spontaneous

自发
  • 文章类型: Journal Article
    自发性气胸通常表现为医疗紧急情况,需要及时注意和治疗。在患有潜在肺部疾病的患者中,它通常与长期住院有关,持续的漏气和高复发率。它给患者带来了相当大的临床负担,因此人们热切期待自发性气胸管理的进步。近年来,对于临床稳定且症状轻微的原发性自发性气胸(PSP)患者,避免采用侵入性治疗的保守治疗已成为主要考虑因素.与PSP组相比,继发性自发性气胸(SSP)组的证据较少。由于担心手术胸膜固定术后的发病率和死亡率,SSP的非手术治疗变得越来越普遍,因为患者通常年龄较大,患有更多的潜在医学疾病。直到去年,自2010年英国胸科学会(BTS)指南发布以来,国际上关于气胸治疗的建议没有更新.最新的2023BTS胸膜疾病指南为我们提供了一个很好的机会来回顾自发性气胸患者护理的最新进展和文献。本文将探讨气胸治疗的目标,包括空气疏散,停止持续的空气泄漏和预防复发。
    Spontaneous pneumothorax usually presents as a medical emergency and requires prompt attention and treatment. In patients with underlying lung diseases, it is often associated with prolonged hospitalization, persistent air leak and also a high rate of recurrence. It brings considerable clinical burden to patients and therefore advancement of spontaneous pneumothorax management is eagerly anticipated. In recent years, conservative approach with avoidance of invasive treatment has risen to be a main consideration for primary spontaneous pneumothorax (PSP) patients who are clinically stable with minimal symptoms. The body of evidence in secondary spontaneous pneumothorax (SSP) group is less robust compared with that in PSP group. Non-surgical treatment in SSP is becoming more common due to concerns about morbidity and mortality after surgical pleurodesis as patients are usually older with more underlying medical diseases. Until last year, there have been no updates on the international recommendation of pneumothorax management since the British Thoracic Society (BTS) guideline published in 2010. The latest 2023 BTS guideline on pleural diseases provides us a good opportunity to review the latest development and literature of the care for patients with spontaneous pneumothorax. This article will explore the goals of pneumothorax treatment including air evacuation, cessation of persistent air leak and prevention of recurrence.
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  • 文章类型: Case Reports
    股四头肌腱,对身体运动至关重要,是身体最强壮的肌腱之一。糖尿病或激素使用等因素会削弱它,即使是轻微的创伤也可能导致破裂。双侧自发性股四头肌腱断裂,两个肌腱同时撕裂,是罕见的。及时的诊断和治疗至关重要。我们介绍了一例44岁的女性,她在做家务时摔倒后发生了双侧破裂。她立即疼痛,膝盖活动受限。通过体格检查和CT/MRI扫描诊断证实了破裂。手术修复后康复可在两个月内明显减轻疼痛并改善功能。总的来说,她的术后结局令人满意。这项研究强调了明确诊断的重要性,及时手术,和彻底的康复,以使患者从双侧股四头肌腱断裂中恢复最佳。
    The quadriceps tendon, crucial for body movement, is among the body\'s strongest tendons. Factors like diabetes or hormone use can weaken it, making even minor trauma potentially causing rupture. Bilateral spontaneous quadriceps tendon rupture, where both tendons tear simultaneously, is rare. Prompt diagnosis and treatment are crucial. We present a case of a 44-year-old woman who experienced bilateral rupture after falling while doing chores. She had immediate pain and limited knee movement. Diagnosis via physical examination and CT/MRI scans confirmed the rupture. Surgical repair followed by rehabilitation led to significant pain reduction and improved function within two months. Overall, her postoperative outcome was satisfactory. This study underscores the importance of clear diagnosis, timely surgery, and thorough rehabilitation for optimal patient recovery from bilateral quadriceps tendon rupture.
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  • 文章类型: Journal Article
    目的:术中常规使用数字减影血管造影(iDSA)可提高显微手术夹闭后颅内动脉瘤(IA)残留的检出率。夹闭后IA残留物的自发性血栓形成被认为是罕见的现象。我们分析iDSA特征以找到IA残余血栓形成的预测因子。
    方法:IA术中检测到夹闭后的残余,并将其分为自发性血栓形成的残余,以及具有长期通畅性和/或残余生长的残余物。分析比较两组的iDSA血管造影特点。
    结果:在3D-iDSA上有术中残留的37个IAs中,5人维持了自发性残余血栓形成,并在长期随访中仍然闭塞.在所有五个案例中,iDSA显示造影剂的流入延迟和随后的停滞,直到静脉晚期。另一方面,在所有有持续性长期IA残留的病例(n=32)中,iDSA均显示出及时的动脉造影剂流入和流出,而动脉瘤内造影剂没有停滞.
    结论:在iDSA期间IA残留的对比血瘀似乎可以预测长期IA闭塞,表明在这些患者中可以避免对残余IA进行夹子矫正操作甚至尝试血管内治疗。
    OBJECTIVE: The routine use of intraoperative digital subtraction angiography (iDSA) increases detection of intracranial aneurysm (IA) remnants after microsurgical clipping. Spontaneous thrombosis of IA remnants after clipping is considered a rare phenomenon. We analyse iDSA characteristics to find predictors for IA remnant thrombosis.
    METHODS: IA with intraoperative detection of a remnant after clipping were identified and divided into remnants experiencing spontaneous thrombosis, and remnants with long-term patency and/or remnant growth. Angiographic features of iDSA were analysed and compared between the two groups.
    RESULTS: Of 37 IAs with intraoperative remnant on 3D-iDSA, five sustained a spontaneous remnant thrombosis and remained occluded in long-term follow-up. In all five cases, iDSA revealed delayed inflow and consequent stasis of the contrast agent until the late venous phase. On the other hand, in all cases with persistent long-term IA remnants (n = 32) iDSA demonstrated timely arterial contrast inflow and wash-out without stasis of intra-aneurysmal contrast agent.
    CONCLUSIONS: Contrast stasis in IA remnants during iDSA appears to predict long-term IA occlusion, indicating that clip correction manoeuvres or even attempted endovascular treatment of the remnant IA may be avoided in these patients.
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  • 文章类型: Journal Article
    不受控制的慢性荨麻疹(CU)会严重影响身体和社会心理健康以及生活质量。患者报告的结果指标对于衡量疾病控制至关重要。指南建议使用荨麻疹控制测试(UCT)来监测CU并指导临床管理。然而,UCT的繁体中文版本尚未得到验证。
    我们试图在香港的中国CU患者中验证传统的中国UCT。
    CU患者在香港荨麻疹参考和卓越中心(又名UCARE)注册,并完成了传统的中国UCT。内部一致性,测试-重测可靠性,构造效度,收敛有效性,已知组有效性,并评估了对传统中国UCT变化的敏感性。
    我们招募了162名CU患者(80.9%为女性;年龄50±14岁),平均(中位数)±标准偏差基线UCT评分为8.8(8)±4.7。总的来说,中国UCT表现出优异的内部一致性(Cronbachα和McDonaldω=0.948),以及重测信度(组内相关系数=0.916[95%置信区间=0.866-0.953])。探索性因子分析揭示了一维结构,并证实了其结构有效性。UCT与7天荨麻疹活动评分(UAS7)之间的强相关性证明了其收敛有效性(ρ=-0.699,P<.001)。其已知的组有效性得到了具有不同疾病活动的患者亚组之间明显不同的UCT评分的支持。中国UCT也表现出良好的变化敏感性,如UCT和UAS7评分变化之间的显著相关性所反映的(ρ=0.491,P<.001)。
    繁体中文UCT是有效的,可靠,以及香港华人与CU的敏感易变乐器。
    UNASSIGNED: Uncontrolled chronic urticaria (CU) can severely affect physical and psychosocial health as well as quality of life. Patient-reported outcome measures are crucial for measuring disease control. The Urticaria Control Test (UCT) is recommended by guidelines to monitor CU and guide clinical management. However, the traditional Chinese version of the UCT has not yet been validated.
    UNASSIGNED: We sought to validate the traditional Chinese UCT among Chinese CU patients in Hong Kong.
    UNASSIGNED: Patients with CU were enrolled at a Urticaria Centre of Reference and Excellence (aka UCARE) in Hong Kong and completed the traditional Chinese UCT. The internal consistency, test-retest reliability, construct validity, convergent validity, known-group validity, and sensitivity to change of the traditional Chinese UCT were evaluated.
    UNASSIGNED: We recruited 162 CU patients (80.9% female; age 50 ± 14 years) with a mean (median) ± standard deviation baseline UCT score of 8.8 (8) ± 4.7. Overall, Chinese UCT showed excellent internal consistency (Cronbach α and McDonald ω = 0.948), as well as test-retest reliability (intraclass correlation coefficient = 0.916 [95% confidence interval = 0.866-0.953]). Exploratory factor analysis revealed a unidimensional structure and confirmed its construct validity. Strong correlation between UCT and the 7-day urticaria activity score (UAS7) attested to its convergent validity (ρ = -0.699, P < .001). Its known-group validity was supported by significantly different UCT scores among patient subgroups with different disease activity. The Chinese UCT also demonstrated good sensitivity to change, as reflected by the significant correlation between changes in UCT and UAS7 scores (ρ = 0.491, P < .001).
    UNASSIGNED: The traditional Chinese UCT is a valid, reliable, and sensitive-to-change instrument among Hong Kong Chinese with CU.
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    洪水综合征是指慢性腹水合并肝硬化患者的脐疝破裂。这些破裂可能会将感染引入腹部,因此需要紧急手术。然而,由于凝血病,这些患者在这些手术中处于高风险,低血压和电解质失衡。在我们的系列中,我们描述了6例患者,这些患者的严重程度不同,并接受了标准的主要解剖修复和引流治疗方案.此外,我们评估了这些患者的Child-Turcotte-Pugh(CTP)和终末期肝病模型(MELD)评分,并将其与术后结局相关联.这种手术技术在CTP和MELD评分预测术后安全期的患者中具有良好的效果。
    Flood syndrome refers to ruptured umbilical hernias in patients with chronic ascites with underlying liver cirrhosis. These ruptures may introduce infection into the abdomen and hence require emergency surgery. However, these patients are at high risk during these procedures owing to coagulopathy, hypotension and electrolyte imbalances. In our series, we describe six patients who presented with varying degrees of severity and were treated with a standardised protocol of primary anatomic repair and drain placement. Furthermore, we assessed the Child-Turcotte-Pugh (CTP) and Model for End-Stage Liver Disease (MELD) scores in these patients and correlated them to postoperative outcomes. This surgical technique has a good outcome in patients whose CTP and MELD scores predict a safe postoperative period.
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  • 文章类型: Journal Article
    本手稿的目的是开发基于证据的临床算法,用于评估和管理自发性,简单的分娩和阴道分娩。人口是处于任何分娩阶段的孕妇,单身人士,在低收入和中等收入国家的医疗机构中,足月妊娠的并发症风险较低。我们搜索了相关的已发布算法,指导方针,对Cochrane图书馆的系统评价和初步研究,PubMed®和Google,使用与自发相关的术语,截至2023年6月1日,简单的分娩和分娩。开发了三种病例方案来涵盖自发的评估和管理,首先不复杂,第二和第三阶段的劳动。算法提供了定义途径,评估,诊断和链接到其他算法在这个系列的并发症的管理。我们已经开发了三种临床算法来支持自发的循证决策,简单的分娩和阴道分娩。这些算法可能有助于指导医护人员建立尊重的护理,在需要的地方采取适当的干预措施,并有可能减少分娩和分娩期间不必要的干预措施。
    The aim of this manuscript is to develop evidence-based clinical algorithms for the assessment and management of spontaneous, uncomplicated labour and vaginal birth. The population is pregnant women at any stage of labour, with singleton, term pregnancies considered to be at low risk of developing complications in health facilities in low and middle income countries. We searched for relevant published algorithms, guidelines, systematic reviews and primary research studies on Cochrane Library, PubMed® and Google, using terms related to spontaneous, uncomplicated labour and childbirth up to 1 June 2023. Three case scenarios were developed to cover the assessment and management of spontaneous, uncomplicated first, second and third stages of labour. The algorithms provide pathways for definition, assessments, diagnosis and links to other algorithms in this series for the management of complications. We have developed three clinical algorithms to support evidence-based decision-making during spontaneous, uncomplicated labour and vaginal birth. These algorithms may help to guide healthcare staff to institute respectful care, with appropriate interventions where needed, and potentially will reduce the unnecessary use of interventions during labour and childbirth.
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  • 文章类型: Case Reports
    自发性脊髓硬膜外血肿(SSEH)很少发生。如果没有早期诊断,SSEH可导致神经功能缺损的急性发作。我们报告了一例65岁的男性糖尿病患者,他因左肩胛骨和胸骨后剧烈剧烈疼痛而被急诊收治。他被误诊为心血管疾病,直到进行性双侧截瘫和下肢麻木发作。磁共振成像显示胸腹侧SSEH。手术切除硬膜外血肿及椎板切除术减压。除了尿潴留,术后双侧下肢截瘫和麻木缓解。由于在没有治疗或延迟干预的情况下神经系统预后不良的风险很高,建议及时手术清除血肿和止血,以确保良好的神经系统预后。
    Spontaneous spinal epidural hematoma (SSEH) rarely occurs. Without early diagnosis, SSEH can lead to the acute onset of neurologic deficits. We report the case of a 65-year-old male with diabetes mellitus who was admitted to our emergency department with a chief complaint of sharp and severe pain in the left scapula and behind the sternum. He was misdiagnosed with cardiovascular disease until the onset of progressive bilateral paraplegia and lower limb numbness. Magnetic resonance imaging revealed a ventral thoracic SSEH. Surgical treatment to remove epidural hematoma and laminectomy for decompression were performed. Except for urine retention, bilateral lower limb paraplegia and numbness were alleviated postoperatively. Due to the high risk of poor neurological outcomes without treatment or with delayed intervention, timely surgical evacuation of the hematoma and hemostasis are recommended to ensure favorable neurological outcomes.
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  • 文章类型: Case Reports
    孤立的自发性肠系膜上动脉(SMA)夹层相对罕见。经常在横断面成像上偶然发现,经常非手术管理。我们介绍了一名出现胸痛并被发现患有SMA夹层的患者。
    Isolated spontaneous superior mesenteric artery (SMA) dissection is relatively rare. Often found incidentally on cross-sectional imaging, often managed non-operatively. We present a patient who presented with chest pain and was found to have a SMA dissection.
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  • 文章类型: Journal Article
    术语“荨麻疹”最早由威廉·库伦在18世纪提出。荨麻疹是一种常见的肥大细胞介导的皮肤疾病,表现为瘙痒性风团,血管性水肿,或者两者兼而有之。分为急性(≤6周)或慢性(>6周),分为自发性(无明确触发)或诱导性(明确和亚型特异性触发)。关于荨麻疹定义的国际指南,分类,诊断,荨麻疹的管理每4年修订一次。全球荨麻疹参考和卓越中心网络,最大和最活跃的荨麻疹专家联盟,为医生和患者提供了几项研究,教育,和数字护理计划。
    The term \"urticaria\" was first introduced by William Cullen in the eighteenth century. Urticaria is a common mast cell-mediated cutaneous disease presenting with pruritic wheals, angioedema, or both. It is classified as acute (≤6 weeks) or chronic (>6 weeks) and as spontaneous (no definite triggers) or inducible (definite and subtype-specific triggers). The international urticaria guideline on the definition, classification, diagnosis, and management of urticaria is revised every 4 years. The global network of Urticaria Centers of Reference and Excellence, the biggest and most active consortium of urticaria specialists, offers physicians and patients several research, educational, and digital care initiatives.
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