SLFN5 介导的染色质动力学塑造了高阶 DNA 修复拓扑。
关键词: 53BP1 DNA double-strand break repair PARP inhibitor sensitivity SLFN5 chromatin mobility chromatin topology class switch recombination non-homologous end joining super-resolution microscopy telomere fusions
Mesh : Animals Chromatin / genetics DNA Breaks, Double-Stranded DNA End-Joining Repair DNA Repair Mammals / metabolism Telomere-Binding Proteins / genetics Tumor Suppressor p53-Binding Protein 1 / genetics metabolism Cell Cycle Proteins / metabolism
来 源:
DOI:10.1016/j.molcel.2023.02.004
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