PDF(Pubmed)
Abstract：
UNASSIGNED: To report the prevalence, clinical characteristics and risk factors for paracentral acute middle maculopathy (PAMM) following acute primary angle closure (APAC) and acute primary angle closure glaucoma (APACG).
UNASSIGNED: This retrospective study consecutively recruited patients diagnosed with APAC or APACG. Based on the spectral domain optical coherence tomography characteristics, PAMM eyes were divided into three stages. Characteristics of different stages such as the time from symptoms to treatment (TST), retinal thickness and BCVA improvement were analyzed. The risk factors of PAMM were evaluated by binary logistic regression models.
UNASSIGNED: A total of 781 eyes of 781 APAC or APACG patients were included, and PAMM was found in 22 (2.9%) of them. Stage III eyes had a significantly longer TST than stage I eyes (P = 0.008) while exhibiting significantly thinner retinal thicknesses (P < 0.0001). The BCVA improvement was significantly worse in the eyes treated in stage III than in those treated in stage I (P = 0.008). Older age, longer axial length and without type 2 diabetes were associated with a lower risk of incident PAMM (OR = 0.95, P = 0.028; OR = 0.52, P = 0.019; OR = 3.92, P = 0.022).
UNASSIGNED: PAMM can be secondary to APAC or APACG at a rate of 2.9%. Different visual outcomes were observed in patients who received the intervention at different stages of PAMM. Younger patients with a shorter axial length and type 2 diabetes were found to be more susceptible to PAMM.
UNASSIGNED: This retrospective study consecutively recruited patients diagnosed with APAC or APACG. Based on the spectral domain optical coherence tomography characteristics, PAMM eyes were divided into three stages. Characteristics of different stages such as the time from symptoms to treatment (TST), retinal thickness and BCVA improvement were analyzed. The risk factors of PAMM were evaluated by binary logistic regression models.
UNASSIGNED: A total of 781 eyes of 781 APAC or APACG patients were included, and PAMM was found in 22 (2.9%) of them. Stage III eyes had a significantly longer TST than stage I eyes (P = 0.008) while exhibiting significantly thinner retinal thicknesses (P < 0.0001). The BCVA improvement was significantly worse in the eyes treated in stage III than in those treated in stage I (P = 0.008). Older age, longer axial length and without type 2 diabetes were associated with a lower risk of incident PAMM (OR = 0.95, P = 0.028; OR = 0.52, P = 0.019; OR = 3.92, P = 0.022).
UNASSIGNED: PAMM can be secondary to APAC or APACG at a rate of 2.9%. Different visual outcomes were observed in patients who received the intervention at different stages of PAMM. Younger patients with a shorter axial length and type 2 diabetes were found to be more susceptible to PAMM.
摘要：
■要报告患病率，急性原发性闭角型青光眼（APAC）和急性原发性闭角型青光眼（APACG）后中央旁急性中间型黄斑病变（PAMM）的临床特征和危险因素。
■这项回顾性研究连续招募了诊断为APAC或APACG的患者。基于谱域光学相干层析成像的特点,PAMM眼睛分为三个阶段。不同阶段的特征，如从症状到治疗的时间（TST），分析视网膜厚度和BCVA改善情况。采用二元Logistic回归模型评价PAMM的危险因素。
■共包括781只APAC或APACG患者的781只眼，其中22人(2.9%)发现PAMM。III期眼睛的TST明显长于I期眼睛（P=0.008），同时表现出明显较薄的视网膜厚度（P<0.0001）。III期治疗的眼睛的BCVA改善明显比I期治疗的眼睛差（P=0.008）。年纪大了,较长轴长和无2型糖尿病与PAMM的发生率较低相关(OR=0.95,P=0.028;OR=0.52,P=0.019;OR=3.92,P=0.022).
■PAMM可以以2.9％的比率仅次于APAC或APACG。在PAMM的不同阶段接受干预的患者观察到不同的视觉结果。发现轴向长度较短和2型糖尿病的年轻患者更容易患PAMM。
■这项回顾性研究连续招募了诊断为APAC或APACG的患者。基于谱域光学相干层析成像的特点,PAMM眼睛分为三个阶段。不同阶段的特征，如从症状到治疗的时间（TST），分析视网膜厚度和BCVA改善情况。采用二元Logistic回归模型评价PAMM的危险因素。
■共包括781只APAC或APACG患者的781只眼，其中22人(2.9%)发现PAMM。III期眼睛的TST明显长于I期眼睛（P=0.008），同时表现出明显较薄的视网膜厚度（P<0.0001）。III期治疗的眼睛的BCVA改善明显比I期治疗的眼睛差（P=0.008）。年纪大了,较长轴长和无2型糖尿病与PAMM的发生率较低相关(OR=0.95,P=0.028;OR=0.52,P=0.019;OR=3.92,P=0.022).
■PAMM可以以2.9％的比率仅次于APAC或APACG。在PAMM的不同阶段接受干预的患者观察到不同的视觉结果。发现轴向长度较短和2型糖尿病的年轻患者更容易患PAMM。
