{Reference Type}: Journal Article {Title}: The Definition, Classification, and History of Urticaria. {Author}: Maurer M;Pereira MP;Kolkhir P; {Journal}: Immunol Allergy Clin North Am {Volume}: 44 {Issue}: 3 {Year}: 2024 Aug {Factor}: 3.152 {DOI}: 10.1016/j.iac.2024.03.001 {Abstract}: The term "urticaria" was first introduced by William Cullen in the eighteenth century. Urticaria is a common mast cell-mediated cutaneous disease presenting with pruritic wheals, angioedema, or both. It is classified as acute (≤6 weeks) or chronic (>6 weeks) and as spontaneous (no definite triggers) or inducible (definite and subtype-specific triggers). The international urticaria guideline on the definition, classification, diagnosis, and management of urticaria is revised every 4 years. The global network of Urticaria Centers of Reference and Excellence, the biggest and most active consortium of urticaria specialists, offers physicians and patients several research, educational, and digital care initiatives.