■不受控制的慢性荨麻疹(CU)会严重影响身体和社会心理健康以及生活质量。患者报告的结果指标对于衡量疾病控制至关重要。指南建议使用荨麻疹控制测试(UCT)来监测CU并指导临床管理。然而,UCT的繁体中文版本尚未得到验证。
■我们试图在香港的中国CU患者中验证传统的中国UCT。
■CU患者在香港荨麻疹参考和卓越中心(又名UCARE)注册,并完成了传统的中国UCT。内部一致性,测试-重测可靠性,构造效度,收敛有效性,已知组有效性,并评估了对传统中国UCT变化的敏感性。
■我们招募了162名CU患者(80.9%为女性;年龄50±14岁),平均(中位数)±标准偏差基线UCT评分为8.8(8)±4.7。总的来说,中国UCT表现出优异的内部一致性(Cronbachα和McDonaldω=0.948),以及重测信度(组内相关系数=0.916[95%置信区间=0.866-0.953])。探索性因子分析揭示了一维结构,并证实了其结构有效性。UCT与7天荨麻疹活动评分(UAS7)之间的强相关性证明了其收敛有效性(ρ=-0.699,P<.001)。其已知的组有效性得到了具有不同疾病活动的患者亚组之间明显不同的UCT评分的支持。中国UCT也表现出良好的变化敏感性,如UCT和UAS7评分变化之间的显著相关性所反映的(ρ=0.491,P<.001)。
■繁体中文UCT是有效的,可靠,以及香港华人与CU的敏感易变乐器。
UNASSIGNED: Uncontrolled chronic urticaria (CU) can severely affect physical and psychosocial health as well as quality of life. Patient-reported outcome measures are crucial for measuring disease control. The Urticaria Control Test (UCT) is recommended by guidelines to monitor CU and guide clinical management. However, the traditional Chinese version of the UCT has not yet been validated.
UNASSIGNED: We sought to validate the traditional Chinese UCT among Chinese CU patients in Hong Kong.
UNASSIGNED: Patients with CU were enrolled at a Urticaria Centre of Reference and Excellence (aka UCARE) in Hong Kong and completed the traditional Chinese UCT. The internal consistency, test-retest reliability, construct validity, convergent validity, known-group validity, and sensitivity to change of the traditional Chinese UCT were evaluated.
UNASSIGNED: We recruited 162 CU patients (80.9% female; age 50 ± 14 years) with a mean (median) ± standard deviation baseline UCT score of 8.8 (8) ± 4.7. Overall, Chinese UCT showed excellent internal consistency (Cronbach α and McDonald ω = 0.948), as well as test-retest reliability (intraclass correlation coefficient = 0.916 [95% confidence interval = 0.866-0.953]). Exploratory factor analysis revealed a unidimensional structure and confirmed its construct validity. Strong correlation between UCT and the 7-day urticaria activity score (UAS7) attested to its convergent validity (ρ = -0.699, P < .001). Its known-group validity was supported by significantly different UCT scores among patient subgroups with different disease activity. The Chinese UCT also demonstrated good sensitivity to change, as reflected by the significant correlation between changes in UCT and UAS7 scores (ρ = 0.491, P < .001).
UNASSIGNED: The traditional Chinese UCT is a valid, reliable, and sensitive-to-change instrument among Hong Kong Chinese with CU.