围手术期无意的低体温,定义为核心体温低于36.0°C,会对手术患者造成严重后果。这些包括心脏并发症,失血量增加,伤口感染和术后发抖;因此,应避免意外的围手术期低温的科学证据是无可争议的,一些国家指南已经发表,总结了科学证据并推荐了具体的手术.德国AWMF指南首次强调了预热对手术患者的重要性,以避免意外的围手术期体温过低;然而,与术中加温相比,到目前为止,在许多医院的临床实践中,预热还没有充分实施。此外,最近的一项研究质疑预热的有效性。
这项回顾性研究的目的是评估将麻醉诱导室预热引入临床实践并进行术中预热时可达到的低体温率。
马丁路德大学医学院的伦理委员会批准了麻醉数据库中的数据存储和回顾性数据分析。根据现有的当地标准操作程序,在2015年1月至2016年12月期间,3899例接受全身麻醉,持续时间30min或更长的患者,除了术中在麻醉诱导室加温外,还进行了强制空气预加温.将结果与2012年7月至2014年8月接受术中加温但未进行预热的3887名患者的对照组进行比较。所有患者均进行气管插管,并在麻醉诱导后使用食管进行体温测量,导尿管或动脉内温度探头。
治疗组中预热的平均持续时间为25分钟。接受预热的患者术中低温率为15.8%,术后低温率为5.1%。未预热的患者术中低体温率为30.4%,术后低体温率为12.4%。这意味着术中低温发生率降低52%,术后低温发生率降低41%(p<0.0001)。多因素logistic回归显示,缺乏预热与术中低体温独立相关,比值比为2.5(95%置信区间2.250-2.841;p<0.0001),术后低体温相关,比值比为2.8(95%CI2.316-3.277;p<0.0001)。
预热,按照AWMF指南中的建议,导致意外的围手术期体温过低的发生率显着降低且临床相关;因此,预热仍可视为避免围术期低体温的有效方法。在临床实践中可以达到15.8%的术中和5.1%的术后低体温率,在手术开始之前,除了在麻醉诱导室中进行术中加热之外,还进行了预热。
Inadvertent perioperative hypothermia, which is defined as a core body temperature of less than 36.0 °C, can have serious consequences in surgery patients. These include cardiac complications, increased blood loss, wound infections and postoperative shivering; therefore, the scientific evidence that inadvertent perioperative hypothermia should be avoided is undisputed and several national
guidelines have been published summarizing the scientific evidence and recommending specific procedures. The German AWMF
guidelines were the first to emphasize the importance of prewarming for surgery patients to avoid inadvertant perioperative hypothermia; however, in contrast to intraoperative warming, prewarming is so far not sufficiently implemented in clinical practice in many hospitals. Furthermore, a recent study has questioned the effectiveness of prewarming.
The aim of this retrospective investigation was to evaluate the hypothermia rates that can be achieved when prewarming in the anesthesia induction room is introduced into the clinical practice and performed in addition to intraoperative warming.
The ethics committee of the Medical Faculty of the Martin Luther University Halle Wittenberg gave approval for data storage and retrospective data analysis from the anesthesia database. According to the existing local standard operating procedure, prewarming with forced air was performed in addition to intraoperative warming in the anesthesia induction room in 3899 patients receiving general anesthesia with a duration of 30 min or longer from January 2015 to December 2016. The results were compared with a control group of 3887 patients from July 2012 to August 2014 who received intraoperative warming but were not subjected to prewarming. Tracheal intubation was carried out in all patients and temperature measurements after the induction of anesthesia were performed using esophageal, urinary catheter or intra-arterial temperature probes.
The mean duration of prewarming was 25 min in the treatment group. Patients subjected to prewarming showed an intraoperative hypothermia rate of 15.8% and a postoperative hypothermia rate of 5.1%. Patients without prewarming showed an intraoperative hypothermia rate of 30.4% and a postoperative hypothermia rate of 12.4%. This means a 52% reduction of the intraoperative hypothermia rate and a 41% reduction of the postoperative hypothermia rate for patients who received prewarmimg (p < 0.0001). Multivariate logistic regression revealed that the lack of prewarming was independently associated with intraoperative hypothermia with an odds ratio of 2.5 (95% confidence interval CI 2.250-2.841; p < 0.0001) and postoperative hypothermia with an odds ratio of 2.8 (95% CI 2.316-3.277; p < 0.0001).
Prewarming, as recommended in the AWMF
guidelines, resulted in a significant and clinically relevant reduction in the incidence of inadvertent perioperative hypothermia; therefore, prewarming can still be regarded as an effective method to avoid perioperative hypothermia. Hypothermia rates of 15.8% intraoperatively and 5.1% postoperatively can be achieved in clinical practice, when prewarming is performed in addition to intraoperative warming in the anesthesia induction room directly before the start of surgical procedures.