PDF(Pubmed)
Abstract：
Athletes are increasingly relying on natural supplements to improve athletic performance. Echinacea, a common herbal supplement, has been studied for its potential erythropoietin-enhancing effects, with mixed results in the literature. The purpose of this meta-analysis is to determine whether echinacea supplementation has erythropoietic or ergogenic effects in athletes. A search strategy was developed to identify trials studying the impact of echinacea supplementation on erythropoiesis and maximal oxygen uptake. The database search yielded 502 studies, 496 of which were excluded in the two-reviewer screening process. Six studies with a total of 107 athletes were included in the analysis. For hemoglobin and hematocrit levels, there were small, positive effect sizes when comparing the difference in pre- and post-intervention levels between the echinacea and placebo groups, at 0.38 (p = 0.02, 95% CI -0.04-0.80, I2 = 70%) and 0.34 (p < 0.01, 95% CI -0.10-0.78, I2 = 86%), respectively, though they did not reach statistical significance. There was also no statistically significant change in erythropoietin (effect size -0.29, p = 0.05, 95% CI -0.75-0.17, I2 = 67%) or maximal oxygen uptake (effect size -0.20, p = 0.95, 95% CI -0.60-0.21, I2 = 0%). Echinacea supplementation did not influence erythropoietin, hemoglobin, hematocrit, or maximal oxygen uptake in athletes; however, the evidence base is limited.
摘要：
运动员越来越依赖天然补充剂来提高运动成绩。紫锥菊,一种常见的草药补充剂，已经研究了其潜在的促红细胞生成素增强作用，文献中的结果好坏参半。这项荟萃分析的目的是确定紫锥菊补充剂在运动员中是否具有促红细胞生成或麦角作用。开发了一种搜索策略来确定研究紫锥菊补充剂对红细胞生成和最大摄氧量的影响的试验。数据库搜索产生了502项研究，其中496例被排除在两名审查者筛选过程中。共有107名运动员的6项研究被纳入分析。血红蛋白和血细胞比容水平，有小,当比较紫锥菊和安慰剂组之间干预前后水平的差异时，在0.38（p=0.02，95％CI-0.04-0.80，I2=70％）和0.34（p<0.01，95％CI-0.10-0.78，I2=86％），分别,虽然没有达到统计学意义。促红细胞生成素（效应大小-0.29，p=0.05，95％CI-0.75-0.17，I2=67％）或最大摄氧量（效应大小-0.20，p=0.95，95％CI-0.60-0.21，I2=0％）也没有统计学上的显着变化。紫锥菊补充剂不影响促红细胞生成素，血红蛋白,血细胞比容,或运动员的最大摄氧量；然而，证据基础有限。
