrI:-18至4,Pd=87%]。出汗率的变化是矛盾的(0.01L·h-1[90%CrI:-0.38至0.40,Pd=53%]),主要是由于两项研究表明热适应后出汗率降低。
    结论:运动员和军事人员搬迁到更热气候的数据与静息核心温度和心率的降低是一致的,除了在基于运动的热反应测试期间核心温度和心率的衰减上升。出汗率的增加也是可以实现的,这些适应的程度取决于WBGT,每日训练持续时间和协议长度。
    CRD4202233761。
    BACKGROUND: Athletes and military personnel are often expected to compete and work in hot and/or humid environments, where decrements in performance and an increased risk of exertional heat illness are prevalent. A physiological strategy for reducing the adverse effects of heat stress is to acclimatise to the heat.
    OBJECTIVE: The aim of this systematic review was to quantify the effects of relocating to a hotter climate to undergo heat acclimatisation in athletes and military personnel.
    METHODS: Studies investigating the effects of heat acclimatisation in non-acclimatised athletes and military personnel via relocation to a hot climate for < 6 weeks were included.
    METHODS: MEDLINE, SPORTDiscus, CINAHL Plus with Full Text and Scopus were searched from inception to June 2022.
    UNASSIGNED: A modified version of the McMaster critical review form was utilised independently by two authors to assess the risk of bias.
    RESULTS: A Bayesian multi-level meta-analysis was conducted on five outcome measures, including resting core temperature and heart rate, the change in core temperature and heart rate during a heat response test and sweat rate. Wet-bulb globe temperature (WBGT), daily training duration and protocol length were used as predictor variables. Along with posterior means and 90% credible intervals (CrI), the probability of direction (Pd) was calculated.
    RESULTS: Eighteen articles from twelve independent studies were included. Fourteen articles (nine studies) provided data for the meta-analyses. Whilst accounting for WBGT, daily training duration and protocol length, population estimates indicated a reduction in resting core temperature and heart rate of - 0.19 °C [90% CrI: - 0.41 to 0.05, Pd = 91%] and - 6 beats·min-1 [90% CrI: - 16 to 5, Pd = 83%], respectively. Furthermore, the rise in core temperature and heart rate during a heat response test were attenuated by - 0.24 °C [90% CrI: - 0.67 to 0.20, Pd = 85%] and - 7 beats·min-1 [90% CrI: - 18 to 4, Pd = 87%]. Changes in sweat rate were conflicting (0.01 L·h-1 [90% CrI: - 0.38 to 0.40, Pd = 53%]), primarily due to two studies demonstrating a reduction in sweat rate following heat acclimatisation.
    CONCLUSIONS: Data from athletes and military personnel relocating to a hotter climate were consistent with a reduction in resting core temperature and heart rate, in addition to an attenuated rise in core temperature and heart rate during an exercise-based heat response test. An increase in sweat rate is also attainable, with the extent of these adaptations dependent on WBGT, daily training duration and protocol length.
    UNASSIGNED: CRD42022337761.
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  • 文章类型: Journal Article
    在不同的气候条件下,牛将体温控制在狭窄的范围内。体内的热量是通过新陈代谢产生的,消化和活动。辐射是热量传递到牛体内的主要外部来源。牛体内疗法使用行为和生理控制来管理辐射,对流,传导,身体和环境之间的蒸发热交换,注意到蒸发机制几乎完全将身体热量传递给环境。牛通过寻找阴影(热)和庇护所(冷)以及拥挤或站得更远来控制辐射,注意到辐射转移潜力存在内在的品种和年龄差异。皮肤和外部环境之间的温度梯度和风速(对流)决定了通过这些手段的热传递。牛通过管理流向外周的血液(生理学)来控制这些机制,通过短期(行为上)寻求庇护所和站立/躺着活动,并通过长期(适应环境)修改其外套并调整其代谢率。牛的蒸发热损失主要来自出汗,有一些呼吸贡献,当环境温度超过皮肤温度(〜36°C)时,它是散发多余热量的主要机制。牛倾向于更好地适应较冷而不是较热的外部条件,与Bosindicus相比,Bosindicus的品种更适应高温条件。管理可以通过确保适当适应的牛的适当品种来最大程度地减少热应力的风险,在适当的放养密度下,喂适当的饮食(和水),并获得合适的住所和通风更适合其预期的农场环境。
    Cattle control body temperature in a narrow range over varying climatic conditions. Endogenous body heat is generated by metabolism, digestion and activity. Radiation is the primary external source of heat transfer into the body of cattle. Cattle homeothermy uses behavioural and physiological controls to manage radiation, convection, conduction, and evaporative exchange of heat between the body and the environment, noting that evaporative mechanisms almost exclusively transfer body heat to the environment. Cattle control radiation by shade seeking (hot) and shelter (cold) and by huddling or standing further apart, noting there are intrinsic breed and age differences in radiative transfer potential. The temperature gradient between the skin and the external environment and wind speed (convection) determines heat transfer by these means. Cattle control these mechanisms by managing blood flow to the periphery (physiology), by shelter-seeking and standing/lying activity in the short term (behaviourally) and by modifying their coats and adjusting their metabolic rates in the longer term (acclimatisation). Evaporative heat loss in cattle is primarily from sweating, with some respiratory contribution, and is the primary mechanism for dissipating excess heat when environmental temperatures exceed skin temperature (~36°C). Cattle tend to be better adapted to cooler rather than hotter external conditions, with Bos indicus breeds more adapted to hotter conditions than Bos taurus. Management can minimise the risk of thermal stress by ensuring appropriate breeds of suitably acclimatised cattle, at appropriate stocking densities, fed appropriate diets (and water), and with access to suitable shelter and ventilation are better suited to their expected farm environment.
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  • 文章类型: Meta-Analysis
    目的:麻醉诱导后预防围手术期体温过低是腹部手术患者的重要问题。当应用于身体的特定区域时,各种加温系统用于防止体温过低和发抖的有效性仍未确定。
    方法:系统评价和网络荟萃分析。
    方法:手术室。
    方法:搜索了五个电子数据库,仅包括随机对照试验(RCTs),这些试验报告了应用于特定身体部位的加温系统对腹部手术成人术中核心温度和术后寒战风险的影响。实施了具有频率论框架的多元随机效应网络荟萃分析以进行数据分析。
    方法:主要结果是腹部手术麻醉诱导后60和120分钟的核心体温。次要结果是术后寒战的发生率。
    结果:本综述共包括24项RCTs,包括1119例患者。麻醉诱导后60和120分钟,适用于上身的强制空气加温系统(0.3°C和95%置信区间=[0.3至0.4],1.0°C[0.7至1.3]),下体(0.4°C[0.3至0.5],0.9°C[0.5至1.2]),和车底(0.5°C[0.5至0.6],1.2°C[0.9至1.6])在核心体温调节方面优于被动绝缘。与被动绝缘相比,应用于下半身(比值比=0.06)或下半身(0.44)的强制空气加温系统和应用于下半身(0.02)或全身(0.07)的电热毯显著降低了发抖的风险。
    结论:该NMA的结果表明,在麻醉诱导后60和120分钟内,用人体下毯进行强制空气加温可有效提高核心体温,并防止从腹部手术恢复的患者发抖。
    The prevention of perioperative hypothermia after anesthesia induction is a critical concern in patients undergoing abdominal surgery. The effectiveness of various warming systems for preventing hypothermia and shivering when applied to specific areas of the body remains undetermined.
    Systematic review and network meta-analysis.
    Operating room.
    Five electronic databases were searched, including only randomized control trials (RCTs) reporting the effects of warming systems applied to specific body sites on the intraoperative core temperature and postoperative risk of shivering in adults undergoing abdominal surgery. A multivariate random-effects network meta-analysis with a frequentist framework was implemented for data analysis.
    The primary outcome was the core body temperature 60 and 120 min after anesthesia induction for abdominal surgery. The secondary outcome was the incidence of postoperative shivering.
    This review comprised a total of 24 RCTs including 1119 patients. At 60 and 120 min after anesthesia induction, a forced-air warming system applied to the upper body (0.3 °C and 95% confidence intervals = [0.3 to 0.4], 1.0 °C [0.7 to 1.3]), lower body (0.4 °C [0.3 to 0.5], 0.9 °C [0.5 to 1.2]), and underbody (0.5 °C [0.5 to 0.6], 1.2 °C [0.9 to 1.6]) was superior to passive insulation in terms of core body temperature regulation. Compared with passive insulation, the forced-air warming system applied to the lower body (odds ratio = 0.06) or underbody (0.44) and the electric heating blanket to the lower body (0.02) or the whole body (0.07) significantly reduced the risk of shivering.
    The results of this NMA revealed that forced-air warming with an underbody blanket effectively elevates core body temperatures in 60 and 120 min after induction of anesthesia and prevents shivering in patients recovering from abdominal surgery.
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  • 文章类型: Meta-Analysis
    背景:热适应制度用于为运动员在炎热条件下进行锻炼做准备,以限制运动表现的下降。然而,热适应文献主要关注男性,因此,当考虑到两性之间的生物学和表型差异时,当前的热适应指南可能不是女性的最佳选择。
    目的:我们旨在研究:(1)热适应对女性生理适应的影响;(2)热适应对高温性能测试结果的影响;(3)各种调节剂的影响,包括持续时间(分钟和/或天数),总热剂量(℃。min),运动强度(千卡。min-1),消耗的总能量(大卡),热暴露的频率和训练状态对热中生理适应的影响。
    方法:SPORTDiscus,搜索MEDLINEComplete和Embase数据库至2022年12月。静息和运动核心温度的随机效应荟萃分析,皮肤温度,心率,出汗率,使用Stata统计软件:版本17完成加热中的等离子体体积和性能测试。进行亚组荟萃分析,以探讨持续时间的影响,总热剂量,运动强度,消耗的总能量,热暴露频率和休息和运动核心温度的训练状态,皮肤温度,心率和出汗率。进行了探索性元回归,以确定生理适应对热适应后热性能测试结果的影响。
    结果:30项研究纳入系统评价;22项研究进行荟萃分析。热适应后,静息核心温度降低(效应大小[ES]=-0.45;95%置信区间[CI]-0.69,-0.22;p<0.001),运动核心温度(ES=-0.81;95%CI-1.01,-0.60;p<0.001),皮肤温度(ES=-0.64;95%CI-0.79,-0.48;p<0.001),在女性中发现心率(ES=-0.60;95%CI-0.74,-0.45;p<0.001)和出汗率增加(ES=0.53;95%CI0.21,0.85;p=0.001).血浆体积没有变化(ES=-0.03;95%CI-0.31,0.25;p=0.835),而热适应后性能测试结果有所改善(ES=1.00;95%CI0.56,1.45;p<0.001)。在所有主持人中,在451-900分钟和/或8-14天的持续时间后,更一致地观察到生理适应,运动强度≥3.5千卡。min-1,消耗的总能量≥3038千卡,连续(每日)频率和总热剂量≥23,000°C。min.热量表现测试结果的变化幅度与热量适应后心率降低有关(标准化平均差=-10次心跳。min-1;95%CI-19,-1;p=0.031)。
    结论:热适应机制诱导生理适应,有利于女性热量调节和性能测试结果。体育教练和应用体育从业者可以利用这篇评论中开发的框架来设计和实施女性的热适应策略。
    Heat adaptation regimes are used to prepare athletes for exercise in hot conditions to limit a decrement in exercise performance. However, the heat adaptation literature mostly focuses on males, and consequently, current heat adaptation guidelines may not be optimal for females when accounting for the biological and phenotypical differences between sexes.
    We aimed to examine: (1) the effects of heat adaptation on physiological adaptations in females; (2) the impact of heat adaptation on performance test outcomes in the heat; and (3) the impact of various moderators, including duration (minutes and/or days), total heat dose (°C.min), exercise intensity (kcal.min-1), total energy expended (kcal), frequency of heat exposures and training status on the physiological adaptations in the heat.
    SPORTDiscus, MEDLINE Complete and Embase databases were searched to December 2022. Random-effects meta-analyses for resting and exercise core temperature, skin temperature, heart rate, sweat rate, plasma volume and performance tests in the heat were completed using Stata Statistical Software: Release 17. Sub-group meta-analyses were performed to explore the effect of duration, total heat dose, exercise intensity, total energy expended, frequency of heat exposure and training status on resting and exercise core temperature, skin temperature, heart rate and sweat rate. An explorative meta-regression was conducted to determine the effects of physiological adaptations on performance test outcomes in the heat following heat adaptation.
    Thirty studies were included in the systematic review; 22 studies were meta-analysed. After heat adaptation, a reduction in resting core temperature (effect size [ES] =  - 0.45; 95% confidence interval [CI] - 0.69, - 0.22; p < 0.001), exercise core temperature (ES =  - 0.81; 95% CI - 1.01, - 0.60; p < 0.001), skin temperature (ES =  - 0.64; 95% CI - 0.79, - 0.48; p < 0.001), heart rate (ES =  - 0.60; 95% CI - 0.74, - 0.45; p < 0.001) and an increase in sweat rate (ES = 0.53; 95% CI 0.21, 0.85; p = 0.001) were identified in females. There was no change in plasma volume (ES = - 0.03; 95% CI - 0.31, 0.25; p = 0.835), whilst performance test outcomes were improved following heat adaptation (ES = 1.00; 95% CI 0.56, 1.45; p < 0.001). Across all moderators, physiological adaptations were more consistently observed following durations of 451-900 min and/or 8-14 days, exercise intensity ≥ 3.5 kcal.min-1, total energy expended ≥ 3038 kcal, consecutive (daily) frequency and total heat dose ≥ 23,000 °C.min. The magnitude of change in performance test outcomes in the heat was associated with a reduction in heart rate following heat adaptation (standardised mean difference =  - 10 beats.min-1; 95% CI - 19, - 1; p = 0.031).
    Heat adaptation regimes induce physiological adaptations beneficial to thermoregulation and performance test outcomes in the heat in females. Sport coaches and applied sport practitioners can utilise the framework developed in this review to design and implement heat adaptation strategies for females.
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  • 文章类型: Journal Article
    已提出目标温度管理(TTM)以降低心脏骤停后和其他危重病人的死亡率并改善神经系统预后。TTM的实施可能因医院而异,和“高质量TTM”定义不一致。有关重症监护条件的系统文献综述评估了TTM质量在预防发烧和维持精确温度控制方面的方法和定义。关于心脏骤停中与TTM相关的发热管理质量的当前证据,创伤性脑损伤,中风,脓毒症,和重症监护更普遍的检查。根据PRISMA指南,在Embase和PubMed(2016年至2021年)中进行了搜索。总的来说,确定并纳入了37项研究,35岁的人专注于最贫穷的护理。经常报告的TTM质量结局包括反弹热疗的患者数量,与目标温度的偏差,TTM后体温,以及达到目标温度的患者数量。在13项研究中使用了表面和血管内冷却,一项研究使用表面和体外冷却,一项研究使用表面冷却和退烧药。表面和血管内方法在达到目标温度和维持温度方面具有相当的速率。一项研究表明,表面冷却的患者回弹高热的发生率较低。本系统文献综述在很大程度上确定了心脏骤停文献,证明了使用多种TTM方法预防发烧。在质量TTM的定义和交付方面存在显著的异质性。需要进一步的研究来定义跨多个元素的质量TTM,包括达到目标温度,保持目标温度,防止反弹过热。
    Targeted temperature management (TTM) has been proposed to reduce mortality and improve neurological outcomes in postcardiac arrest and other critically ill patients. TTM implementation may vary considerably among hospitals, and \"high-quality TTM\" definitions are inconsistent. This systematic literature review in relevant critical care conditions evaluated the approaches to and definitions of TTM quality with respect to fever prevention and the maintenance of precise temperature control. Current evidence on the quality of fever management associated with TTM in cardiac arrest, traumatic brain injury, stroke, sepsis, and critical care more generally was examined. Searches were conducted in Embase and PubMed (2016 to 2021) following PRISMA guidelines. In total, 37 studies were identified and included, with 35 focusing on postarrest care. Frequently-reported TTM quality outcomes included the number of patients with rebound hyperthermia, deviation from target temperature, post-TTM body temperatures, and number of patients achieving target temperature. Surface and intravascular cooling were used in 13 studies, while one study used surface and extracorporeal cooling and one study used surface cooling and antipyretics. Surface and intravascular methods had comparable rates of achieving target temperature and maintaining temperature. A single study showed that patients with surface cooling had a lower incidence of rebound hyperthermia. This systematic literature review largely identified cardiac arrest literature demonstrating fever prevention with multiple TTM approaches. There was substantial heterogeneity in the definitions and delivery of quality TTM. Further research is required to define quality TTM across multiple elements, including achieving target temperature, maintaining target temperature, and preventing rebound hyperthermia.
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