■为了描述内部的方差,中间,和视网膜外层厚度(IRT,捷运,和ORT)在不同年龄段正常眼睛的儿童和青少年的黄斑区。
■这项横断面研究招募了5-18岁正常眼睛的受试者。通过光学相干断层扫描(6mm×6mmAngioScan-Optovue)扫描黄斑。定义了四个年龄组(≤7、7-10、11-14和≥14岁)。分析年龄和性别的影响因素。
■登记了69名受试者的一百三十九只眼睛,平均年龄为10.92±3.51岁。男性平均黄斑厚度(MT)为297.32±11.05,女性为303.197±13.32(P=0.01,t检验)。各老化组MT分别为301.47±2.5、295.53±1.71、300.81±2.12和298.6±1.87(P=0.17,方差分析)。在中央凹区域和主要在IRT中发现了性别之间的显着差异。没有注意到眼睛之间的相关性。我们观察到RT在生长过程中波动,性别对RT的进化有一定影响。所有黄斑区的IRT和MRT都发生了相互变化,而ORT在所有年龄段的儿童和青少年中扩展。
■在这项研究中,在儿科组中没有观察到眼睛之间的亚段视网膜厚度差异,而性别对中央凹IRT有一定影响。尽管这项研究不是纵向研究,我们可以深入了解儿童和青少年视网膜厚度的发育变化及其临床应用。
UNASSIGNED: To describe the variance of inner, middle, and outer retinal layer thicknesses (IRT, MRT, and ORT) at the macular area in children and adolescents with normal eyes in different age groups.
UNASSIGNED: This cross-sectional study enrolled subjects aged 5-18 years with normal eyes. The macula was scanned by optical coherence tomography (6 mm × 6 mm AngioScan-Optovue). Four age groups were defined (≤7, 7-10, 11-14, and ≥14 years). The influences of age and gender were analyzed.
UNASSIGNED: One hundred and thirty-nine eyes of 69 subjects with a mean age of 10.92 ± 3.51 years were registered. The mean whole macular thickness (MT) was 297.32 ± 11.05 in males and 303.197 ± 13.32 in females (P = 0.01, t-test). The MT in each aging group was 301.47 ± 2.5, 295.53 ± 1.71, 300.81 ± 2.12, and 298.6 ± 1.87, subsequently (P = 0.17, analysis of variance test). Significant differences were found between the sexes at the perifoveal area and mainly in IRT. No correlation between eyes was noted. We observed that the RT fluctuates during growth and that gender has some influence on the evolution of RT. IRT and MRT changed reciprocally in all macular areas, whereas ORT expanded in all age groups of children and adolescents.
UNASSIGNED: No subsegmental retinal thickness difference between eyes was observed in pediatric groups in this study, while gender had some influence on perifoveal IRT. Despite the fact that this study is not a longitudinal study, we can get some insight into the developmental changes in retinal thickness and its clinical applications in children and adolescents.