关键词: RNA-seq exploratory data analysis lipidomics metabolomics proteomics reproducibility software statistics visualization web service

Mesh : Humans Internet Lipidomics / methods Mass Spectrometry / methods Metabolomics / methods statistics & numerical data Multiomics / methods statistics & numerical data Proteomics / methods statistics & numerical data Software User-Computer Interface

来  源:   DOI:10.1021/acs.jproteome.3c00512

Abstract:
PMart is a web-based tool for reproducible quality control, exploratory data analysis, statistical analysis, and interactive visualization of \'omics data, based on the functionality of the pmartR R package. The newly improved user interface supports more \'omics data types, additional statistical capabilities, and enhanced options for creating downloadable graphics. PMart supports the analysis of label-free and isobaric-labeled (e.g., TMT, iTRAQ) proteomics, nuclear magnetic resonance (NMR) and mass-spectrometry (MS)-based metabolomics, MS-based lipidomics, and ribonucleic acid sequencing (RNA-seq) transcriptomics data. At the end of a PMart session, a report is available that summarizes the processing steps performed and includes the pmartR R package functions used to execute the data processing. In addition, built-in safeguards in the backend code prevent users from utilizing methods that are inappropriate based on omics data type. PMart is a user-friendly interface for conducting exploratory data analysis and statistical comparisons of omics data without programming.
摘要:
PMart是一个基于网络的可重复质量控制工具,探索性数据分析,统计分析,和“组学数据的交互式可视化,基于pmartRR包的功能。新改进的用户界面支持更多的组学数据类型,额外的统计能力,和用于创建可下载图形的增强选项。PMart支持无标签和等压标签的分析(例如,TMT,iTRAQ)蛋白质组学,核磁共振(NMR)和质谱(MS)为基础的代谢组学,基于MS的脂质组学,和核糖核酸测序(RNA-seq)转录组学数据。在PMart会议结束时,提供了一个报告,该报告总结了执行的处理步骤,并包括用于执行数据处理的pmartRR包函数。此外,后端代码中的内置防护措施可防止用户使用基于组学数据类型的不适当方法。PMart是一个用户友好的界面,用于在无需编程的情况下对组学数据进行探索性数据分析和统计比较。
公众号