%0 Journal Article
%T The Definition, Classification, and History of Urticaria.
%A Maurer M
%A Pereira MP
%A Kolkhir P
%J Immunol Allergy Clin North Am
%V 44
%N 3
%D 2024 Aug
%M 38937006
%F 3.152
%R 10.1016/j.iac.2024.03.001
%X The term "urticaria" was first introduced by William Cullen in the eighteenth century. Urticaria is a common mast cell-mediated cutaneous disease presenting with pruritic wheals, angioedema, or both. It is classified as acute (≤6 weeks) or chronic (>6 weeks) and as spontaneous (no definite triggers) or inducible (definite and subtype-specific triggers). The international urticaria guideline on the definition, classification, diagnosis, and management of urticaria is revised every 4 years. The global network of Urticaria Centers of Reference and Excellence, the biggest and most active consortium of urticaria specialists, offers physicians and patients several research, educational, and digital care initiatives.