目的:报告不同类型的Duane`s收缩综合征(DRS)患者的视觉和屈光特征以及弱视的患病率。
方法:这项回顾性研究是对Farabi医院582名DRS患者的住院记录进行的,伊朗,从2012年到2022年3月。
结果:患者的平均年龄为19.4±11.9(范围,3-70岁)[335(57.6%)女性和247(42.4%)男性(P<.001)]。I型DRS,II,III,和IV出现在347(59.6%),148(25.4%),82(14.1%),和5名(0.9%)患者,分别。单侧受累的患者为530例(91.1%),双侧受累的患者为52例(8.9%)。在单侧患者中,DRS眼矫正视力(CDVA)和散光明显低于非DRS眼(P<.001)。双侧患者右眼或左眼的所有屈光参数和视觉参数的平均值均显着低于单侧患者的非DRS眼(均P<0.05)。75例(12.9%)患者出现屈光参差。在单侧和双侧DRS患者中,弱视发生率为18.5%(98例)和36.5%(19例)。分别(P<.001)。在单侧患者中,弱视发生在57例(16.4%)I型患者中,22例(14.9%)II型患者,16例(19.5%)III型患者,和3(60%)IV型患者。弱视患者中有44例(37.6%)患有屈光参差。
结论:这项大规模研究表明,DRS类型在屈光不正方面有所不同,视敏度,弱视和屈光参差的患病率。临床医生应了解与不同类型DRS相关的临床特征。
OBJECTIVE: To report the visual and refractive characteristics and the prevalence of amblyopia in patients with different types of Duane\'s Retraction Syndrome (DRS).
METHODS: This retrospective study was performed on hospital records of 582 DRS patients at Farabi Hospital, Iran, from 2012 to March 2022.
RESULTS: The mean age of patients was 19.4 ± 11.9 (range, 3-70) years [335 (57.6 %) females and 247 (42.4 %) males (P < .001)]. DRS type I, II, III, and IV were presented in 347 (59.6 %), 148 (25.4 %), 82 (14.1 %), and 5 (0.9 %) patients, respectively. There were 530 (91.1 %) patients with unilateral and 52 (8.9 %) with bilateral involvement. In the unilateral patients, the DRS eyes\' corrected distance visual acuity (CDVA) and astigmatism were significantly worse than the Non-DRS Eyes (P < .001). The mean amount of all refractive and visual parameters in bilateral patients\' right or left eyes was significantly lower than in unilateral patients\' non-DRS eyes (all P < .05).
Anisometropia was observed in 75(12.9 %) of the patients. Amblyopia was observed in 18.5 % (98 patients) and 36.5 % (19 patients) of unilateral and bilateral DRS patients, respectively (P < .001). In unilateral patients, amblyopia was found in 57 (16.4 %) patients with Type I, 22 (14.9 %) patients with Type II, 16 (19.5 %) patients with Type III, and 3 (60 %) patients with Type IV. Forty-four (37.6 %) of patients with amblyopia had
anisometropia.
CONCLUSIONS: This large-scale study indicates that DRS types differ in terms of refractive error, visual acuity, and the prevalence of amblyopia and
anisometropia. Clinicians should be aware of the clinical features associated with different types of DRS.